Physiologische Bedeutung des Ammoniaks im Organismus der Wirbeltiere

H, Schneller

doi:10.1007/bf02320724

Cited by 5 publications

(1 citation statement)

References 134 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Since the fall in urea was, in these experiments, accompanied by an increase in ammonia (it should be noted that the fall in urea N was not compensated by the fall in dietary N intake + the increase in ammonia N) acidosis may be considered to have been the casual factor. However, Schneller (1935) and Krebs (1936) deny that urea is the precursor of urinary ammonia and furthermore the ammonia curves obtained (see Graphs 11,12,15 and 1G) were not similar to those normally found in acidosis.…”

Section: Metabolism Of Trichinosed Rats (10)mentioning

confidence: 83%

The Metabolism of Trichinosed Rats During the Early Phase of the Disease

Rogers

1941

J. Helminthol.

View full text Add to dashboard Cite

The changes in protein digestion, crude fibre digestion and the chief urinary constituents found in four rats after experimental infection with Trichinella spiralis are detailed.Diarrhoea and anorexia occurred during the period 8 to 12 days after infection when protein digestion fell to its lowest point. It is suggested that this was due to antiproteases secreted by the adult parasites and to mechanical damage in the intestinal mucosa caused by their movements.Urinary N rose immediately after infection in “non-resistant” rats. This was followed by a period of decreased N output after which the excretion rate rose steeply.The urea output also rose immediately after infection in “non-resistant” rats. During the period 4 to 12 days from the time of infection urea excretion fell. Thereafter there was a great increase in its rate of output. Most of these changes have been attributed to toxins elaborated by the adult parasites for massive larval invasion of the tissues probably did not occur till after the experiments were terminated.Ammonia excretion rose as urinary urea decreased. The fall in urea N was not compensated by the rise in ammonia N + the fall in dietary N intake. The ammonia output returned rapidly to normal suggesting that the excess ammonia was not produced in response to acidosis when the urea excretion rate rose.Creatine excretion showed a marked fall during the period 4 to 12 days after infection. Urinary creatine and creatinine rose steeply following this period. Possible reasons for these variations are discussed.

show abstract

Section: Metabolism Of Trichinosed Rats (10)mentioning

confidence: 83%