Phytochemical, Antioxidant, Antihyaluronidase, Antityrosinase, and Antimicrobial Properties of Nicotiana tabacum L. Leaf Extracts

Prommaban, Adchara; Kheawfu, Kantaporn; Chittasupho, Chuda; Sirilun, Sasithorn; Hemsuwimon, Kirachuda; Chaiyana, Wantida

doi:10.1155/2022/5761764

Cited by 10 publications

(10 citation statements)

References 43 publications

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“…In treatment 0 mL/L, all plants were infected with the virus, while 4 mL/L. This is due to the presence of nicotine and alkaloids in tobacco extract, which function to repel insects (Prommaban et al, 2022), including Bemisia tabaci and Thrips sp. which have potential as virus vectors.…”

Section: Resultsmentioning

confidence: 99%

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The effect of tobacco leaf extract dosage on the development of virus disease in curly chili

Haryuni,

Priyadi

2024

J Trop Plant Pests Dis

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Curly chili is a horticultural product with high nutritional value, greatly demanded as a distinctive complement or flavoring for dishes due to its unique taste and aroma. Despite the increasing demand for chilies, production has not followed suit, mainly due to disruption caused by viruses transmitted by Bemisia tabaci and Thrips sp. This study aimed to investigate the effect of tobacco extract on the growth and development of viral diseases in curly chili. Conducted at Kwangsang Village, Jumapolo District, Karanganyar Regency, from September to December 2021, the research was designed using a completely randomized block design, with treatment doses of tobacco extract at 0 mL/L, 1 mL/L, 2 mL/L, 3 mL/L, and 4 mL/L, labeled J0, J1, J2, J3, and J4, respectively. The results indicated that the variabels, i.e. plant height, number of leaves, number of fruits, and fruit weight per plant, were significantly affected by the tobacco extract. Similarly, the disease incidence and severity of viral infection were significantly influenced by the tobacco extract application. The yield decrease in curly chili was attributed to virus infection by Bemisia tabaci and Thrips sp., which caused chlorosis and mosaic symptoms on the leaves. Although the affected plants did not die, they experienced a yield reduction. The application of tobacco extract significantly reduced the percentage of incidence and severityof virus infection on curly chili. The highest disease incidence was 35.42% (J0) and disease severity was 70.92% (J0), while the lowest disease incidence was 14.58% (J4) and disease severity was 20.58% (J4).

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Section: Resultsmentioning

confidence: 99%

“…which have potential as virus vectors. Tobacco has also contain chlorogenic acid, a phenolic compound with antioxidant properties and insect-fighting abilities (Prommaban et al, 2022).…”

Section: Resultsmentioning

confidence: 99%

The effect of tobacco leaf extract dosage on the development of virus disease in curly chili

Haryuni,

Priyadi

2024

J Trop Plant Pests Dis

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“…The validation could lead to the discovery of new bioactive principles that could be of future importance in the management of dog bites and related health challenges. (Rawat & Mali 2013;Ameya et al 2017;Omara et al 2020) antioxidant, antistress, antiviral, carcinogenic, antinociceptive, antioxidant, antiaging, anti-hyaluronidase (Rawat & Mali 2013;Ameya et al 2017;Prommaban et al 2022) nicotine, solanesol, malic and citric acid, phenolics, alkaloids, terpenoids, steroids (Rawat and Mali 2013;Ameya et al 2017;Prommaban et al 2022)…”

Section: Discussionmentioning

confidence: 99%

Medicinal plants used in the traditional management of dog bites by herbalists in Eastern, Western, and Central Uganda

Mukasa,

Ogwang,

Owor

et al. 2023

Ethnobot. Res. App.

