Phytochemical Profile of <i>Andrographis paniculata</i> Extract from Solvent Partition and Precipitation

Chua, Lee Suan; Abdullah, Farah Izana; Azlah, Muhammad Azfar Firdaus

doi:10.1080/22311866.2019.1646671

Cited by 3 publications

(2 citation statements)

References 28 publications

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“…The solvent system with the higher composition of water was chosen since propolis mostly contains phenolic acids and hydrolyzable tannins which are water soluble [ 35 ]. A high percentage of ethanol (60–80%) was usually used as the solvent system to extract polyphenol-rich leaves from plant samples [ 36 , 37 ]. Water is used to soften the structure of raw propolis, whereas ethanol is a favorable solvent for the extraction of phenolic compounds.…”

Section: Resultsmentioning

confidence: 99%

Evaluating Biological Properties of Stingless Bee Propolis

Lim

Chua

Dawood

2023

Foods

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The aim of the present study was to determine the content of phenolics, flavonoids and tannins, as well as the biological functions of propolis extracts from the stingless bee (Heterotrigona itama). The raw propolis was extracted via maceration with ultrasonic pretreatment in 100% water and 20% ethanol. The yield of ethanolic propolis extracts was about 1% higher than its aqueous counterpart. The colorimetric assays showed that the ethanolic propolis extract had about two times higher phenolics (17.043 mg GAE/g) and tannins (5.411 mg GAE/g), and four times higher flavonoids (0.83 mg QE/g). The higher phenolic content had enhanced the antiradical and antibacterial capacities of the ethanolic extract. The propolis extracts significantly exhibited higher antibacterial activity against gram-positive bacteria (Staphylococcus aureus) than gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa). However, aqueous extract was found to have a higher anticancer property based on the viability of lung cancer cells. No cytotoxic effect was observed on normal lung cells as the cell viability was maintained >50%, even the concentration of propolis extracts were increased up to 800 µg/mL. Different chemical compositions of propolis extract would show different bioactivities depending upon the individual applications. The high content of phenolics suggests that the propolis extract could be a natural source of bioactive ingredients for the development of innovative and functional foods.

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Section: Resultsmentioning

confidence: 99%

Evaluating Biological Properties of Stingless Bee Propolis

Lim

Chua

Dawood

2023

Foods

Self Cite

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“…The use of tuned ultrasonic hydro-solvent in an ultrasound-assisted extraction system results in fast extraction time of 10 and 15 min respectively for the extraction of pectin from jack fruit and polyphenols, amino acid and caffeine from green tea which helps to conserve its pharmacological attributes. [107][108][109] Hydro-solvent tuned under the inuence of this green technology especially the ultrasound exhibits no environmental concern as compared to the toxic organic solvents which can contaminate the activity and quality of the extracts. 102,103,107,110 c Alkaloids, volatile oils and terpenes.…”

Section: Effect Of Extraction Techniques On Yield Of Biometabolitesmentioning

confidence: 99%