Phytochemical investigation, antioxidant and anticholinesterase activities of Ganoderma adspersum

Tel‐Çayan, Gülsen; Öztürk, Mehmet; Duru, Mehmet Emin; Rehman, Mujeeb Ur; Adhikari, Achyut; Türkoğlu, Aziz; Choudhary, M. Iqbal

doi:10.1016/j.indcrop.2015.07.042

Cited by 40 publications

(26 citation statements)

References 43 publications

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“…The obtained extract solved in water: methanol (80:20) and filtered through a 0.20 µm disposable LC filter disk for HPLC-DAD. All analysis conditions were identical to those described in the recent publication [8]. The phenolic compounds were characterized according to their retention times, and UV data were compared with commercial standards.…”

Section: Analysis Of Phenolic Compoundsmentioning

confidence: 99%

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Comparative assessment of phytochemical composition, antioxidant and anticholinesterase activities of two Basidiomycota Truffle Fungi from Turkey

Deveci¹,

Çayan²,

Duru³

et al. 2018

mpj

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ABSTRACT:The aim of the present study was to compare phytochemical composition and biological activities of various extracts of two Basidiomycota truffle collected from Turkey. Analysis of phytochemical compositions in terms of phenolic and fatty acid compositions was determined using HPLC-DAD, GC and GC/MS. Fumaric (10.62, 4.12 µg/g) and protocatechuic acids (2.71, 20.50 µg/g) were identified as the major organic and phenolic acids in Chondrogaster pachysporus and Setchelliogaster tenuipes truffles. Linoleic acid (53.03 %) for C. pachysporus and palmitic acid (38.60 %) for S. tenuipes were found to be the most dominant fatty acids. The extracts were also tested for their antioxidant and anticholinesterase activities. As for antioxidant and anticholinesterase activity results, C. pachysporus truffle showed better activity than S. tenuipes. This work presents the first phytochemical study on C. pachysporus and S. tenuipes truffles and sheds light on their potential usage as the natural source in the food, pharmaceutical, and cosmetic industries.

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Section: Analysis Of Phenolic Compoundsmentioning

confidence: 99%

“…Mushrooms are considered as valuable foods in many culture due to their unique flavor [1], taste [2,3], nutritional properties [4,5] and biological activities [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Comparative assessment of phytochemical composition, antioxidant and anticholinesterase activities of two Basidiomycota Truffle Fungi from Turkey

Deveci¹,

Çayan²,

Duru³

et al. 2018

mpj

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“…In recent years, numerous studies have demonstrated that polysaccharides isolated from P. pini and P. igniarius displayed antioxidant and antitumor activities (Jiang, Yuan, Cai, Jiao, & Zhang, ; Li, Yang, Ma, Yan, & Guo, ; Liu et al, ; Yuan et al, ). G. adspersum , G. lucidum, and G. applanatum belongs to Ganoderma species, which is considered as an important source of bioactive compounds in worldwide (Ferreira et al, ; Tel‐Çayan et al, ). Antioxidant, cytotoxic, antitumor, neurological, antimicrobial effects of G. lucidum polysaccharides, and antioxidant, antitumor effects of G. applanatum polysaccharides have been reported (Cör, Knez, & Hrnčič, ; Ferreira et al, ).…”

Section: Introductionmentioning

confidence: 99%

Structural characterization and determination of biological activities for different polysaccharides extracted from tree mushroom species