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Background: Dog bites arise due to man's casual and tactical association with dogs, and it is a global health challenge. Rural and semi-urban communities are the most affected since accessing conventional post-exposure prophylaxis is nearly a myth. As an alternative, readily available and affordable medicinal plants are used. Indigenous knowledge about such plants is limited to specialized herbalists, and with the continuous modernization of African societies, loss of such knowledge is anticipated if not documented. Therefore, the medicinal plants used to manage dog bites in Eastern, Western, and Central Uganda were documented.Methods: Snowball sampling was used to identify the specialized herbalists. An interview guide was used to collect ethnobotanical data from June 2021 to December 2022. The information collected included; names of plants used, plant parts, methods of preparation, and mode of administration. Descriptive data was analyzed using the relative frequency of citation (RFC) index and informant consensus factor (FIC).Results: A total of 31 medicinal plants, belonging to 20 families and 30 genera were documented, with the majority from family Solanaceae. The most commonly used plants were: Baccharoides lasiopus (O.Hoffm.) H.Rob., Gymnanthemum thomsonianum (Oliv. & Hiern ex Oliv.) H.Rob., Rhoicissus tridentata (L.f.) Wild & R.B.Drumm, Phytolacca dodecandra L'Hér., and Nicotiana tabacum L. Leaves were the most used plant parts. The main mode of preparation was infusion. Oral and topical were the major modes of administration. Herbs obtained from the wild were the most used and the conservation strategy was planting around home compounds and in gardens. RFC was ≤ 0.27, and FIC was ≤ 0.19. Conclusion:Specialized herbalists possess vast indigenous knowledge on the utilization of medicinal plants to manage dog bites in Uganda. However, there is a need for scientific justification of the traditional therapeutic claim, in a bid to find novel bioactive compounds which can act as drug leads for the development of drugs for the treatment of dog bite-related infections.

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“…The A. domesticus extracts were investigated for anti-hyaluronidase activity using a spectrophotometric assay adapted from Prommaban et al [ 101 ]. The results were expressed as IC 50 values representing the concentration of A. domesticus extracts suppressing hyaluronidase activity by 50%.…”

Section: Methodsmentioning

confidence: 99%

Acheta domesticus: A Natural Source of Anti-Skin-Aging Ingredients for Cosmetic Applications

Yeerong,

Chantawannakul,

Anuchapreeda

et al. 2024

Pharmaceuticals

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Acheta domesticus is an edible insect, rich in nutritional value and considered a sustainable protein source. This study aimed to investigate the potential application of A. domesticus extracts for anti-skin-aging purposes. The extracts were prepared by maceration at ambient temperature with 95% ethanol or hexane and maceration in gentle heat (45 °C) with 95% v/v ethanol or DI water. The extracts were examined for total protein, phenolic, and flavonoid contents. Protein molecular weight distribution was analyzed. The safety of the extracts was investigated in terms of irritation and cytotoxicity. Biological activities relevant to the inhibition of skin aging were evaluated, including increasing transforming growth factor-beta 1 (TGF-β1) expression and inhibitory activities on collagenase and hyaluronidase. The aqueous extract from maceration in gentle heat had the highest total protein content (63 ± 1% w/w), total phenolic content (0.48 ± 0.03 mg GAE/g extract), TGF-β1 stimulating activities (33 ± 2 pg/mL), and collagenase inhibition (with a half maximal inhibitory concentration of 26 ± 1 µg/mL) among various extracts investigated. It caused no irritation to the hen’s egg chorioallantoic membrane and showed no cytotoxicity to human dermal fibroblasts and peripheral blood mononuclear cells. Therefore, aqueous A. domesticus extract is proposed as an innovative natural anti-skin-aging ingredient.

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Phytochemical, Antioxidant, Antihyaluronidase, Antityrosinase, and Antimicrobial Properties of Nicotiana tabacum L. Leaf Extracts

Cited by 10 publications

References 43 publications

The effect of tobacco leaf extract dosage on the development of virus disease in curly chili

The effect of tobacco leaf extract dosage on the development of virus disease in curly chili

Medicinal plants used in the traditional management of dog bites by herbalists in Eastern, Western, and Central Uganda

Acheta domesticus: A Natural Source of Anti-Skin-Aging Ingredients for Cosmetic Applications

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