Phytochemical, pharmacological and tissue culture studies of some important species of the genus Barleria L. (Acanthaceae) - a review

Abstract

Ayurvedic sciences helped the early humans to overcome chronic dangerous diseases. There are thousands of varieties of herbs and medicinal plants used to overcome such dreadful diseases. The genus Barleria L. belongs to family Acanthaceae, a medicinally significant group of plants having diversified phytochemicals used for different pharmacological properties. It has been utilized since ancient times for medicinal purposes. It has many plant secondary metabolites such as terpenes, flavonoids, lignins, alkaloids, particularly the iridoid glycosides. The secondary metabolites extracted from Barleria spp. show potential pharmacological activities viz., anti-microbial, anti-inflammatory, anti-oxidant, anti-fertility, anti-arthritic and anti-ulcer activity. In view of these, present review is focused on the phytochemistry, pharmacology and tissue culture studies of some of the important species of the genus Barleria L.

Alternative Approaches for Rheumatoid Arthritis Management: Future Perspective, Herbal, Dietary, Lifestyle, Psychological, Nutritional Intervention and Healthcare

“…Acanthaceaea Leaf Hexadecanoic acid, ethyl 9,12,15octadecatrienoate Methanolic Assist cell mediate immune response [42].…”

Phytochemical Studies on Two Unexplored Endemic Medicinal Plants of India, Barleria terminalis and Calacanthus grandiflorus

“…Extensive literature survey showed that Barleria is medicinally important genus and locally called as Vajradanti ( Banerjee et al, 2012 ). The plant is widely used in the treatment of human diseases like anemia, toothache, cough, fever, asthma, bronchitis, diabetes, insect bites and inflammations ( Banerjee et al, 2012 ; Sudheer and Praveen, 2021 ). Aerial parts and leaves of Barleria are known to be a vital source of iridoids ( Amoo et al, 2011 ; Sudheer and Praveen, 2021 ).…”

“…The plant is widely used in the treatment of human diseases like anemia, toothache, cough, fever, asthma, bronchitis, diabetes, insect bites and inflammations ( Banerjee et al, 2012 ; Sudheer and Praveen, 2021 ). Aerial parts and leaves of Barleria are known to be a vital source of iridoids ( Amoo et al, 2011 ; Sudheer and Praveen, 2021 ). The leaves of the plant are known for flavonoids, saponins, sterols, tannins, and terpenoids.…”

“…In the same way, aerial part contains balarenone, terpenoid, barlerinoside, saponins, flavonoids, phenolics, tannins, steroids, carbohydrates, phytosterols, acetyl-barlerin, β-sitosterol, iridoids and lupulinoside ( Ata et al, 2009 ). This plant contains numerous medicinal properties ( Sudheer and Praveen, 2021 ). On the other hand, there are no reports on the phytochemical or medicinal potential of C. grandiflorus .…”

Phytochemicals and Biological Activities of Barleria (Acanthaceae)

“…Several species of Barleria are known for their medicinal or ornamental values [ 37 , 52 , 53 ]. There have been studies reviewing the traditional, phytochemical and pharmacological properties of specific species of Barleria (e.g., B. lupulina and B. prionitis ) [ 54 , 55 , 56 ], however none have comprehensively reported on species within Barleria using exisiting literature in a clear and concise manner. Therefore, this review is intended to elaborate on only the important and extensively studied species belonging to the genus Barleria , with an emphasis on their biological activities that have been published.…”