Phytochemical profile and <i>In vitro</i> Anti-inflammatory Activity of <i>Anvillea radiata</i> (Coss and Dur) flowers Extracts

Mahdjar, Salha; Bakka, Chahrazad; Dendougui, Hocine; Hadjadj, Mohamed

doi:10.5958/0974-4150.2020.00010.3

Cited by 6 publications

(2 citation statements)

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“…The production of autoantigens in inflammatory diseases may be due to in vivo denaturation of proteins. Mahdjar et al (2020) show conclusively that Anvillea radiata extract has good anti-inflammatory activity in vitro. This could be due to the presence of secondary metabolites contained in this plant that have interesting biological activities (antibacterial, antifungal, anti-inflammatory, anti-cancer, antioxidant, etc.).…”

Section: Anti-inflammatory Activitymentioning

confidence: 78%

Evaluation of The Analgesic and Anti-Inflammatory Activity of The Aqueous Extract of Anvillea radiata from South West Algeria

khadidja

nasser²,

djahida³

et al. 2022

Egyptian Academic Journal of Biological Sciences, B. Zoology

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Anvillea radiata is used in traditional medicine for the treatment of chest colds, indigestion, and gastrointestinal disorders. Our plant has hypoglycaemic, antitumor, anti-inflammatory, and antibacterial activity and is used for the treatment of dysentery.We have investigated the analgesic and anti-inflammatory activity of the aqueous extract of Anvillea radiata. In analgesic activity, we have used mice of the strain NMRI Albinos, weighing between 26 and 38 g (in vivo study). Acetic acid was used to induce writhes in mice, and the evaluation of the analgesic activity shows that the aqueous extract at 150 mg/kg of our plant induces a decrease in the number of abdominal cramps caused by 1% acetic acid. The aqueous extract of our plant has an analgesic effect almost equal to that of Diclofenac; in fact, the latter causes a pain inhibition of 30.28 1.1% and that of Anvillea radiata of 28.71 2.1% for a concentration of 150 mg/ kg. Our results of this research indicated that Anvillea radiata inhibited inflammation, which could explain its use in traditional medicine.

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Section: Anti-inflammatory Activitymentioning

confidence: 78%

Evaluation of The Analgesic and Anti-Inflammatory Activity of The Aqueous Extract of Anvillea radiata from South West Algeria

khadidja

nasser²,

djahida³

et al. 2022

Egyptian Academic Journal of Biological Sciences, B. Zoology

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“…One region that stands out for its rich botanical diversity is Algeria, known for its numerous endemic plant species with unique therapeutic properties [9]. Among the promising Algerian endemic plants are Anvillea radiata (Coss and Dur), commonly known as "Nogd", which has been traditionally used by the local Berber population for its medicinal properties [10]. Studies have shown that this plant has powerful medical benefits thanks to its rich phytochemical composition, including flavonoids, terpenoids, and phenolic compounds [11].…”

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confidence: 99%

Hepatoprotective Effect of Anvillea radiata Aqueous Extract against Carbon Tetrachloride-Induced Injury in Rats

Belakredar,

Boudou,

Taibi

et al. 2024

C. R. Acad. Bulg. Sci.

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The present study aimed to assess the hepatoprotective property of Anvillea radiata aqueous extract (AAE) against carbon tetrachloride (CCl4)-induced liver injury in rats. Twenty rats were divided into four groups: the control group received no treatment; the second group received a 1 ml dose of CCl4 (30%) orally; the third received a 1 ml dose of CCl4 (30%) orally and AAE at a dosage of 40 mg per kilogram of body weight; the fourth group received AAE alone at the same dose. The results indicated that co-exposure to CCl4 and AAE significantly improved hepatic enzyme markers, including alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP), compared to the CCl4-exposed group. Histological examinations demonstrated that AAE preserved the normal architecture of hepatocytes. In conclusion, Anvillea radiata exhibits notable hepatoprotective property against CCl4-induced toxicity in rats.

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Assessment of antioxidant and antiinflammatory activities and acute toxicity of the aqueous extract from a mixture of leaves and flowers of Anabasis articulata (Forssk.) Moq.

Makhlouf,

Bouaziz,

Benazi

et al. 2024

ARCH BIOL SCI BELGRA

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Colometric assays were used to quantify the secondary metabolites obtained by a decoction of the extract of Anabasis articulata (DEAA) flowers and leaves. Antioxidant activity was examined using several methods: total antioxidant capacity, the 2,2-diphenyl-1-picrylhydrazy (DPPH) radical scavenging assay, and the ?-carotene bleaching assay. Single oral doses of 2000 and 5000 mg/kg body weight were administered to albino mice to assess acute toxicity. In vitro antiinflammatory activity was determined using the egg albumin denaturation test, and the in vivo inflammatory effect was assessed utilizing carrageenan, croton oil, and xylene-induced edema tests. Results showed that DEAA contained high amounts of polyphenols, flavonoids, and tannins and exhibited antioxidant activity in all tested assays. DEAA inhibited protein denaturation and did not cause any mortality or adverse effects. Oral administration of 200 mg/kg DEAA significantly reduced the edema induced by carrageenan, croton oil, and xylene. This study highlights the use of Anabasis articulata (Forssk.) Moq. in traditional herbal medicine. It possesses antioxidant activity and can be considered safe for oral consumption; it also has potential beneficial effects in treating diseases associated with inflammation and pain.

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Phytochemical profile and In vitro Anti-inflammatory Activity of Anvillea radiata (Coss and Dur) flowers Extracts

Cited by 6 publications

References 0 publications

Evaluation of The Analgesic and Anti-Inflammatory Activity of The Aqueous Extract of Anvillea radiata from South West Algeria

Evaluation of The Analgesic and Anti-Inflammatory Activity of The Aqueous Extract of Anvillea radiata from South West Algeria

Hepatoprotective Effect of Anvillea radiata Aqueous Extract against Carbon Tetrachloride-Induced Injury in Rats

Assessment of antioxidant and antiinflammatory activities and acute toxicity of the aqueous extract from a mixture of leaves and flowers of Anabasis articulata (Forssk.) Moq.

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