Phytochemical investigation and potential pharmacologically active compounds of Rumex nepalensis: an appraisal

Abstract

Background Rumex nepalensis, a widely known traditional medicinal plant and is used as the source of medicines and human diet in various communities. Currently, the phytochemical investigation and pharmacological studies of R. nepalensis are of significant research interest. Therefore, the current review is mainly focused on the phytochemical investigation and pharmacological applications of R. nepalensis Main body Various secondary metabolites like emodin, endocrocin, chrysophanol, neopodin, physcion, torachrysone, aloesin, catechin, quercetin, resveratrol, and their derivatives were isolated from root and aerial parts of the plant. Both isolated compounds and extracts from R. nepalensis are reported to have pharmacological activities such as anti-inflammatory, antioxidant, antimicrobial, wound healing, and anti-plasmodial activities Conclusions Different parts of R. nepalensis have ethnomedicinal importance. R. nepalensis is one of the potential sources of pharmacologically active extracts and isolated compounds. In future R. nepalensis can play a vital role for the preparation of modern drugs. Graphical abstract

Biosynthesis of silver nanoparticles using extract of Rumex nepalensis for bactericidal effect against food-borne pathogens and antioxidant activity

“…As demonstrated in FTIR, the high antioxidant properties of Rn-AgNPs might be owing to the occurrence of various types of active molecules adhered on the surfaces of AgNPs as capping agents. In agreement with our results, RLE has been reported to be rich in phenols, flavonoids, anthraquinones, naphthalenes, saponins, stilbene, triterpenoids, anthraquinone glycosides, tannic acid and sterols, saponin and sitosterols (Mei et al, 2009;Raju et al, 2010;Vasas et al, 2015;Gonfa et al, 2021) of promising antioxidant agents. In addition, these active compounds not only play critical roles in the bio-reduction of Ag ions but also can scavenge free radical species through the donation of electrons or hydrogen atoms from the biomolecules attached to AgNPs (Bindu et al, 2019;Kup et al, 2020;Yousaf et al, 2020;Alarjani et al, 2022).…”

“…(Nepal Dock) is one of the medicinal plants with a broad spectrum of therapeutic potencies in traditional medicine systems (Alberto et al, 2016;Jain and Mehata, 2017;Meresa et al, 2017;Shaikh et al, 2018;Gonfa et al, 2021). Phytochemical screening reveals that the R. nepalensis contains numerous constituents namely, amino acids, quercetin, alkaloid, phenols, flavonoids, triterpenoids, stilbene glycosides, tannins, saponins, resveratrol, anthraquinone, vitamin C, cardiac glycoside, sterols, steroids, sitosterols, emodin, endocrocin, chrysophanol, neopodin, physcion, torachrysone, aloesin and catechin (Ghosh et al, 2001;Mei et al, 2009;Kunwar et al, 2010;Liang et al, 2010;Anusuya et al, 2012;Solanki and Dalsania, 2012;Farooq et al, 2013;Wahid et al, 2013;Gonfa et al, 2021). Extracts and metabolites from different parts of the plant species have shown to possess purgative, antioxidant, antifungal, antibacterial, antihistaminic, anticholinergic, antibradykinin, anti-prostaglandin, antipyretic, analgesic, with a diuretic, astringent, anti-rheumatic, antiseptic, anti-allergic and antisnake bite activities (Kumar et al, 2011;Shrestha and Timilsina, 2017;Shaikh et al, 2018;Mohammed et al, 2019;Gonfa et al, 2021;Mohammed et al, 2021).…”

Ethnomedicinal Use, Phytochemistry, and Other Potential Application of Aquatic and Semiaquatic Medicinal Plants

“…Natural products from medicinal plants are known for their various uses, such as treating infectious diseases, biological applications in the industry as ingredients, food additives, and green synthesis of nanomaterials [1,2]. About 500,000 plants worldwide have a promising potential for their medical activities [3][4][5][6]. Great civilizations such as Mesopotamian, Roman, Greek, Inca, Indus valley, Sindhu, Ghati, and Mohanjordo indicated that humans always preferred to live near plants, streams, lakes, and di erent types of water bodies to get their foods and shelters.…”

Isolation of New Constituents from Whole Plant of Salsola imbricata Forssk. of Saudi Origin

“…Plants have been employed in traditional medicine in various forms since antiquity and continue to provide the medicinal world with therapeutic molecules for which no synthetic alternative exists in some circumstances. 1 They have also been shown to have potential applications in areas such as pollution, taxonomy, nutrition, and corrosion prevention. 2 Plants belonging to the genus Salsola (the largest genera in the Amaranthaceae family, formerly known as Chenopodiaceae) are common in the dry regions of the Middle East, Africa, and Europe.…”