Phytic acid-zinc ion interactions: a calorimetric and titrimetric study

Martin, C. Dianne; Evans, William J.

doi:10.1016/0162-0134(86)80039-3

Cited by 38 publications

(4 citation statements)

References 26 publications

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“…On the other hand, Vasca et al obtained the CuH 5 Phy 5− and Cu 2 H 3 Phy 5− species with log K 15 = 2.63 and log K 23 = 8.97, respectively. Martin and Evans carried out a calorimetric and titration study on the interaction of phytate with Zn 2+ in the range 2.5 ≤ pH ≤ 11.0, in KCl at I = 0.2 mol·L −1 and T = 298.15 K. The phytate complex formation was obtained at pH < 6, with ∼3.5 mol of Zn 2+ bound per mol of phytate. By means of potentiometric titrations, they also determined the formation constants per phosphate group bound by Zn 2+ at different metal-to-ligand ratios, while the apparent binding heats at four molar ratios were determined from calorimetric titrations carried out in the range 2.6 ≤ pH ≤ 6.1.…”

Section: Resultsmentioning

confidence: 99%

Electrochemical Study on the Stability of Phytate Complexes with Cu²⁺, Pb²⁺, Zn²⁺, and Ni²⁺: A Comparison of Different Techniques

et al. 2010

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The formation constants of various M/Phy systems (M = Cu2+, Zn2+, Pb2+, Ni2+; Phy = Phytate) were determined in NaNO3 solutions at 0.1 ≤ I/mol·L−1 ≤ 1.0 and T = 298.15 K, by potentiometry and voltammetry. The formation constants of the Cu/Phy and Zn/Phy species, already determined, were reanalyzed together with new voltammetric and potentiometric experiments at low concentrations. A new potentiometric and voltammetric study was carried out on the Ni/Phy and Pb/Phy systems. For all of the investigated systems, the dependence on ionic strength was modeled by the Debye−Hückel and the specific interaction theory (SIT) approaches. The sequestering ability of phytate was evaluated toward the considered cations by calculating the pL50 values (i.e., the total ligand concentration necessary to bind 50 % of the cation present in trace) at different ionic strengths and pH. A complete set of “suggested” formation constants was provided. A comparison between the formation constants obtained for the Zn/Phy, Cu/Phy, and Pb/Phy systems reveals that the interactions of phytate with Zn2+, Cu2+, and Pb2+ are quite similar, while the Ni/Phy species showed a weaker complexation. For example, for the MH3Phy species, log K 3 = 7.81, 7.51, 7.10, and 5.97 for Zn2+, Cu2+, Pb2+, and Ni2+, respectively. The same trend is observed concerning the pL50. Their dependence on pH and ionic strength was modeled by two empirical equations.

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Section: Resultsmentioning

confidence: 99%

Electrochemical Study on the Stability of Phytate Complexes with Cu²⁺, Pb²⁺, Zn²⁺, and Ni²⁺: A Comparison of Different Techniques

et al. 2010

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“…The above discussions indicate that there is no consensus on the degree to which phytate impacts the physiological accessibility of metal cations (Martin and Evans, 1986). Although the phytic acid contents of cereal grains have been shown to affect adversely the intestinal absorption of ions like zinc and iron (Oberleas, 1973; Ellis and Morris, 1986), others report that phytic acid poses no hindrance to iron uptake and increases Cu uptake (Lee et al, 1988).…”

Section: Resultsmentioning

confidence: 99%

Phytate content of Taiwanese diet determined by phosphorus-31 Fourier transform nuclear magnetic resonance spectroscopy

Wang¹,

Tsay²,

Lee³

et al. 1992

J. Agric. Food Chem.

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“…However, it requires human trials and prior approval by several health organizations for commercial use. Hypothetically, the selective binding of phytic acid with organic additives can also be achieved by altering the processing conditions (Martin & Evans, 1986b). Thus, selecting a specific additive would result in quick and selective interaction with phytic acid and form complexes with phytate.…”

