Phytochemical Characterization of Vitex negundo Leaves: a Potent Antiandrogenic and Antioxidant Agent

Sharath, Jayapal; Taj, Rafi Ahmed Shahin; Bhagya, Mahadevaiah

doi:10.20307/nps.2022.28.3.130

Cited by 2 publications

(2 citation statements)

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“…[60] A study conducted by Saklani et al [27] revealed that V. negundo exhibited a notably high phenolic content, amounting to 89.71 mg GAE/g of dry extract weight, along with a substantial flavonoid content of 63.11 mg QE/g of dry extract weight. Moreover, when exploring different extraction methods, Sharath et al [61] reported that the ethanolic extract of V. negundo stood out with the highest total polyphenolic content, measuring at an impressive 1650.55 � 205.51 mg/100 g of the sample. This ethanolic extract significantly outperformed other extraction methods, including cold water (578.23 � 23.57 mg/ 100 g sample), hot water (177.71 � 59.79 mg/100 g sample), and petroleum ether (110.70 � 32.86 mg/100 g sample) extracts, all of which exhibited relatively higher total polyphenol content.…”

Section: Phytochemical Constituents Of V Negundomentioning

confidence: 99%

“…revealed that V. negundo exhibited a notably high phenolic content, amounting to 89.71 mg GAE/g of dry extract weight, along with a substantial flavonoid content of 63.11 mg QE/g of dry extract weight. Moreover, when exploring different extraction methods, Sharath et al [61] . reported that the ethanolic extract of V. negundo stood out with the highest total polyphenolic content, measuring at an impressive 1650.55±205.51 mg/100 g of the sample.…”

Section: Introductionmentioning

confidence: 99%

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Chemical Diversity and Medicinal Potential ofVitex negundoL.: From Traditional Knowledge to Modern Clinical Trials

Sharma,

Radha,

Kumar

et al. 2023

Chemistry & Biodiversity

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In recent times, there has been a resurgence of interest in V. negundo, with numerous ongoing clinical investigations exploring its therapeutic potential and the development of formulations derived from its bioactive constituents. Moreover, the market availability of homoeopathic medicines containing V. negundo highlights its enduring popularity. This review article provides a comprehensive analysis of V. negundo, encompassing its phytochemical composition, traditional uses, ethnomedicinal practices, and pharmacological properties. It explores the wealth of knowledge passed down through generations and the potential relevance of this traditional wisdom in modern healthcare. Additionally, the review presents findings from recent clinical trials, shedding light on the efficacy and safety of V. negundo‐based formulations in various therapeutic contexts. Furthermore, the review delves into the emerging application of nanoparticles in V. negundo‐based pharmaceutics, considering their potential to revolutionize drug delivery and formulation techniques. The incorporation of nanotechnology may enhance the bioavailability and targeted delivery of V. negundo's active compounds, further amplifying its medicinal potency. The amalgamation of traditional knowledge and contemporary scientific evidence underscores the relevance of V. negundo in the field of chemistry and biodiversity, paving the way for its continued exploration as a promising source of health‐promoting compounds.

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Section: Phytochemical Constituents Of V Negundomentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%