Phytochemical Composition and Antioxidant Potential of Hyphaene thebaica Fruit

Abstract

The nature and application of medicinal plants in managing complications of various ailments are attributed partly to the presence of different phytochemicals. Oxidative stress due to increased levels of reactive oxygen species is a challenge in the management of such ailments, which might lead to death. This study aimed to determine the phytochemical composition and antioxidant potential of Hyphaene thebaica fruit. The phytochemicals in methanol, aqueous, and ethyl acetate extract were qualitatively determined, followed by quantitation of the ethyl acetate extract as it contains phytochemicals absent in the other extracts. The in vitro antioxidant potential of the ethyl acetate extract of H. thebaica fruit was also determined. The result revealed the presence of alkaloids, saponins, terpenoids, and flavonoids in all the extracts. However, steroids were not detected in the aqueous extract, and glycoside was detected only in the ethyl acetate extract. Flavonoids (5.80±0.20%) were higher than all the other phytochemicals in the ethyl acetate extract, followed by saponins which were present up to 2.50±0.11%, then terpenoids. Glycosides were present in higher amounts compared to steroids. However, alkaloids (0.08±0.05%) were in smaller amounts compared to the other phytochemicals quantified. The antioxidant activity showed a concentration-dependent increase in absorbance of the extract as displayed by the standard (ascorbic acid). The extract had an IC50 of 52.21 µg/mL, significantly (p <0.05) higher than that of the standard (14.10 µg/mL). Due to its phytochemical composition and antioxidant activity, H. thebaica can be used as a medicinal plant.

Phytochemical Composition and Antioxidant Properties of Tambourissa ficus, a Mauritian Endemic Fruit

“…Plants produce phytochemicals during secondary metabolism, which are usually responsible for their extensive pharmacological properties [25]. The phytochemicals detected are consistent with previous studies on the phytochemical content of fruits [26]. The TPC of the different solvent extracts ranged from 2 to 10 mg GAE/g dw (dry weight), as shown in Table 2.…”

Characterization, In Silico Antimalarial, Antiinflammatory, Antioxidant, and ADMET Assessment of Neonauclea excelsa Merr.

“…Some of these phytochemicals include alkaloids, saponins, glycosides, and flavonoids. The antioxidant activities of some of the plants were previously reported (12)(13)(14). Neonauclea excelsa plant is a shrub from the Rubiaceae family found in tropical Africa.…”

“…MDS of DHFRTS and PfHT1 docked with compound II and IV. Note: a) Cluster mobility of II with DHFRTS, b) RMSF of II with DHFRTS, c) Cluster mobility of IV with PfHT1, and d) RMSF of IV with PfHT1.Furthermore, IV showed better docking interaction with MPO, exhibiting lower BA (-7.4 kcal) and Ki (3.71 µM) though VII had higher HPBs(13). The 2D and 3D dock poses of the interactions of DHFRTS and PfHT1 with compounds II and IV, respectively are presented in Figure3, depicting the HB distances and HPB residues.…”

Phytoconstituents, Fourier-Transform Infrared Characterization, and Antioxidant Potential of Ethyl Acetate Extract of Corchorus olitorius (Malvaceae)

“…These phytoconstituents exert their pharmacological activities against oxidative stress-linked diseases via different mechanisms (10)(11)(12). Previous studies reported the in vitro antioxidant activities of different plants demonstrating their radical scavenging activities of the plants (12)(13)(14)(15)(16)(17). Thus, exhibiting their therapeutic potential against oxidative stress.…”