Phytochemical Constituents and Activities of Morinda citrifolia L.

Krishnaiah, Duduku; Nithyanandam, Rajesh; Sarbatly, Rosalam

doi:10.5772/26094

Cited by 15 publications

(15 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Tannin has received considerable attention in the fields of nutrition, health and medicine, largely due to their physiological activity, such as antioxidant, antimicrobial and anti-inflammatory properties (Killedar and More, 2010;Asquith and Butter, 1986). Saponins protect against hyperglycaemia, hypercholesterolaemia, hypertension (Trease and Evans, 1985), have antibiotic properties and antiinflammatory property and aid healing (Krishnaiah et al, 2009). Phytate has been linked to the prevention of kidney stone, dental decay and calcification of blood vessels.…”

Section: Determination Of Phytochemical Compositionmentioning

confidence: 99%

Effect of <i>Cnidoscolus aconitifolius</i> (Family Euphorbiaceae) Aqueous Leaf Extract on Some Antioxidant Enzymes and Haematological Parameters of High Fat Diet and Streptozotocin Induced Diabetic Wistar Albino Rats

Obichi¹,

Monago²,

Belonwu³

2015

Journal of Applied Sciences and Environmental Management

View full text Add to dashboard Cite

This study was carried out to evaluate the oxidative and haematologic effects of aqueous extract of Cnidoscolus aconitifolius (CA) in high fat diet (HFD) and streptozotocin (STZ) induced diabetes in Wistar albino rats. Diabetes was induced by feeding the rats with HFD that consisted of 20% sucrose and 20% lard for 4 weeks, followed by a single dose intraperitoneal injection of STZ (40mg/kg body weight (BW)). The aqueous leaf extract of CA was administered orally and daily at 400, 600 and 800mg/kg BW from 7days after induction of diabetes and lasted for 12 weeks, while the normal control and diabetic control rats received regular diet and HFD respectively. Metformin (50mg/kg BW) was used as a standard antidiabetic drug. The animals were anaesthetized and sacrificed to obtain blood by cardiac puncture. Preliminary phytochemical analysis of CA showed the content of tannins (5.72±0.00), saponins (12.49±0.021), alkaloids (17.45 ±0.65), flavonoids (23.72 ±0.02), cyanogenic glycosides (0.75 ±0.10) and phytate (1.97 ±0.06). The six vitamins analysed, showed the concentration of vitamin A (5.24mg/kg), vitamin B 3 (1.40mg/kg), vitamin B 6 (37.23mg/kg), vitamin B 12 (15.98mg/kg), vitamin C (382.00mg/kg) and vitamin E (18.28mg/kg). There was significantly (p<0.05) reduced activity of catalase (CAT), significantly (p<0.05) increased level of TBARS, and non significantly (p>0.05) reduced activity of superoxide dismutase (SOD), Packed Cell Volume (PCV) and haemoglobin (Hb) concentration in HFD/STZ induced diabetic rats. CA significantly (p<0.05) increased the SOD and CAT activities, PCV, and Hb concentrations of the treated diabetic rats (TDR) while the TBARS was significantly (p<0.05) decreased compared to the diabetic control (DC). Our findings suggest that CA exhibited reversal effects on these selected oxidative and haematologic markers in rats which were previously damaged by HFD and STZ. © JASEM http://dx.doi.org/10.4314/jasem.v19i2.5

show abstract

Section: Determination Of Phytochemical Compositionmentioning

confidence: 99%

Effect of <i>Cnidoscolus aconitifolius</i> (Family Euphorbiaceae) Aqueous Leaf Extract on Some Antioxidant Enzymes and Haematological Parameters of High Fat Diet and Streptozotocin Induced Diabetic Wistar Albino Rats

Obichi¹,

Monago²,

Belonwu³

2015

Journal of Applied Sciences and Environmental Management

View full text Add to dashboard Cite

show abstract

“…Perbedaan kandungan total fenol antara tepung buah dan tepung daun mengkudu merupakan hal yang mungkin terjadi karena pada dasarnya komposisi senyawa bioaktif yang ada pada keduanya berbeda. Krishnaiah, et al (2012) melaporkan hasil yang berbeda bahwa kandungan total fenol dari daun, buah dan akar mengkudu secara berurutan yaitu sebesar 9,06, 8,73 dan 14,88 mg/g. Assanga, et al (2013) melaporkan bahwa kandungan total fenol buah mengkudu dengan variasi tingkat kematangan dan musim panen berkisar antara 1,426 sampai 3,647 mg/g GAE.…”

