Phyto-Pharmacological Investigation of Marine Red Algae Kappaphycus alvarezii (Doty) Doty ex Silva for Oral Diseases

Sharan, Leena; Vennila, J. Jannet

doi:10.1615/interjalgae.v23.i2.40

Cited by 5 publications

(2 citation statements)

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“…Rhodophyta is a groups of seaweeds with pharmacological properties and contains numerous natural compounds (Cotas et al, 2020). Therefore, two studies have investigated that extract and/or compounds from Rhodophyta have therapeutic potential for periodontitis (Cherian et al, 2019;Sharan & Vennila, 2021). A study obtained Kappaphycus alvarezii MeOH extract (KAM) and isolated marine bromophenol from KAM (KAB) (Cherian et al, 2019).…”

Section: Fisheries and Aquatic Sciencesmentioning

confidence: 99%

“…Additionally, KAB and KAM suppressed the mRNA expression of peptidyl arginine deiminase (PPAD), Rgp, and hemagglutinin A (HgA). The other study obtained K. alvarezii extracts using different polarity solvents, including EtOH (KAE), ethyl acetate (KAEA), and chloroform (KAC) (Sharan & Vennila, 2021). After that, the authors evaluated the pharmacological effect of K. alvarezii extracts.…”

Section: Fisheries and Aquatic Sciencesmentioning

confidence: 99%

See 1 more Smart Citation

Therapeutic effect of marine bioactive substances against periodontitis based on in vitro, in vivo, and clinical studies

Lee¹,

Kwon²,

Jung³

2023

Fish Aquat Sci

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Marine bioactive substances (MBS), such as phlorotannins, collagens, peptides, sterols, and polysaccharides, are increasing attention as therapeutic agents for several diseases due to their pharmacological effects. Previous studies have demonstrated the biological activities of MBS including antibacterial, anticoagulant, antidiabetic, antimicrobial, anti-inflammatory activities. Among numerous human diseases, periodontitis is one of the high-prevalence inflammatory diseases in the world. To treat periodontitis, several surgeries (bone grafting, flap surgery, and soft tissue graft) are usually used. However, the surgery for patients with chronic periodontitis induces several side effects, including additional inflammatory responses at the operated site, chronic wound healing, and secondary surgery. Therefore, this review assessed the most recent trends in MBS using Google Scholar, PubMed, and Web of Science search engines to develop marine-derived therapeutic agents for periodontitis. Further, we summarized the current applications and therapeutic potential of MBS to serve as a reference for developing novel technologies applied to MBS against periodontitis treatment.

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