Phytochemical characterisation andin vivoantilithiatic activity of the stems ofCaesalpinia bahamensis(Brasilete)

Abstract

Phytochemical characterisation and in vivo antilithiatic activity of the stems of Caesalpinia bahamensis (Brasilete) Natural product research / UNESCO -

In Vitro Synergistic Inhibitory Effects of Plant Extract Combinations on Bacterial Growth of Methicillin-Resistant Staphylococcus aureus

“…Therefore, it is important to identify compounds involved in a specific pharmacological action and investigate their interactions with other compounds. Brazilin (Peak 1) and protosappanin B (Peak 2) have been reported as the major compounds in CS [32]. Protosappanin displayed antibacterial activities with MIC at 128 μg/mL against both S. aureus and MRSA [39].…”

“…The chromatograms recorded at different detection wavelengths are presented in Figures S1-S4. For each peak, we tentatively identified five compounds as follows: Peak 2 summarizes detailed information on each compound identified or deduced based on data reported in the literature [31][32][33][34][35][36]. The chemical structures of these compounds are shown in Figure 2.…”

“…For each peak, we tentatively identified five compounds as follows: Peak 1 (Brazilin, observed RT: 2.98 min; formula: C16H14O5; molecular weight: 286.28 g/mol), Peak 2 (Protosappanin B, observed RT: 3.10 min; formula: C16H16O6; molecular weight: 304.30 g/mol), Peak 3 (Liquiritin apioside, observed RT: 4.35 min; formula: C26H30O13; molecular weight: 550.51 g/mol), Peak 4 (Glycyrrhizin, observed RT: 9.48 min; formula: C42H62O16; molecular weight: 822.94 g/mol), and Peak 5 (Catechin, observed RT: 3.07 min; formula: C15H14O6; molecular weight: 290.27 g/mol). Table 2 summarizes detailed information on each compound identified or deduced based on data reported in the literature [31][32][33][34][35][36]. The chemical structures of these compounds are shown in Figure 2.…”