Section: Variabel Perlakuan Tepung Buahunclassified

Aktivitas antimikroba dan antioksidan ekstrak tepung daun dan buah mengkudu (Morinda citrifolia)

Kurniawan

2018

JIIP

View full text Add to dashboard Cite

Noni fruit is a medical plant with active compound like antimicrobial and antioxidant that could potentially be used as a feed additive in poultry. This study aimed to determine the activity antimicrobial and antioxidant of noni fuit leave and fruit extract. The method was field experiment arranged in Completely Randomize Design with 3 treatments and 3 replications. The treatments are metanol extract of noni fruit powder, leave noni powder and combination noni fruit and leave powder. The inhibition zone diameter was determined by disc diffusion method, total phenol was determined by Folin-Ciocalteu method, Flavonoid was determined by Aluminium clorida method and antioxidant activity by DPPH (1,1-Diphenyl-2picrylhydrazyl) method. The results showed that noni powder ex-tract had significantly effect (P<0.01) in inhibition of Lactic Acid Bacteria and Escherichia coli. The total phenol of Noni fruit powder is highest approximately 1.67 mg/g GAE. The flavonoid of Noni leave is highest approximately 0.0438 mg/g QE. The DPPH test of Noni fruit is highest approximately 84.03%. It can be concluded that noni fruit extract can be used as an antibacterial and antioxidant in poultry.

show abstract

“…In folk medicine, it is used for treating diverse disorders such as cancer, diabetes, liver diseases, malaria, hypertension, tuberculosis, infection, arthritis and cardiovascular diseases (Ali et al, 2016). Previous studies have shown that the biological activity of M. citrifolia fruit is broad-spectrum including antimicrobial, antitumor, analgesic, antioxidant, anti-inflammatory, anxiolytic, antiarthritic, and antidiabetic activities (Assi et al, 2017;Krishnaiah et al, 2012). In in vivo tests, the ethanolic extract from the leaf and fruit from M. citrifolia, rich in phenolic compounds, showed hypotensive activity (Wigati et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Potent Antifungal Activity of Essential Oil from Morinda Citrifolia Fruits Rich in Short-chain Fatty Acids

Holanda

Bezerra

Ramos

2020

International Journal of Fruit Science

View full text Add to dashboard Cite

The fruit of the Morinda citrifolia species popularly known as "noni" has been widely used in folk medicine for diverse therapeutic purposes including in the treatment of infectious diseases. Given this, we tested the essential oil from M. citrifolia fruits obtained by hydrodistillation against fungi and bacteria. The oil was rich in short-chain fatty acids: octanoic acid (38.7%) and hexanoic acid (20.0%) were identified as the major constituents after analysis of oil by GC/MS. The oil showed antimicrobial activity against all the microorganisms tested, mainly against fungi Candida albicans and C. utilise with minimal inhibitory concentration of 39 and 78 μg.mL −1 , respectively. The antimicrobial potential of the oil was drastically reduced after it was subjected to the esterification reaction, indicating that the carboxyl group is responsible for the strong oil activity.

show abstract

Phytochemical Constituents and Activities of Morinda citrifolia L.

Cited by 15 publications

References 50 publications

Effect of <i>Cnidoscolus aconitifolius</i> (Family Euphorbiaceae) Aqueous Leaf Extract on Some Antioxidant Enzymes and Haematological Parameters of High Fat Diet and Streptozotocin Induced Diabetic Wistar Albino Rats

Effect of <i>Cnidoscolus aconitifolius</i> (Family Euphorbiaceae) Aqueous Leaf Extract on Some Antioxidant Enzymes and Haematological Parameters of High Fat Diet and Streptozotocin Induced Diabetic Wistar Albino Rats

Aktivitas antimikroba dan antioksidan ekstrak tepung daun dan buah mengkudu (Morinda citrifolia)

Potent Antifungal Activity of Essential Oil from Morinda Citrifolia Fruits Rich in Short-chain Fatty Acids

Contact Info

Product

Resources

About