et al. 2019

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Chemical composition and structural characterization of polysaccharides of Fomes fomentarius (FF), Fuscoporia torulosa, Ganoderma adspersum, Ganoderma applanatum (GAP), Ganoderma lucidum, Phellinus igniarius, Pleurotus ostreatus (PO), and Porodaedalea pini (PP) tree mushrooms with antioxidant and anticholinesterase activities were determined in this research. Total carbohydrate contents of the polysaccharides were ranged between 65.06 ± 6.76 and 88.27 ± 5.15 µg/mg and total protein contents were ranged between 3.18 ± 0.72 and 6.56 ± 1.25 µg/mg. Galactose, glucose, and mannose were identified as major monosaccharides in all polysaccharides using gas chromatography‐mass spectrometry. FT‐IR analysis showed the characteristic peaks of the polysaccharides and high performance liquid chromatography‐diode array detection was used to determine the molecular weight of the polysaccharides. In β‐carotene–linoleic acid assay FF (IC50: 2.55 ± 0.40 µg/ml) displayed the highest antioxidant activity, whereas GAP indicated the highest antioxidant activity in cupric reducing antioxidant capacity (A0.50:59.90 ± 0.53 μg/ml), ABTS•+ (IC50: 16.62 ± 0.31 μg/ml), and DPPH• (IC50: 45.58 ± 0.21 μg/ml) assays. In cholinesterase inhibitory activity test, PO (56.31±0.0.74%) showed significant inhibitory activity against butyrylcholinesterase enzyme. Practical applications Polysaccharides from mushrooms are the major class of bioactive compounds with various biological activities. Several studies were performed on the biological activity of the polysaccharide extracts from different mushrooms. However, to our knowledge, this is the first report on the chemical composition, structural characterization, antioxidant, and anticholinesterase activities of extracted polysaccharides from studied mushrooms in detail. This investigation shows that polysaccharide extracts obtained from tree mushrooms show a significant bioactivity and these polysaccharides might be used as bioactive natural sources in the pharmaceutical, food, and cosmetic industries.

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“…The phenolic composition analysis was performed using a Shimadzu 20 AT series high‐performance liquid chromatograph (HPLC‐DAD, Shimadzu Cooperation, Japan) on which a chromatographic separation on an Intertsil ODS‐3 reverse phase C18 column (5 µm, 150 mm × 4.6 mm i.d) thermostatted at 40°C was carried out using the analytical conditions in a previously described publication (Tel‐Çayan et al, ). The proposed chromatographic method was validated in terms of linearity, limit of detection (LOD), limit of quantification (LOQ), and repeatability.…”

Section: Methodsmentioning

confidence: 99%

Phenolic profiles, antioxidant, and anticholinesterase activities of three Gloeophyllum species with chemometric approach

Tel‐Çayan

2019

J Food Biochem

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This study’s aim was to determine the antioxidant and anticholinesterase activities of Gloeophyllum odoratum, Gloeophyllum sepiarium, and Gloeophyllum trabeum species with phenolic profiles. The major compound in G. odoratum (101.6 µg/g) and G. sepiarium (92.61 µg/g) mushrooms was fumaric acid, while ferulic acid was found as the main compound in G. trabeum (11.67 μg/g). The methanol extracts of Gloeophyllum species exhibited the highest activity in CUPRAC, DPPH•, β‐carotene‐linoleic acid, and ABTS•+ assays while the n‐hexane extracts showed the highest activity in the metal chelating assay. Also, the methanol extract of G. odoratum (IC50: 32.16 ± 0.28 µg/mL) was found to be highly active than its antioxidant standard α‐tocopherol (IC50: 38.51 ± 0.54 µg/mL) in the ABTS•+ radical scavenging assay. All the studied Gloeophyllum species extracts were found to be moderate inhibitors against AChE, whereas G. sepiarium n‐hexane extract (69.70 ± 1.92%) and G. odoratum n‐hexane extract (58.08 ± 1.36%) exhibited potent BChE inhibitory activity. Practical applications The results of these studies demonstrated that the methanol and the n‐hexane extracts had a potential application as alternative natural products for pharmaceutical, food, and cosmetic industries. In addition, the chemometric analysis by principal component analysis and hierarchical clustering analysis techniques could be used for the classification of the extracts of Gloeophyllum according to their bioactivity results. This is the first comprehensive study on phenolic profiles and bioactivities of G. odoratum, G. sepiarium, and G. trabeum mushroom species.

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Phytochemical investigation, antioxidant and anticholinesterase activities of Ganoderma adspersum

Cited by 40 publications

References 43 publications

Comparative assessment of phytochemical composition, antioxidant and anticholinesterase activities of two Basidiomycota Truffle Fungi from Turkey

Comparative assessment of phytochemical composition, antioxidant and anticholinesterase activities of two Basidiomycota Truffle Fungi from Turkey

Structural characterization and determination of biological activities for different polysaccharides extracted from tree mushroom species

Phenolic profiles, antioxidant, and anticholinesterase activities of three Gloeophyllum species with chemometric approach

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