Phytochemical constituents, antimicrobial and antioxidant activities of Kumaun Himalayan Hoop Pine bark extract

Kumar, Pankaj; Sati, S. C.; Khulbe, Kapil; Pant, Prabha; Tripathi, Amrendra Nath; Sarvendra, Kunwar

doi:10.1080/14786419.2020.1851217

Cited by 4 publications

(3 citation statements)

References 20 publications

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“…The other identified steroid, stigmasta-5,24(28)-dien-3-ol, (3β,24Z), which was present at the highest level among the compounds in the plant, has been reported as an antioxidant [28]. Androstan-17-one, 3-ethyl-3-hydroxy-,(5alpha) is also an identified steroid with antioxidant properties [21]. The detected isoflavonoid was a flavone 4'-OH,5-OH,7-di-O-glucoside with antioxidant and anticancer properties [29,30].…”

Section: Discussionmentioning

confidence: 99%

Phytochemical Analysis and Profiling of Antioxidants and Anticancer Compounds from Tephrosia purpurea (L.) subsp. apollinea Family Fabaceae

2023

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Tephorosia purpurea subsp. apollinea was extracted with methanol and n-hexane to obtain sub-fractions. The chemical compounds identified with GC-MS and HPLC in T. purpurea subsp. apollinea extracts showed antioxidant and anticancer properties. The antioxidant and anticancer activities were investigated using DDPH and ABTS assays, and MTT assay, respectively. Stigmasta-5,24(28)-dien-3-ol, (3 β,24Z)-, 9,12,15-octadecatrienoic acid methyl ester, phytol, chlorogenic acid, and quercetin were the major chemical compounds detected in T. purpurea subsp. apollinea. These compounds possessed antioxidant and anticancer properties. The methanol extract showed antioxidant properties with DDPH and ABTS radical scavenging of 84% and 94%, respectively, relative to ascorbic acid and trolox. The anticancer effects of T. purpurea subsp. apollinea against the cancer cell lines MCF7 (IC50 = 102.8 ± 0.6 μg/mL), MG63 (IC50 = 118.3 ± 2.5 μg/mL), T47D (IC50 = 114.7 ± 1.0 μg/mL), HeLa (IC50 = 196.3 ± 2.3 μg/mL), and PC3 (IC50 = 117.7 ± 1.1 μg/mL) were greater than its anticancer effects against U379 (IC50 = 248.4 ± 7.5 μg/mL). However, it had no adverse effects on the normal cells (WI38) (IC50 = 242.9 ± 1.8 μg/mL). Therefore, the major active constituents presented in T. purpurea subsp. apollinea can be isolated and studied for their potential antioxidant and anticancer effects against breast, cervical, and prostate cancers and osteosarcoma.

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Section: Discussionmentioning

confidence: 99%

Phytochemical Analysis and Profiling of Antioxidants and Anticancer Compounds from Tephrosia purpurea (L.) subsp. apollinea Family Fabaceae

2023

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“…Some components detected in the EO of E. fasciculosa have been reported for their antioxidant activity: α-phellandrene [ 88 ], aromadendrenes [ 89 ], viridiflorene [ 90 ], and spathulenol [ 91 ].…”

Section: Discussionmentioning

confidence: 99%

“…Our EO from E. stoatei was characterized by some components known for their antioxidant properties, such as eucalyptol, α-pinene, eucalyptol, aromadendrene, and viridiflorene [ 90 ].…”

Section: Discussionmentioning

confidence: 99%

Essential Oil Composition, Antioxidant Activity and Leaf Micromorphology of Five Tunisian Eucalyptus Species

et al. 2023

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Eucalyptus species have been widely employed in the projects of reforestation in Tunisia. Although their ecological functions are controversial, these plants are indeed important to counteract soil erosion, and represent a fast-growing source of fuelwood and charcoal wood. In the present study, we considered five Eucalyptus species, namely Eucalyptus alba, E. eugenioides, E. fasciculosa, E. robusta, and E. stoatei cultivated in the Tunisian Arboreta. The aim was to carry out the micromorphological and anatomical characterization of the leaves, the extraction and phytochemical profile of the essential oils (EOs), and the evaluation of their biological properties. Four of the EOs showed the prevalence of eucalyptol (1,8-cineole) varying from 64.4 to 95.9%, whereas a-pinene predominated in E. alba EO (54.1%). These EOs showed in vitro antioxidant activity, and reduced the oxidative cellular stress as shown by their activity on reactive oxygen species (ROS) production, and modulation of the expression of antioxidant enzymes, such as glutamate-cysteine ligase (GCL) and heme oxygenase-1 (Hmox-1). Moreover, the EOs inhibited the production of nitric oxide (NO), showing anti-inflammatory activity. The data collected suggest that these EOs may be considered a promising therapeutic strategy for inflammation-based diseases and may represent an additional value for the economy of Tunisia.

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Characterization of chitosan film incorporated pine bark extract and application in carp slices packaging

Wang,

Yin,

Cong

et al. 2024

International Journal of Biological Macromolecules

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Phytochemical constituents, antimicrobial and antioxidant activities of Kumaun Himalayan Hoop Pine bark extract

Cited by 4 publications

References 20 publications

Phytochemical Analysis and Profiling of Antioxidants and Anticancer Compounds from Tephrosia purpurea (L.) subsp. apollinea Family Fabaceae

Phytochemical Analysis and Profiling of Antioxidants and Anticancer Compounds from Tephrosia purpurea (L.) subsp. apollinea Family Fabaceae

Essential Oil Composition, Antioxidant Activity and Leaf Micromorphology of Five Tunisian Eucalyptus Species

Characterization of chitosan film incorporated pine bark extract and application in carp slices packaging

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