Phytochemical and Toxicological Properties of Sclerotium from the Edible Fungus - Pleurotus tuber-regium

Alaribe, Chinwe S.; Lawal, M.D.; Momoh, Rashidat; Idaholo, Ufoma; Mudabai, Pamela; Adejare, Abdullahi A.

doi:10.26538/tjnpr/v2i5.6

Cited by 3 publications

(2 citation statements)

References 7 publications

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“…Previous studies have demonstrated that organic solvents with varying polarities, including ethanol, n-butanol, acetone, ethyl acetate, n-hexane, and petroleum, effectively retain alkaloids. [62][63][64][65][66] As most alkaloids have medium polarity, 29 solvents like ethanol (used in the soxhlet method) and acidic ethyl acetate solution (used in the maceration B method) are ideal for extracting alkaloids, penetrating deeper and releasing more extractable compounds. This explains the higher yields obtained for soxhlet and maceration B methods, which may also explain the low values obtained by maceration A and refluxing methods, since a high polarity organic solvent as methanol was applied.…”

Section: Alkaloids Detectionmentioning

confidence: 99%

Alkaloids from Marrubium vulgare L.: Antioxidant and Anti-Inflammatory Activities as a Function of Extraction Methods

2023

TJNPR

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The main objective is to determine the most suitable extraction technique for maximizing alkaloid yield and unlocking their potent biological activities. Extraction parameters, including yield, antioxidant activity, and anti-inflammatory activity, will be meticulously assessed. This study's findings will contribute to understanding the alkaloid profile of Marrubium vulgare L leaves and facilitate the development of effective extraction techniques for obtaining high-quality alkaloidrich extracts. Material and Method Chemicals and plant materialThe glassware used was purchased from Pyrex. Solvents (methanol, ethanol, hexane, chloroform, ethyl acetate, and diethyl ether) were purchased from Honeywell Fluka. Chemicals and reagents (Mayer's reagent, iron chloride, sodium hydroxide, ammonia, hydrochloric acid, sulfuric acid, sodium bicarbonate, sodium phosphate, ammonium molybdate, ammonium hydroxide, potassium ferricyanide, trichloroacetic acid, ascorbic acid, lithium chloride, Gel filtration for chromatography Sephadex G-50, aspirin, and formol) were purchased from Sigma-Aldrich (Casablanca, Morocco). Extracts concentration was done using a rotary evaporator (BUCHI, Rotavapor R-100, Germany), and optical density measurements were performed on Ultraviolet/Visible spectrophotometer (Shimadzu UV-1600 PC UV, Japan). Molecular structures and physicochemical data were obtained from PubChem and SwissADME programs (https://pubchem.ncbi.nlm.nih.gov/, http://www.swissadme.ch/). Plant material used consists of Marrubium vulgare L leaves, which were collected during February and March 2021 in the Fez-Meknes region and were identified by Dr. Chaimae Rais in The National Agency for Medicinal and Aromatic Plants, Taounate, Morocco (Document no. 075/2021). The study was conducted at Human Pathology, Biomedicine and Environment Laboratory, in the Faculty of Medicine and Pharmacy (34.00612274141898, -4.964672169974484).

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Section: Alkaloids Detectionmentioning

confidence: 99%

Alkaloids from Marrubium vulgare L.: Antioxidant and Anti-Inflammatory Activities as a Function of Extraction Methods

2023

TJNPR

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“…Ocimum basilicum L. (Basil) is a plant that has a place with the family Labiatae and has demonstrated its capability to help deflect a few ailments in different nations. [9] The crucial oil from european basil contains excessive concentrations of linalool and methyl chavicol (estragole), in a ratio of about 3:1. [10] Different elements consist of: 1,8-cineole, eugenol, and myrcene, amongst others.…”

Section: Introductionmentioning

confidence: 99%

Synergism effect of iron nanoparticles with Ocimum Basilicum L. on breast cancer cell

