Reaction time is the time delay between the sensory stimulus and initiation of a motor response to a stimulus. Reaction time provides the information about the cognitive performance under certain conditions .In this paper energy drink and nicotine effects on the reaction time are investigated. This study is designed to acquire reaction/ response time from young adults whom consumes energy drinks and smokes frequently. Chemicals like nicotine, caffeine, taurine and glucose affects our brain in the way that these chemicals act to decrease the reaction time and improve cognitive performance and motor response. Using means of Delta Time as features and through statistical analysis it is concluded that there is difference in response time but not significant enough (p > 0.05). After consumption the reaction time decreases slightly which cannot be considered significant to influence brain activity.