Phytochemical Profile and Antibacterial and Antioxidant Activities of Medicinal Plants Used by Aboriginal People of New South Wales, Australia

Akter, Kazi Mahmuda; Barnes, Emma C.; Brophy, Joseph J.; Harrington, David; Elders, Yaegl Community; Vemulpad, Subramanyam; Jamie, Joanne F.

doi:10.1155/2016/4683059

Cited by 35 publications

(50 citation statements)

References 90 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The Phytochemical groups usually responsible for biological activity are polyphonic compounds, quinones, saponins, flavonoids, tannins, coumarins, terpenoids, and alkaloids (Lai & Roy, 2004). These biologically active compounds have potential anti-inflammatory, antibacterial, antifungal, anti-parasitic, antioxidant, and anticarcinogenic properties (Akter et al, 2016).…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Functional, antioxidant, antimicrobial potential and food safety applications of Curcuma longa and Cuminum cyminum

Akbar¹,

Ali²,

Samiullah³

et al. 2019

PAK.J.BOT.

View full text Add to dashboard Cite

Turmeric (Curcuma longa) and Cumin (Cuminum cyminum) seeds are common spices used in foods and are necessary commodity of kitchens. They have known potential in health and pharmacentical industries. In present study, we explored the antibacterial, antifungal, antioxidant and functional properties of turmeric and cumin seeds extracts. The extracts were also used against Escherichia coli in active packaging for pathogen control and food safety. It was found in the study that, phlobatannins, flavonoids, alkaloids and quinon were absent while the coumarin and terpenoids were present in cumin, whereas turmeric was found rich in phlobatannins, flavonoids, alkaloids, terpenoids and quinon except coumarin, which was found absent. The total phenolic contents of cumin and turmeric were estimated as 51.2 mg/g and 20 mg/g of dry weight equivalent to gallic acid. The DPPH radical scavenging activity of 44% and 46% were recorded for cumin and turmeric respectively. The FTIR analysis established the presence of different functional groups preliminary confirmed by chemical analysis. Both cumin and turmeric were found active against a group of pathogenic bacteria including, Salmonella typhi, Pseudomonas aeruginosa, Staphylococcus aurous and Escherichia coli. Enhanced antibacterial activity of cumin was noted compared to turmeric extracts. Both extracts were found active against different fungal species, Mucor mucedo, Aspergillus flavus, Aspergillus niger and Saccharomyces boulardii. Cumin and Turmeric extracts incorporated in alginate-based film for packaging and foodborne pathogens control in meat were found reducing the number of pathogenic bacteria E. coli.

show abstract

Section: Resultsmentioning

confidence: 99%

“…Phytochemical analysis: Different Phytochemical analysis of the methanol extracts of Cumin and Turmeric was conducted using standard procedures and following (Akter et al, 2016;Sofowara 1993;Trease & Evans, 1983;Harborne, 1973).…”

Section: Materials Methodsmentioning

confidence: 99%

Functional, antioxidant, antimicrobial potential and food safety applications of Curcuma longa and Cuminum cyminum

Akbar¹,

Ali²,

Samiullah³

et al. 2019

PAK.J.BOT.

View full text Add to dashboard Cite

show abstract

“…Immunomodulation using different medicinal plants can offer an alternative to conventional treatment for a variety of infections. 1 There are many studies on the effect of U. dioica. The results of Francišković et al (2017) 8 using root and herbal extract of U. dioica shows that root extracts can decrease the thromboxane production in human platelets, while the herb extracts of U. dioica have inhibitory effect toward 12-LOX (lipoxygenase-type enzyme) pathway, and increase the chemokine release from intestinal epithelial cells.…”

Section: Resultsmentioning

confidence: 99%

“…1,2 Phytochemical and biological investigation have demonstrate their antimicrobial, antifungal, antitumor, antioxidant, antimicrobial and immunomodulatory activity. 3,4 Immunomodulation using medicinal plants may provide novel immunomodulatory agents to supplement the present conventional therapy for a variety of diseases.…”

