2024
DOI: 10.1093/bbb/zbae169
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Physiology of vitamin B12: a study on its molecular mechanisms using a Caenorhabditis elegans model

Tomohiro Bito

Abstract: Vitamin B12 (B12) is a water-soluble substance that is a member of the B-vitamin family. Its recommended daily dose in adult men and women is 2.4 µg, which is the lowest among the 13 vitamins. B12 deficiency causes megaloblastic anemia and neurological disorders. It is also associated with cognitive decline, growth retardation, infertility, and other symptoms. Nevertheless, the detailed mechanisms of which remain unclear. Caenorhabditis elegans is a small organism, with a length of approximately… Show more

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