Phytochemical and pharmacological variability in Golden Thistle functional parts: comparative study of roots, stems, leaves and flowers

Abstract

Scolymus hispanicus or the Golden Thistle, locally known as 'Guernina' or 'Taghediwt', is one of the most appreciated wild vegetables in Morocco. This study aims to characterise the functional chemical and pharmacological variability of Scolymus hispanicus parts (roots, stems, leaves and flowers). The chemical analysis revealed higher content of α-tocopherol in the flowers (2.79 ± 0.07 mg/100 g) and lead to the identification of 3 flavonoids and 13 phenolic acids, with high content of gallic acid in leaves (187.01 ± 10.19 mg/kg); chlorogenic (936.18 ± 92.66 mg/kg) and caffeic (4400.14 ± 191.43 mg/kg) acids in flowers, roots were much more higher in sinapic acid (0.25 ± 0.03 mg/kg) compared to the other parts. Moreover, Scolymus hispanicus ethanolic extracts exhibited interesting antioxidant and antimicrobial properties, promising anti-amylase and anti-glucosidase activities and relevant diuretic effect that confirms its traditional uses.

Evaluation of Antioxidant, Anti‐Inflammatory and Antityrosinase Potential of Extracts from Different Aerial Parts ofRhanterium suaveolensfrom Tunisia

“…In these extracts we have found two subclasses of polyphenols, namely hydroxycinnamic acids (caffeic acid, chlorogenic acid and their derivatives) and glycosides derivated from the two flavonols quercetin and kaempferol ( Table 2). Our results are totally in agreement with the literature, since quercetin and chlorogenic acids were often detected as the main compounds in the aerial parts of plants belonging to the Asteraceae family, such as Anthemis nobilis , [14] Achillea millefolium , [15] Golden thistle , [16] and Rhanteuim suaveolens from Tataouin [9] . Qualitatively, chromatograms coming from the extracts of flowers, leaves and stems of Rs are apparently characterized by similar profiles ( Figure 1), while the total polyphenol abundance order was RSF>RSS>RSL.…”

Screening of the antimicrobial activity of some extracts of edible wild plants in Morocco

“…The extract of this species shows excellent activity against food-borne pathogens E. aeruginosa strains. [4].The antimicrobial properties of this species could be attributed to its chemical composition. Indeed, the different parts of the plant have high levels of α-tocopherol, flavonoids, and phenolic acids that have been associated with the control of foodborne pathogens [4,43].…”

Effect of in vitro gastrointestinal digestion on the total phenolic contents and antioxidant activity of wild Mediterranean edible plant extracts

“…In vitro methods of simulated gastrointestinal digestion have proven to be useful in determining the stability of bioactive compounds under gastrointestinal conditions and the results can be well correlated with those from human studies and animal models [18,19]. The present study focused on four wild edible plants (Beta maritima L., Plantago major L., Oxalis pescaprae L. and Scolymus hispanicus L.) used in Mediterranean diet ( Figure 1 and Table 1) with nutritional and health benefits [8,[20][21][22][23][24][25][26][27]. The aim of the present study was to assess, for the first time, if the total phenolic contents and antioxidant activity of extracts from these species are affected by simulated gastrointestinal digestion.…”