Phytochemical composition of essential oil from seeds of Zingiber roseum Rosc. and its antispasmodic activity in rat duodenum

Prakash, Om; Kasana, Virendra; Pant, A.K.; Zafar, Anjum; Hore, S.K.; Mathela, C. S.

doi:10.1016/j.jep.2006.01.016

Cited by 38 publications

(20 citation statements)

References 5 publications

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“…Several essential oils are reported to exhibit spasmolytic activity (Prakash et al, 2006;Astudillo et al, 2004;El Tantawy et al, 1999;Gamez et al, 1990;Zafra-Polo et al, 1989). Monoterpenes are the major components of these oils.…”

Section: Resultsmentioning

confidence: 99%

Structure and Spasmolytic Activity Relationships of Monoterpene Analogues Found in Many Aromatic Plants

Sousa

Júnior

Andrade

et al. 2008

Zeitschrift Für Naturforschung C

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Rotundifolone, a monoterpene isolated from the essential oil of the leaves of Mentha ¥ villosa, is a constituent of several essential oils and known to have spasmolytic activity. The present study aimed to investigate the correlation between structure and spasmolytic activity of rotundifolone and its analogues in ileum isolated from guinea-pig. Five of the seven tested analogues were found to have a spasmolytic effect more potent than rotundifolone itself, except for pulegone and (+)-limonene. The comparison between rotundifolone and limonene oxide showed that the absence of the keto group did not decrease the relaxant effect. Comparison of the spasmolytic activity between rotundifolone and (+)-pulegone showed that the absence of the epoxy group did not decrease the relaxation of the ileum. Carvone epoxide was found to be significantly more potent than rotundifolone. The monoterpene (Ð)-carvone produced ileum relaxation and was more potent than its enantiomer (+)-carvone. (+)-Limonene and pulegone oxide showed a similar effect. The study showed that the functional groups and their position at the ring of rotundifolone contributed to the relaxation activity of the ileum. The absence of the oxygenated molecular structure is not a critical requirement for the molecule to be bioactive.

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Section: Resultsmentioning

confidence: 99%

Structure and Spasmolytic Activity Relationships of Monoterpene Analogues Found in Many Aromatic Plants

Sousa

Júnior

Andrade

et al. 2008

Zeitschrift Für Naturforschung C

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“…[8,9] Rhizome oils from other gingers, such as Z. cassumunar (Z. montanum, phenylbutanoids) [10,11] , Z. wrayi var. halabala (transanethole) [12] , Z. ottensii (zerumbone, terpinen-4-ol) [13] and Z. roseum (a-pinene, b-pinene, limonene) [14] from various geographical locations have also been characterized.…”

Section: Introductionmentioning

confidence: 99%

High content of zerumbone in volatile oils of Zingiber zerumbet from southern India and Malaysia

Baby

Dan

Thaha

et al. 2009

Flavour & Fragrance J

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Zerumbone is a sesquiterpene phytochemical with potential anticancer, anti-infl ammatory, anti-HIV and other biological activities, most abundantly found in Zingiber zerumbet (L.) Smith. Previous studies reported 12.6-73.1% of zerumbone in Z. zerumbet rhizome oils from various geographical locations. In a careful review of the literature, we found that most of the previous gas chromatographic profi ling studies on volatile oils of Z. zerumbet were inadequate, since they were based on poor identifi cation and quantifi cation procedures and also on single-sample data. In this study, we report the chemical profi les

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“…The essential oils were isolated from 100 g of ground fruits by hydrodistillation for 3 h, using a Clevenger-type apparatus, extracted with Et 2 O, and dried (anh. Na 2 SO 4 ) according to Prakash et al [35].…”

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confidence: 99%

Myrtus communis Berry Color Morphs: A Comparative Analysis of Essential Oils, Fatty Acids, Phenolic Compounds, and Antioxidant Activities

Messaoud

Boussaïd

2011

Chemistry & Biodiversity

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Extracts of mature dark blue and white berries from two Tunisian Myrtus communis morphs growing at the same site were assessed for their essential-oil and fatty-acid compositions, phenolic contents, and antioxidant activities. The GC and GC/MS analyses of the essential oils allowed the identification of 33 constituents. The oils from the dark blue fruits showed high percentages of α-pinene (11.1%), linalool (11.6%), α-terpineol (15.7%), methyl eugenol (6.2%), and geraniol (3.7%). Myrtenyl acetate (20.3%) was found to be the major compound in the oils from white berries. GC Analysis of the pericarp and seed fatty acids showed that the polyunsaturated fatty acids constituted the major fraction (54.3-78.1%). The highest percentages of linoleic acid (78.0%) and oleic acid (20.0%) were observed in the seeds and the pericarps of the white fruits, respectively. The total phenol, flavonoid, and flavonol contents and the concentration of the eight anthocyanins, identified by HPLC analysis, were significantly higher in the dark blue fruits. All extracts showed a substantial antioxidant activity, assessed by the free radical-scavenging activity and the ferric reducing power, with the dark blue fruit extracts being more effective.

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Phytochemical composition of essential oil from seeds of Zingiber roseum Rosc. and its antispasmodic activity in rat duodenum

Cited by 38 publications

References 5 publications

Structure and Spasmolytic Activity Relationships of Monoterpene Analogues Found in Many Aromatic Plants

Structure and Spasmolytic Activity Relationships of Monoterpene Analogues Found in Many Aromatic Plants

High content of zerumbone in volatile oils of Zingiber zerumbet from southern India and Malaysia

Myrtus communis Berry Color Morphs: A Comparative Analysis of Essential Oils, Fatty Acids, Phenolic Compounds, and Antioxidant Activities

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