Phytochemical Investigation and Anti-cancer Activity of Vitex negundo

Jose, B. Edwin; Manikandan, S.; Jebaseelan, S.; Meera, Dr.R.

doi:10.47583/ijpsrr.2021.v66i01.012

Cited by 1 publication

(1 citation statement)

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“…Rose and Cathrine (2011) [36] , reported E. coli and Streptococcus mutans were resistant to three different solvent extracts of V. negundo leaves viz., petroleum ether, dichloromethane and ethanol. They also reported that Klebsiela pneumoniae, Vibrio cholerae, Streptococcus mutans, Eschericia coli have inhibitory activity next only to the Salmonella paratyphi.…”

Section: Discussionmentioning

confidence: 99%

In vitro antimicrobial activity and preliminary phytochemical screening of some plant extracts

Jawalkar¹,

Zambare²,

Kulkarni³

2020

J Pharmacogn Phytochem

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Antimicrobial activity of five solvent extracts of local plants was evaluated in vitro, with four strains of bacteria viz., Salmonella typhi, Escherichia coli, Shigella flexneri (gram -ve), Staphylococcus aureus (gram +ve) and four strains of fungi viz., Alternaria alternata, Penicillium notatum, Aspergillus niger, Penicillium digitatum microorganism. The in vitro antibacterial and antifungal activities were tested by agar disc diffusion method. The most active antibacterial plants were Vitex negundo, Tagetes erecta and antifungal plants were Xanthium strumarium, Vitex negundo and Tagetes erecta, respectively. The significant antimicrobial activities of potent extracts were compared with the standard antimicrobiotics, Ciprofloxacin and Fluconazole for bacteria as well as fungi respectively at 1 mg/ml concentration. Preliminary phytochemical analysis of V. negundo leaf, X. strumarium, M. pruriens, C. bonduc seed and T. erecta flower extracts generally revealed the presence of Alkaloids, Steroids, Terpenoids, Phenols, Saponins, Anthraquinones, Amino acids, Carotenoids, Flavonoids and Tannins at various concentrations. The results obtained in this study suggest that X. strumarium, V. negundo, T. erecta can be used in treating diseases caused by these test organisms.

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Section: Discussionmentioning

confidence: 99%