“…Most of the studies [ 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 ] targeted active TrPs (i.e., those in which referred pain reproduced the patient’s knee symptoms) with the needle, whereas one trial [ 40 ] targeted specific points chosen based on the most common places of TrPs at the quadriceps muscle, as originally described by Simons et al [ 12 ] The needling technique was homogenous; eight trials [ 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 ] used reported the presence of local twitch responses during the intervention, one [ 49 ] did not report it and the last one used superficial, not deep, dry needling [ 40 ]. However, there was heterogenicity in the number and frequency of sessions and the type of sham or comparator.…”