Physiopathological inference by computer

A statistical approach to logical inference in endocrine physiopathology

“…Solving these equations gives the expected TRH level and hence provides estimations of the prior distributions p(TRH level I Hi). These distributions are given in Table IV. A difficulty arises for the observations belonging to the normal state group: a normal TRH level is expected under each hypothesis (Table IV) and among 30 subjects, 8 have a decreased TRH level (Table 111). This contradiction between the model and the observed data can be explained by discretization errors.…”

“…The logical function f D formalizing these facts is defined by Their respective meanings are Equation (7): if S;-hypersecretion inducing events occur without simultaneous hyposecretion inducing events, then Si is increased. Equation (8): i f Si-hyposecretion inducing events occur without simultaneous hypersecretion inducing events, then Si is decreased. Equation (9): if no event that would induce hypersecretion or hyposecretion of Si is present, then Si is neither increased nor decreased, i.e.…”