Phytochemical and Pharmacological Overview of<i>Cistanche</i>Species

Lv, Haining; Zeng, Ke‐Wu; Song, Yuelin; Jiang, Yong; Tu, Pengfei

doi:10.1002/9781118883303.ch14

Cited by 2 publications

(2 citation statements)

References 55 publications

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“…CT tonifies the liver and kidney, nourishes essence and produces blood, moistens the intestines and acts as a laxative, delays senility, and so forth. It has been honored as ‘Ginseng of the desert’ and certified as a medicinal plant by the Chinese Pharmacopoeia due to its remarkable curative effects (Lv et al, 2016; Morikawa et al, 2019; Wang, Zhang, & Xie, 2012). Traditional Chinese medicine (TCM) theory states that rice wine can make kidney‐tonifying drugs more effective.…”

Section: Introductionmentioning

confidence: 99%

Effects of processing on the efficacy and metabolites of Cistanche tubulosa using ultra‐performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry

Xin

et al. 2023

Biomedical Chromatography

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Cistanche tubulosa (CT), a well‐known traditional Chinese medicine, has always been processed with rice wine for the treatment of kidney‐yang deficiency syndrome (KYDS) since time immemorial. To explore the effect of processing on the efficacy and metabolites of CT in vivo, a comprehensive method using ultra‐performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry was established for the analysis of the altered endogenous metabolites in response to the intervention of the raw and processed CT in KYDS model and the metabolites of the absorbed compounds in rats after gastric perfusion. It was shown that CT could improve KYDS, and the effect of the processed product was more significant. A total of 47 differential metabolites were identified in urine. Pathway analysis proved that purine metabolism; alanine, aspartate, and glutamate metabolism; and citrate cycle were the main pathways. Furthermore, 53 prototypes and 48 metabolites have been detected in rats. This was the first systematic research focus on the metabolites of raw and processed CT in vivo, which could provide a scientific basis for explaining the increasing efficiency of the processed CT. Moreover, it provides a valuable strategy for analyzing the chemical components and metabolites of other TCM prescriptions.

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Section: Introductionmentioning

confidence: 99%

Effects of processing on the efficacy and metabolites of Cistanche tubulosa using ultra‐performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry

Xin

et al. 2023

Biomedical Chromatography

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“…12) Chemical research has indicated that phenylethanoid glycosides (PhGs), iridoids, lignans, and polysaccharides are the major constituents of these species, 13,14) and Herba Cistanche extracts have been proved to have a range of pharmacologically active functions that include improving chronic renal disease and constipation in the elderly, increasing learning or memorization abilities, treating Alzheimer's disease (AD), and improving immunity by researchers all over the world. 1,[15][16][17][18] This paper mainly updates the available information about the phytochemical constituents, pharmacological activities and safety of Cistanches Herba to provide useful information for the development of plant-derived drugs and Chinese medicine preparations from this medicinal plant.…”

Section: Introductionmentioning

confidence: 99%

Herba <i>Cistanche</i> (Rou Cong Rong): A Review of Its Phytochemistry and Pharmacology

Wang

Zhang

et al. 2020

Chem. Pharm. Bull.

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Herba Cistanche, known as Rou Cong Rong in Chinese, is a very valuable Chinese herbal medicine that has been recorded in the Chinese Pharmacopoeia. Rou Cong Rong has been extensively used in clinical practice in traditional herbal formulations and has also been widely used as a health food supplement for a long time in Asian countries such as China and Japan. There are many bioactive compounds in Rou Cong Rong, the most important of which are phenylethanoid glycosides. This article summarizes the up-to-date information regarding the phytochemistry, pharmacology, processing, toxicity and safety of Rou Cong Rong to reveal its pharmacodynamic basis and potential therapeutic effects, which could be of great value for its use in future research.

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Phytochemical and Pharmacological Overview ofCistancheSpecies

Cited by 2 publications

References 55 publications

Effects of processing on the efficacy and metabolites of Cistanche tubulosa using ultra‐performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry

Effects of processing on the efficacy and metabolites of Cistanche tubulosa using ultra‐performance liquid chromatography coupled with quadrupole time‐of‐flight mass spectrometry

Herba <i>Cistanche</i> (Rou Cong Rong): A Review of Its Phytochemistry and Pharmacology

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