Section: Introductionmentioning

confidence: 99%

“…3,4 Immunomodulation using medicinal plants may provide novel immunomodulatory agents to supplement the present conventional therapy for a variety of diseases. 1,5 Stinging nettle (Urtica dioica, Urticaceae family) is a wild-growing, widespread perennial plant with marked immunomodulatory, antimicrobial, antitumoral, anti-inflammatory, antioxidant, antiviral, activities. 6,7 The chemical composition of stinging nettle shows the presence of vitamins (A, B, B 12 ) acetylcholine, histamine, serotonine, minerals, chlorophyll, salicylic acid, lecithin, carotenoids, flavonoids, sterols and formic acid.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prolonged in vivo Stinging Nettle Treatment Impacts on Functional Capacity of Leukocytes in Immunologically Mature Chickens

Dana¹,

Niculae²,

Páll³

et al. 2018

IJPER

View full text Add to dashboard Cite

Objective:The experiment aimed at establishing the effects of an alcoholic Urtica dioica extract on the in vitro blastogenic response in antigen stimulated, immunologically mature chickens. Materials and Methods: Three equal groups (n=17) of 47 days old, Rock x Cornish chickens were subjected to oral administration of: a) 0.5 ml/chicken/ day of an alcoholic stinging nettle extract (I), b) 0.5 ml/chicken/day alcohol (II, solvent control), and c) 0.5 ml chicken/day water (III-environment control) for seven days. All birds were injected with 0.5 ml/bird of a 5% SRBC suspension (days 0 and 7). Leukocyte numbers (Burker Turk method) and their blastogenic capacity (blast transformation test) were monitored on days 0, 7 and 14. The specific response was evaluated against a SRBC lysate. Student's t-test was used to evaluate the statistical significance of the differences. Results and Discussion: The leukocyte numbers increased to from 18,083.33 ±4,879.81/mm 3 to 42,833.33±7,547.99/mm 3 by day 14. In vitro responses to C. officinalis and E. angustifolia decreased while SRBC response increased in the nettle treated group. Conclusion: The results did not validate the implemented protocol for the alcoholic stinging nettle treatment. Other administration routes, schemes or dosages should be tested to improve the functional capacity of the leukocytes.

show abstract

Exploring the Anti‐Inflammatory Potential of Australian Native Plants Based on their Ethnopharmacological Knowledge

Mathew,

Zhou,

Münch

et al. 2024

Chemistry & Biodiversity

View full text Add to dashboard Cite

Inflammation represents the inherent protective reaction of the human body to various harmful agents and noxious stimuli. Standard anti‐inflammatory therapy including nonsteroidal anti‐inflammatory drugs are associated with several side effects. In the past decades, people rely on medicinal plants for the treatment of inflammation. The traditional utilization of medicinal plants is regarded as a safe, cost‐effective, and broadly accepted approach. In this study, anti‐inflammatory activity of plants traditionally utilized by the D’harawal people in Australia has been assessed in vitro. Eighty Australian native plants were screened based on the Dharawal Pharmacopeia for their inhibitory effect on the nitric oxide (NO) production in lipopolysaccharides (LPS) and interferon (IFN)‐γ stimulated RAW 264.7 murine macrophages for their anti‐inflammatory activity. From the eighty ethanolic extracts screened, seventeen displayed potent NO inhibition with an IC50 recorded below 15 μg/mL. The aim of this review was to utilise the ethnopharmacological knowledge and to correlate the anti‐inflammatory activity of the seventeen plants with either their known or unknown phytochemicals reported in the literature. In doing so, we have created a snapshot of Australian native plant candidates that warrant further chemical investigation associated with their anti‐inflammatory activity.

show abstract

Phytochemical Profile and Antibacterial and Antioxidant Activities of Medicinal Plants Used by Aboriginal People of New South Wales, Australia

Cited by 35 publications

References 90 publications

Functional, antioxidant, antimicrobial potential and food safety applications of Curcuma longa and Cuminum cyminum

Functional, antioxidant, antimicrobial potential and food safety applications of Curcuma longa and Cuminum cyminum

Prolonged in vivo Stinging Nettle Treatment Impacts on Functional Capacity of Leukocytes in Immunologically Mature Chickens

Exploring the Anti‐Inflammatory Potential of Australian Native Plants Based on their Ethnopharmacological Knowledge

Contact Info

Product

Resources

About