Section: Economic Aspects and Future Directionsmentioning

confidence: 99%

Phytic acid and its reduction in pulse matrix: Structure–function relationship owing to bioavailability enhancement of micronutrients

Sarkhel

Roy

2022

J Food Process Engineering

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The bioavailability of minerals and proteins in the pulse is endured due to the presence of antinutrient phytic acid. Phytic acid is a proton donor that produces hydrogen ions (H + ) and "phytate" anion, which readily forms salts with available minerals and protein. These phytate complexes are not bioavailable to humans and led to several public health problems like anemia, skeletal abnormalities, osteoporosis, malabsorption, and kwashiorkor syndrome due to Fe, Mn, Ca, Zn, and protein deficiency. Thus, it is a severe concern to the vegetarian population who strongly rely upon pulses to fulfill their daily nutrition requirements. Improving the bioavailability of micronutrients in the pulse matrix requires reduction of phytic acid. A phytic acid reduction strategy should ensure its efficient reduction leading to enhanced micronutrient bioavailability. This article provides a throughout view of the available phytic acid reduction technologies conducted at the postharvest stages of pulse processing.The mechanism of phytic acid reduction during conventional (soaking, cooking, and germination) and novel processing (irradiation, ultrasound, and high pressure) regarding its degradation and interaction with other components has been explored here, providing insight into structure-function relationships. Further, an in-depth analysis of the combined treatments offering better phytic acid reductions has been explained in the light of structural alteration of phytic acid to its lower inositol phosphates. The summarized data on prospects and drawbacks of different phytic acid reduction strategies would provide background information to explore the futuristic possibilities for efficient phytic acid reduction and micronutrient fortification. Practical ApplicationsThe presence of phytic acid in the pulse matrix restricts the micronutrient absorption by complexing with micronutrients leading to their ineffectiveness. The bottom-line population of the income pyramid, who are unable to intake micronutrients from other sources, suffers from several public health problems related to nutrient or combined nutrient deficiencies. Therefore, the degradation of phytic acid in pulses is necessary. This article aims to provide a comprehensive overview and explanation of phytic acid degradation during various postharvest pulses processing. The chelation

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Phytic acid-zinc ion interactions: a calorimetric and titrimetric study

Cited by 38 publications

References 26 publications

Electrochemical Study on the Stability of Phytate Complexes with Cu²⁺, Pb²⁺, Zn²⁺, and Ni²⁺: A Comparison of Different Techniques

Electrochemical Study on the Stability of Phytate Complexes with Cu²⁺, Pb²⁺, Zn²⁺, and Ni²⁺: A Comparison of Different Techniques

Phytate content of Taiwanese diet determined by phosphorus-31 Fourier transform nuclear magnetic resonance spectroscopy

Phytic acid and its reduction in pulse matrix: Structure–function relationship owing to bioavailability enhancement of micronutrients

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Phytic acid-zinc ion interactions: a calorimetric and titrimetric study

Cited by 38 publications

References 26 publications

Electrochemical Study on the Stability of Phytate Complexes with Cu2+, Pb2+, Zn2+, and Ni2+: A Comparison of Different Techniques

Electrochemical Study on the Stability of Phytate Complexes with Cu2+, Pb2+, Zn2+, and Ni2+: A Comparison of Different Techniques

Phytate content of Taiwanese diet determined by phosphorus-31 Fourier transform nuclear magnetic resonance spectroscopy

Phytic acid and its reduction in pulse matrix: Structure–function relationship owing to bioavailability enhancement of micronutrients

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Electrochemical Study on the Stability of Phytate Complexes with Cu²⁺, Pb²⁺, Zn²⁺, and Ni²⁺: A Comparison of Different Techniques

Electrochemical Study on the Stability of Phytate Complexes with Cu²⁺, Pb²⁺, Zn²⁺, and Ni²⁺: A Comparison of Different Techniques