Phytochemical and Biopharmaceutical Aspects of Psidium guajava (L.) Essential Oil: A Review

Joseph, Baby; Priya, R

doi:10.3923/rjmp.2011.432.442

Cited by 65 publications

(36 citation statements)

References 26 publications

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“…Thereby, antimicrobial agents attempt to directly reduce the pocket microflora when applied as an adjunct to mechanical debridement. 17 Guava is proven for its antidiarrheal, antimicrobial, 18-22 antiparasitic, 23 antitussive, 24,25 antigenotoxic, antimutagenic, antiallergic, 26,27 anthelmintic, 28 hepatoprotective, and antioxidant properties. 29 It is also reported that it can be beneficial in oral diseases like periodontitis [30][31][32] and gingivitis.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Efficacy of Guava Extract as an Antimicrobial Agent on Periodontal Pathogens

Shetty

Shankarapillai

Vivekanandan

et al. 2018

The Journal of Contemporary Dental Practice

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Section: Discussionmentioning

confidence: 99%

Evaluation of the Efficacy of Guava Extract as an Antimicrobial Agent on Periodontal Pathogens

Shetty

Shankarapillai

Vivekanandan

et al. 2018

The Journal of Contemporary Dental Practice

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“…Although there is two papers about cytotoxic effects of this oil reviewed in [13], no data were available about its toxicity. Here we show the potential antitumor effects of P. guajava EO in an interval of concentration that is in the same range of several cytotoxic drugs already utilized for this type of tumors.…”

Section: Discussionmentioning

confidence: 99%

Antiproliferative activity of Psidium guajava essential oil: a preliminary study

Radice

Chiurato

Guerrini

et al. 2017

Proceedings of MOL2NET 2017, International Conference on Multidisciplinary Sciences, 3rd Edition

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Psidium guajava OE -Antiproliferative activity Abstract.Psidium guajava essential oil (EO) from Ecuador was screened for its antiproliferative activity against three human colon carcinoma cell lines: HCT116 a human colon adenocrcinoma grade II, sensitive to 5-fluorouracil and oxaliplatin; CaCO2, a primary adenocarcinoma grade II; SW620, a highly resistant cell line deriving from a lymph-node mestastasis. Peripheral Blood Mononucleated Cells (PBMC) from a healthy donor buffy coat was utilized as healthy control cells. Cells were treated with increasing concentrations of P. guajava EO (20-800 µg/ml) dissolved in 0.25 DMSO and added to growth medium. 24 or 48 hours after cells were detached with trypsin and number of viable cells was determined by Tripan blue exclusion and/or or calcein-AM method, thus providing percentage of viable cells and rate of proliferation as well. Dose dependent antiproliferative effects were observed, with a percentage of growth inhibition ranging from 40 to 80 % (20-80 µg/ml). 48h treatment did not increased effectiveness of the EO probably because of a short half-life of the oil. Interestingly treating PBMC with 50µg/ml no antiproliferative effects were observed, suggesting that this concentration, corresponding to IC 50 of this OE, did not lead evaluable toxicity to healthy cells such as PBMC. Further studies regarding chemical characterization and combination with commonly utilized anticancer drugs may be done as next step.

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“…The compound cineole which was overexpressed in T1, T2 and T3, as linalool that was overexpressed in T2 possess insecticidal effect [6], while α-terpenil-acetate, with repellent effectiveness [38], was overexpressed in T1, T2 and T3.…”

Section: Resultsmentioning

confidence: 99%

Induction of Defensive Responses in Eucalyptus globulus (Labill) Plants, against Ctenarytaina eucalypti (Maskell) (Hemiptera: Psyllidae)

Troncoso¹,

Becerra²,

Pérez³

et al. 2012

AJPS

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This study evaluated the expression of defense compounds from the secondary metabolism of Eucalyptus globulus plants, subjected to direct and indirect stimuli by the insect Ctenarytaina eucalypti (blue gum Psyllid). Results showed that defense responses were activated in plants in all tested cases. Were detected and identified thirty-two compounds in the leaves of treated plants, of which five compounds differed with the control, and all are part of the chemical defenses from the plants, three of them were oxygenated monoterpenes (borneol, exo-2-hydroxy cineole and thymol), a aromatic carboxylic acid (benzoic acid) and a quinone (6-acethyl-flaviolin). The plants induced by volatile compounds and by indirect entomological manner, showed its capability to synthesize defensive compounds without a wound that promotes these responses. Were also found some constitutive secondary metabolites over expressed in the different inductions compared with the control.

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Phytochemical and Biopharmaceutical Aspects of Psidium guajava (L.) Essential Oil: A Review

Cited by 65 publications

References 26 publications

Evaluation of the Efficacy of Guava Extract as an Antimicrobial Agent on Periodontal Pathogens

Evaluation of the Efficacy of Guava Extract as an Antimicrobial Agent on Periodontal Pathogens

Antiproliferative activity of <em>Psidium guajava</em> essential oil: a preliminary study

Induction of Defensive Responses in <i>Eucalyptus globulus</i> (Labill) Plants, against <i>Ctenarytaina eucalypti</i> (Maskell) (Hemiptera: Psyllidae)

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Phytochemical and Biopharmaceutical Aspects of Psidium guajava (L.) Essential Oil: A Review

Cited by 65 publications

References 26 publications

Evaluation of the Efficacy of Guava Extract as an Antimicrobial Agent on Periodontal Pathogens

Evaluation of the Efficacy of Guava Extract as an Antimicrobial Agent on Periodontal Pathogens

Antiproliferative activity of <em>Psidium guajava</em> essential oil: a preliminary study

Induction of Defensive Responses in &lt;i&gt;Eucalyptus globulus&lt;/i&gt; (Labill) Plants, against &lt;i&gt;Ctenarytaina eucalypti&lt;/i&gt; (Maskell) (Hemiptera: Psyllidae)

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Induction of Defensive Responses in <i>Eucalyptus globulus</i> (Labill) Plants, against <i>Ctenarytaina eucalypti</i> (Maskell) (Hemiptera: Psyllidae)