Phytochemical Evaluation of Anti-Inflammatory Activity of Different Solvents Extracts of Ixora javanica Flowers

Yerragunta, Vishwanadham; Sunitha, D.

doi:10.4172/2329-6836.1000219

Cited by 5 publications

(4 citation statements)

References 5 publications

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“…The lovely red-blooming plant Ixora javanica , which belongs to the Rubiaceae family, is noted for having a lot of flavonoid chemicals in it, notably in its flowers. Studies on I. javanica ’s phytochemistry revealed the presence of flavonoids such as quercetin, formononetin, and anthocyanin (Dontha et al 2015 ; Vishwanadham et al 2016 ). Indrianingsih et al ( 2021 ) used G. mangostana extract as a dye source and Ixora javanica leaves as a natural mordant to color cotton fabrics and reported that the dyed fabrics showed antibacterial properties, and colors in orange, brown, and green tones were obtained.…”

Section: Mordant Agentsmentioning

confidence: 99%

Bio-mordants: a review

Benli

2024

Environ Sci Pollut Res

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Due to the increasing pressure on environmentally friendly approaches and sustainable production processes, the textile dyeing industry has focused on natural colorants. Thus, the use of bio-mordants, which are biological materials, has become widespread as an alternative to metal salts, most of which are non-ecological, used in the application processes of natural colorants. In natural dyeing, dyers want to use mordant substances in the dyeing processes in order to both expand the color spectrum and improve the fastness properties. Conventional metal salts used in natural dyeing are made up of metallic ions, which, when released into the environment as wastewater effluent at the end of the dyeing process, cause major damage to the ecosystem. Many researchers have thought about using mordants derived from natural sources to address the environmental problem. This article is a review of the investigation of natural mordants used instead of metallic mordants in the process of coloring various textile materials with natural dyestuff sources. It has been determined that many substances, most of them herbal materials, are used as mordants. In this review, mordants, except for conventional metal salts, are examined under three main groups for a better understanding. These groups are as follows: (i) natural or bio-mordants, (ii) oil mordants, and (iii) new-generation and non-vegetable-based mordants. Here, researchers will find an overview of the most recent developments in green mordants as well as application techniques for a variety of mordants.

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Section: Mordant Agentsmentioning

confidence: 99%

Bio-mordants: a review

Benli

2024

Environ Sci Pollut Res

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“…Ixora javanica, an attractive red flowering plant that is a member of the Rubiaceae family, is known to contain high levels of flavonoid compounds, especially in its flowers. Phytochemical studies of I. javanica reported the presence of flavonoids such as quercetin, formononetin and anthocyanin [11,12]. Besides flavonoid content, the flowers were also reported to contain many phenolic and terpenoid compounds, which are responsible for many activities, such as antioxidant, anti-tumour, antiinflammatory, hepatoprotective and tyrosinase-inhibiting activities [13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

A green extraction design for enhancing flavonoid compounds from Ixora javanica flowers using a deep eutectic solvent

et al. 2020

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In this study, an environmentally friendly extraction method for flavonoid compound from Ixora javanica , as a new raw material candidate for herbal medicine and cosmetics, was developed. The objectives of the present work were to provide recommendations for the optimal extraction conditions and to investigate the effects of any extraction parameters on flavonoid yields from the I. javanica flower. The extraction process was performed using deep eutectic solvent (DES) (choline chloride and propylene glycol at molar ratio of 1 : 1) and the ultrasound-assisted extraction method. Both single-factor and response surface analyses using three-level and three-factor Box Behnken designs were conducted to obtain the optimum flavonoid concentrations. The results showed that the optimum extraction conditions for total flavonoids featured an extraction time of 40 min, 25% water content in DES and a solid-to-liquid ratio of 1 : 25 g ml −1 . An extract obtained under optimum extraction conditions showed higher total flavonoid yields than an ethanolic extract which was used for comparison. Scanning electron microscope images demonstrated that both of the solvents also showed different effects on the outer surface of the I. javanica flower during the extraction process. In summary, our work succeeded in determining the optimum conditions for total flavonoids in the I. javanica flower using a green extraction method.

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“…It is very well known by the community and has been widely studied for its compounds and biological activities (Kharat et al., 2013). Extract activities reported in previous studies included antioxidant, antitumor, anti-inflammatory, and hepatoprotective effects (Nair et al., 1991; Hemalatha et al., 2012; Dontha et al., 2016; Vishwanadham et al., 2016). Studies have shown that the flower provides the greatest activity compared to the other parts of the plant (Rohini et al., 2012; Dontha et al., 2015).…”

Section: Introductionmentioning

confidence: 99%

“…Various polyphenolics, such as flavonoids and anthocyanins, were found to be the primary extract compounds in the I. javanica flowers (Dontha et al., 2015). Several studies showed that polyphenolics, flavonoid, and anthocyanin compounds were responsible for most of the activity of Ixora flower extracts (Nair et al., 1991; Kharat et al., 2013; Dontha et al., 2015, 2016; Usha et al., 2016; Vishwanadham et al., 2016). Furthermore, polyphenolic, flavonoid, and anthocyanin compounds reportedly exhibit tyrosinase inhibitory activity (An et al., 2008; Chang, 2012; Liang et al., 2014).…”

Section: Introductionmentioning

confidence: 99%

Application and optimization of ultrasound-assisted deep eutectic solvent for the extraction of new skin-lightening cosmetic materials from Ixora javanica flower

Oktaviyanti

Kartini

Mun’im

2019

Heliyon

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The high demand for cosmetics has had a great impact on the development of innovative products in the cosmetic industry. The availability of raw materials has become a common problem in the cosmetic industry. Materials from nature can act as alternative sources, such as Ixora javanica. Several studies have shown the potential of I. javanica as an antioxidant and skin lightening agent. The objectives of the present study were to develop and optimize a green ultrasound-assisted deep eutectic solvent extraction of I. javanica. Eleven deep eutectic solvents were evaluated based on extraction efficiency parameters; that is, flavonoid and anthocyanin yields; the antioxidant and tyrosinase inhibitory activities of the extracts. The combination of choline chloride and propylene glycol (1:1) was shown to be the optimal deep eutectic solvent for I. javanica extraction. The extraction parameters of temperature, extraction time, and solid-to-liquid ratio were also optimized using response surface methodology. The total flavonoid compound obtained was 33 mg quercetin equivalent/g dried sample under the optimum extraction condition (extraction time of 5 min, temperature of 57 °C, solid-to-liquid ratio of 0.02 g/mL). In sum, this work demonstrates the potential of natural deep eutectic solvent as an organic solvent replacement to obtain high quality Ixora javanica extract, which is a potential new source of skin-lightening cosmetic materials.

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Phytochemical Evaluation of Anti-Inflammatory Activity of Different Solvents Extracts of Ixora javanica Flowers

Cited by 5 publications

References 5 publications

Bio-mordants: a review

Bio-mordants: a review

A green extraction design for enhancing flavonoid compounds from Ixora javanica flowers using a deep eutectic solvent

Application and optimization of ultrasound-assisted deep eutectic solvent for the extraction of new skin-lightening cosmetic materials from Ixora javanica flower

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