Phytochemical Assessment and Evaluation of the Anti-Oxidant, Anti-Microbial, Anti-Cholesterol, and Anti-Diabetic Activities of Triumphetta Pentandra Methanol Based Green Leaf Extract

Mwalimu, Raphael Jilani; Packirisamy, Azhagu Saravana Babu

doi:10.1007/s10904-023-02749-y

Cited by 4 publications

(1 citation statement)

References 28 publications

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“…Entire issue cover up extended research areas in several branches namely spinach derived carbon dots for emerging sensing applications [18] reported Kaur et al, novel poly(lactic acid)/metal organic framework for composite nanoarchitectonics packging applications [19] reported by Bouider et al, key challenges of incorporating reinforcement materials with the polymer matrix composites for three-dimensional (3-D) printing application [20] reported by Abd-Elaziem et al, nickel dimethylglyoxime/ γ-alumina composites nanoarchitectonics photocatalytic applications [21] reported by Abd El-Baki et al, anti-Oxidant, anti-microbial, anti-cholesterol, and anti-diabetic applications [22]…”

Section: Current Research Trends On Carbon Allotropes By Abdelrazek E...mentioning

confidence: 99%

Novel Functionalized 2D-MOF Integrated Hybrid Nanocomposite for Industrial Practice

Pal

2023

J Inorg Organomet Polym

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A significant amount of research attention has been devoted to the integration of metal-organic frameworks (MOFs) into 2D structures and their derivatives due to their remarkable properties, including high specific surface areas, adjustable pore sizes, and ease of functionalization. Consequently, they offer unique advantages in various fields such as catalysis, energy storage, optoelectronics, switches, and switchable devices. Some of the recent advances in this field are presented in this special issue and are briefly described below.

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Section: Current Research Trends On Carbon Allotropes By Abdelrazek E...mentioning

confidence: 99%

Novel Functionalized 2D-MOF Integrated Hybrid Nanocomposite for Industrial Practice

Pal

2023

J Inorg Organomet Polym

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In Silico and In Vitro Investigation of Phytoconstituents from Flacourtia Jangomas as a Potential Candidate for the Treatment of Type 2 Diabetes Mellitus

Tomar,

Mishra,

Sahoo

et al. 2024

ChemistrySelect

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Flacourtia jangomas is a plant used for centuries in Brazil, China, India, and the Malaya Peninsula to treat conditions such as diabetes, asthma, anaemia, and diarrhoea. Despite its therapeutic and economic benefits, the plant has not been popular among farmers due to its limited yield and lack of knowledge about its potential. Targeting PPARγ agonists is a promising approach for discovering and developing effective drugs to treat type 2 diabetes. Due to the activation of the PPARγ through PPARγ agonists, target genes implicated in inflammation, adipogenesis, lipid metabolism, and glucose metabolism are transcriptionally regulated. This study analysed the curated datasets of F. jangomas to identify the binding conformations of the phytoconstituents with different T2DM targets through molecular docking, molecular dynamics, and ADMET prediction approach. To determine the most favourable binding conformations of phytoconstituents that bind with the PPARγ receptors, density functional theory and principal component analysis were performed. The study reveals that the phytoconstituents of F. jangomas can act as PPARγ agonists and could be used to design and optimise the potential antidiabetic agents inspired by natural products. These findings provide a promising approach towards developing effective antidiabetic drugs.

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Terpenoids and Fatty Acid Esters from Underutilized Tiliaceae Shrub Exhibit In Silico Bioactivity and Protein Targets

Jilani,

Packirisamy

2023

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Phytochemical Assessment and Evaluation of the Anti-Oxidant, Anti-Microbial, Anti-Cholesterol, and Anti-Diabetic Activities of Triumphetta Pentandra Methanol Based Green Leaf Extract

Cited by 4 publications

References 28 publications

Novel Functionalized 2D-MOF Integrated Hybrid Nanocomposite for Industrial Practice

Novel Functionalized 2D-MOF Integrated Hybrid Nanocomposite for Industrial Practice

In Silico and In Vitro Investigation of Phytoconstituents from Flacourtia Jangomas as a Potential Candidate for the Treatment of Type 2 Diabetes Mellitus

Terpenoids and Fatty Acid Esters from Underutilized Tiliaceae Shrub Exhibit In Silico Bioactivity and Protein Targets

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