Phytochemical investigations of Vernonia galamensis seeds

Fiseha, Ashebir; Tadesse, Mekuria; Tesfaye, Bizuayehu; Bedemo, Belete

doi:10.1007/s10600-010-9717-z

Cited by 4 publications

(4 citation statements)

References 14 publications

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“…In Brazil the tribe is represented by around 40 genera and 450 species [1] – [4] . The genus Vernonia Schreb, subtribe Vernoniinae, is one of the largest groups in the Asteraceae family and includes more than 1000 species [5] , [6] . In South America, there are around 350 species that mainly occur in Northern Argentina, Paraguay, Bolivia and Brazil, the later with approximately 200 species [1] – [3] .…”

Section: Introductionmentioning

confidence: 99%

Metabolomics as a Potential Chemotaxonomical Tool: Application in the Genus Vernonia Schreb

et al. 2014

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The taxonomic classification of the genus Vernonia Schreb is complex and, as yet, unclear. We here report the use of untargeted metabolomics approaches, followed by multivariate analyses methods and a phytochemical characterization of ten Vernonia species. Metabolic fingerprints were obtained by accurate mass measurements and used to determine the phytochemical similarities and differences between species through multivariate analyses approaches. Principal component analysis based on the relative levels of 528 metabolites, indicated that the ten species could be clustered into four groups. Thereby, V. polyanthes was the only species with presence of flavones chrysoeriol-7-O-glycuronyl, acacetin-7-O-glycuronyl and sesquiterpenes lactones piptocarphin A and piptocarphin B, while glaucolide A was detected in both V. brasiliana and V. polyanthes, separating these species from the two other species of the Vernonanthura group. Species from the Lessingianthus group were unique in showing a positive response in the foam test, suggesting the presence of saponins, which could be confirmed by metabolite annotation. V. rufogrisea showed a great variety of sesquiterpene lactones, placing this species into a separate group. Species within the Chrysolaena group were unique in accumulating clovamide. Our results of LC-MS-based profiling combined with multivariate analyses suggest that metabolomics approaches, such as untargeted LC-MS, may be potentially used as a large-scale chemotaxonomical tool, in addition to classical morphological and cytotaxonomical approaches, in order to facilitate taxonomical classifications.

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Section: Introductionmentioning

confidence: 99%

Metabolomics as a Potential Chemotaxonomical Tool: Application in the Genus Vernonia Schreb

et al. 2014

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“…galamensis allowed the isolation and identification of 9-β-D-ribofuranosyl-6-aminopurine (54) (Fig.12) (Keita et al 2016b) The seeds of V. galamensis (Cass.) Less contain 40% epoxy oil (trivernolin) (55) (Fig.13), which, when hydrolyzed, yields different fatty acids with a very high content (80%) of vernolic acid (cis-12,13-epoxycis-9-octadecenoic acid) (56) (Fig.14) (Fiseha et al, 2010). Within the four varieties of Ssp.…”

Section: Coumarinsmentioning

confidence: 99%

Ethnobotany, phytochemistry and pharmacological profile of vernonia galamensis (cass.)less: a review

Keïta¹,

Mariko²,

Koné³

et al. 2017

Int j curr adv res

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“…Ninguno de estos compuestos ha sido encontrado previamente en Kañiwa. Por ejemplo, el ácido vernólico es un ácido graso epoxigenado que se ha reportado en semillas de Vernonia galamensis13 . El ácido pinélico, un metabolito derivado del ácido linoleico, ha sido aislado de la especie Salsola tetrandra, un arbusto Ninguno de estos compuestos ha sido encontrado previamente en Kañiwa.…”

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“…El ácido pinélico, un metabolito derivado del ácido linoleico, ha sido aislado de la especie Salsola tetrandra, un arbusto Ninguno de estos compuestos ha sido encontrado previamente en Kañiwa. Por ejemplo, el ácido vernólico es un ácido graso epoxigenado que se ha reportado en semillas de Vernonia galamensis13 . El ácido pinélico, un metabolito derivado del ácido linoleico, ha sido aislado de la especie Salsola tetrandra, un arbusto de la familia Chenopodiaceae14 .…”

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BÚSQUEDA DE BIOMARCADORES PARA LA DISCRIMINACIÓN DE LAS VARIEDADES DE KAÑIWA (Chenopodium pallidicaule Aellen) “CHILLIWA” Y “RAMIS” POR MEDIO DE METABOLÓMICA NON-TARGETED

Rios

Espichán

Ruiz

et al. 2020

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La “kañiwa” (Chenopodium pallidicaule Aellen) es un grano andino muy nutritivo caracterizado por su alto contenido de proteínas y buen perfil de aminoácidos. La diversidad de esta especie viene siendo caracterizada por estudios agro-morfológicos y genómicos, los cuales no son completamente eficientes para discriminar entre las accesiones y variedades. Actualmente se utiliza la metabolómica como una herramienta adicional para la delimitación de especies. En tal sentido, en el presente trabajo se llevó a cabo el análisis metabolómico “non-targeted” de dos variedades de kañiwa (“Ramis” y “Chilliwa”) provenientes del departamento de Puno, Perú. Para el análisis se utilizó la cromatografía líquida de ultra-alta performance acoplada a la espectrometría de masas de alta resolución con analizador Orbitrap (UHPLC-HRMS). Para la identificación de los metabolitos se utilizaron los softwares MSDIAL y MSFINDER. Los perfiles químicos obtenidos fueron resumidos en una sola tabla para su análisis estadístico con el software SIMCA P. El modelo estadístico OPLS-DA permitió la clasificación de ambas variedades de kañiwa y el gráfico S-plot puso en evidencia los principales biomarcadores putativos para la discriminación de ambas variedades. El metabolito delfinidina-O-(6''-O-α-ramnopiranosil-β-glucopiranósido) fue identificado como uno de los principales biomarcadores para la kañiwa “Ramis”.

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Phytochemical investigations of Vernonia galamensis seeds

Cited by 4 publications

References 14 publications

Metabolomics as a Potential Chemotaxonomical Tool: Application in the Genus Vernonia Schreb

Metabolomics as a Potential Chemotaxonomical Tool: Application in the Genus Vernonia Schreb

Ethnobotany, phytochemistry and pharmacological profile of vernonia galamensis (cass.)less: a review

BÚSQUEDA DE BIOMARCADORES PARA LA DISCRIMINACIÓN DE LAS VARIEDADES DE KAÑIWA (Chenopodium pallidicaule Aellen) “CHILLIWA” Y “RAMIS” POR MEDIO DE METABOLÓMICA NON-TARGETED

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