Phytoalexins: Current and possible future applications in human health and diseases control

Egbuonu, Anthony Cemaluk C.; Eneogwe, Juliet C

doi:10.15406/ijmboa.2018.03.00061

Cited by 3 publications

(2 citation statements)

References 70 publications

(70 reference statements)

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“…There are studies on the antifungal effects of such compounds in plants. Aucuparin and noraucuparin isolated from “Florina” apple plantations showed a significant inhibitory effect on the germination of the fungus Venturia inaequalis [ 93 ]. Of several biphenyls and dibenzofurans tested for their antibacterial activity against some strains of Erwinia amylovora , 3,5-dihydroxybiphenyl was the most effective [ 94 ].…”

Section: Biopharmaceutical Properties Of Rowanberriesmentioning

confidence: 99%

Rowanberry—A Source of Bioactive Compounds and Their Biopharmaceutical Properties

Arvinte,

Senila,

Becze

et al. 2023

Plants

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After a period of intense development in the synthesis pharmaceutical industry, plants are making a comeback in the public focus as remedies or therapeutic adjuvants and in disease prevention and ensuring the wellbeing and equilibrium of the human body. Plants are being recommended more and more in alimentation, in their natural form, or as extracts, supplements or functional aliments. People, in general, are in search of new sources of nutrients and phytochemicals. As a result, scientific research turns to lesser known and used plants, among them being rowanberries, a species of fruit very rich in nutrients and underused due to their bitter astringent taste and a lack of knowledge regarding the beneficial effects of these fruit. Rowan fruits (rowanberries) are a rich source of vitamins, polysaccharides, organic acids and minerals. They are also a source of natural polyphenols, which are often correlated with the prevention and treatment of modern world diseases. This article presents the existing data regarding the chemical composition, active principles and biopharmaceutical properties of rowan fruits and the different opportunities for their usage.

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Section: Biopharmaceutical Properties Of Rowanberriesmentioning

confidence: 99%

Rowanberry—A Source of Bioactive Compounds and Their Biopharmaceutical Properties

Arvinte,

Senila,

Becze

et al. 2023

Plants

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“…Plants utilizes a complex defense mechanism against pest and pathogens, which lead to the production of low molecular weight secondary metabolites. These metabolites have antimicrobial property and are known as Phytoalexins (Egbuonu et al, 2018). Once the microorganism invaded in the plant, the plant in response to the pathogen release the antimicrobial compounds known as phytoalexins in the infected sites.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Potential of Glycyrrhiza Glabra L. Roots: In-Vitro Evidences

Sindhu

Arora

2020

JPTRM

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Background: Plants are easily prone towards microbial infections on exposure to microorganisms and pathogens. In order to defense, plants produce low molecular weight secondary metabolites which were later known as “Phytoalexins”. These molecules have vast therapeutic potential also. Purpose: The purpose of this review is to explore the phytoalexins and their pharmacological effects.Methods: The data included from the articles were published from Web of Science, PubMed, Medline, Scopus, and Embase by using relevant keywords including plants possessing phytoalexins and their specific biological applications.Results: The review insights the potential of phytoalexins in various diseases and to explore have phytoalexins applications in human health and disease control. Conclusions: On the basis of this review we may be conclude that phytoalexins have tremendous potential in the treatment and prevention of various life-threatening diseases like diabetes mellitus, cancer, brain damage, and heart attack.

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Phytochemical Investigation of the Roots of Ipomoea asarifolia and Antiproliferative Activity of the Isolated Compounds against Multiple Myeloma Cells

et al. 2021

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Ipomoea asarifolia is a herbaceous plant belonging to the family Convolvulaceae and is native to tropical regions of Africa, America, and Asia. A dichloromethane root extract showed antiproliferative activity against multiple myeloma cells (RPMI 8226). The phytochemical investigation led to the isolation of 15 compounds. Compounds 1–4, named (4S,8S)-1-(furan-3-yl)-9-hydroxy-4,8-dimethylnonane-1,6-dione, isoferulic acid hexadecyl ester, caffeic acid hexadecyl ester, and asarifolin I, respectively, are described for the first time. The structures of these molecules were established from their NMR, UV, IR spectroscopic, and MS data. 4-Hydroxycinnamic acid hexadecyl ester (5), 4-hydroxycinnamic acid octadecyl ester (6), 4-hydroxycinnamic acid eicosyl ester (7), caffeic acid octadecyl ester (8), pescapreins III, IV, XXI, XXIII, XXV, and XXVI (9–14), and stoloniferin III (15) were also isolated. All compounds were tested against a multiple myeloma cell line (RPMI 8226). When their IC50 value was lower than 10 μM, the compounds were also tested against two other multiple myeloma cell lines, MM.1S and MM.1R. Compound 3 was the most potent, with an IC50 value of 3.0 μM against RPMI 8226 cells.

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Phytoalexins: Current and possible future applications in human health and diseases control

Abstract: In this review, conventional search engines, including Google and relevant search words were used. In particular, current and possible future applications of phytoalexins in human health and diseases control were highlighted.

Cited by 3 publications

References 70 publications

Rowanberry—A Source of Bioactive Compounds and Their Biopharmaceutical Properties

Rowanberry—A Source of Bioactive Compounds and Their Biopharmaceutical Properties

Antioxidant Potential of Glycyrrhiza Glabra L. Roots: In-Vitro Evidences

Phytochemical Investigation of the Roots of Ipomoea asarifolia and Antiproliferative Activity of the Isolated Compounds against Multiple Myeloma Cells

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