Alasheqi

Zainulabdeen

2022

ijhs

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Breast cancer is the second leading cause of cancer deaths among women. The development of breast cancer is a multi-step process involving multiple cell types, and its prevention remains challenging in the world. Early diagnosis of breast cancer is one of the best approaches to prevent this disease. In some developed countries, the 5-year relative survival rate of breast cancer patients is above 80% due to early prevention. For people presenting without metastatic disease, therapeutic goals are tumor eradication and preventing recurrence. Ocimum basilicum L. (Basil) is a plant that has a place with the family Labiatae, also basil leave have activities intense cancer prevention agents, curbs aging, is an anticancer, antiviral, and has antimicrobial properties. This study aimed to determine effect of nanotechnology with basil as synergism effect on breast cancer cell also showing the side effect of treatment on normal cells. In this work breast cancer cells (MDA and MCF7) was treated with Iron nanoparticle that prepared by Cold Atmospheric Plasma (CAP) and Ocimum Basilcum L. (Basil) as synergism effect on the cells.

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Thermal Analysis of Sclerotium of <i>Pleurotus tuber-regium</i> (osu) for Effective Drying

Gbasouzor¹,

Ileleji²

2023

WJET

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Thermal drying could lead to the deterioration of substance which affect its nutraceutical and chemical properties. Hence, thermal stability of substance is necessary in course of its drying to acertain the degree of temperature it will be subjected to. In this research, sclerotium of Pleurotus tuberregium is subjected to thermogravimetric analysis, differential thermal analysis and differential scanning calorimetry. Both thermogravimetric analysis and differential thermal analysis were conducted from ambient temperature to 1000˚C at a rate of 20˚C/min constant heating rate, while differential scanning calorimetry was conducted from ambient temperature to 400˚C at a rate of 10˚C/min constant heating rate. Besides, the oxides contents of sclerotium of Pleurotus tuberregium were determined using x-ray fluorescence analysis and the mircostruture was determined with scanning electron microscopy. It was discovered that complete dehydration of the sample ended at about 110.38˚C and oxidation reaction occurred between 233.42˚C to 373.82˚C with release of heat by the sample. Sclerotium of Pleurotus tuber-regium is thermal stable up to 233.42˚C with decompostion of steroid which is its second major component at about 400˚C to 480˚C. The x-ray fluorescence analysis of sclerotium of Pleurotus tuber-regium revealed that Na 2 O, MgO, SiO 2 , Al 2 O 3 , and Fe 2 O 3 are the major compound and SEM analysis showed that it is a solid with amorphous structure having some fibrous skeleton. This study revealed that sclerotium of Pleurotus tuberregium could be dried to minimal moisture content without the deterioration of its nutritional and medinicnal properties.

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Phytochemical and Toxicological Properties of Sclerotium from the Edible Fungus - Pleurotus tuber-regium

Cited by 3 publications

References 7 publications

Alkaloids from Marrubium vulgare L.: Antioxidant and Anti-Inflammatory Activities as a Function of Extraction Methods

Alkaloids from Marrubium vulgare L.: Antioxidant and Anti-Inflammatory Activities as a Function of Extraction Methods

Synergism effect of iron nanoparticles with Ocimum Basilicum L. on breast cancer cell

Thermal Analysis of Sclerotium of <i>Pleurotus tuber-regium</i> (osu) for Effective Drying

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Phytochemical and Toxicological Properties of Sclerotium from the Edible Fungus - Pleurotus tuber-regium

Cited by 3 publications

References 7 publications

Alkaloids from Marrubium vulgare L.: Antioxidant and Anti-Inflammatory Activities as a Function of Extraction Methods

Alkaloids from Marrubium vulgare L.: Antioxidant and Anti-Inflammatory Activities as a Function of Extraction Methods

Synergism effect of iron nanoparticles with Ocimum Basilicum L. on breast cancer cell

Thermal Analysis of Sclerotium of &lt;i&gt;Pleurotus tuber-regium&lt;/i&gt; (osu) for Effective Drying

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Thermal Analysis of Sclerotium of <i>Pleurotus tuber-regium</i> (osu) for Effective Drying