Phytochemical profiling and seasonal variation of essential oils of three Callistemon species cultivated in Egypt

Gad, Haidy A.; Ayoub, Iriny M.

doi:10.1371/journal.pone.0219571

Cited by 33 publications

(23 citation statements)

References 28 publications

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“…The data presented in Table 1 indicate that this compound is usually present in low concentrations in plants (generally less than 10,000 ppm, i.e., 1%), even in those whose oily fraction has α-terpineol as the main component. Moreover, extraction from natural sources is influenced by the availability of the starting material, and the composition of essential oils suffers from seasonal conditions (Farias et al 2018;Gad et al 2019). This information explains why chemical synthesis is the main method to obtain commercial α-terpineol, even though it is widely found in natural sources.…”

Section: Chemical Synthesismentioning

confidence: 99%

Production, Properties, and Applications of α-Terpineol

Sales

Felipe

Bicas

2020

Food Bioprocess Technol

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α-Terpineol (CAS No. 98-55-5) is a tertiary monoterpenoid alcohol widely and commonly used in the flavors and fragrances industry for its sensory properties. It is present in different natural sources, but its production is mostly based on chemical hydration using α-pinene or turpentine. Moreover, many bioprocesses for the microbial production of α-terpineol via biotransformation of monoterpenes (limonene, αand β-pinenes) are also available in the literature. In addition to its traditional use, αterpineol has also been evaluated in other application fields (e.g., medical), since some biological properties other than aroma, such as antioxidant, anti-inflammatory, antiproliferative, antimicrobial, and analgesic effects, among others, have been attributed to this compound. Therefore, this review presents an original compilation of data regarding the production (extraction directly from nature; chemical synthesis; via biotechnological process), the chemical and biological properties, and the current market and novel applications of α-terpineol to guide further research in this area. Considering the information presented, we believe that αterpineol applications may transcend the flavors and fragrances industry in the future.

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Section: Chemical Synthesismentioning

confidence: 99%

Production, Properties, and Applications of α-Terpineol

Sales

Felipe

Bicas

2020

Food Bioprocess Technol

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“…Essential oil components were elucidated from their mass spectra and retention indices (RIs) relative to a mixture of a homologous series of standard n ‐alkanes (C 8 –C 28 ) injected under the same conditions. These data were compared with NIST‐11, Wiley Registry of Mass Spectral Database and data reported in the literature 6,11–17 …”

Section: Methodsmentioning

confidence: 99%

“…Owing to the complexity of essential oil composition, chemometrics was performed to achieve accurate differentiation and discrimination between various Pinus species. GC–MS and ATR‐IR were previously screened in many studies for their abilities to portray essential oils of different medicinal plants 10,11 . To our knowledge, this is the first comparative to be carried out on the essential oils of different Pinus species cultivated in Egypt by GC–MS and ATR‐IR coupled to chemometrics.…”

Section: Introductionmentioning

confidence: 99%

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Phytochemical discrimination of Pinus species based on GC–MS and ATR‐IR analyses and their impact on Helicobacter pylori

Gad

Al‐Sayed

Ayoub

2021

Phytochemical Analysis

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Introduction The leaves and cones of Pinus plants as well as their essential oils have been used in traditional medicine for the treatment of several ailments. Objectives Phytochemical discrimination of Pinus species and investigation of their anti‐Helicobacter pylori activity in vitro and in silico. Materials and Methods Gas chromatography–mass spectrometry (GC–MS) and attenuated total reflectance infrared (ATR‐IR) metabolic profiling of the essential oils of Pinus species. Principal component analysis (PCA) and hierarchal cluster analysis (HCA) were applied for discrimination and segregation of Pinus species. Results GC–MS revealed the presence of 76 constituents, where monoterpenes represented the major class with the dominance of α‐pinene (72%) followed by β‐pinene (16%) for P. canariensis. β‐Pinene was the dominant component in P. pinea (24%) followed by terpinolene (11%). α‐Pinene (17%) and caryophyllene (12%) were the major components in P. halepensis, while, 3‐carene (33%) and α‐pinene (17%) represented the major constituents of P. roxburghii oil. By applying PCA and HCA on GC–MS and ATR‐IR data analysis, ATR‐IR displayed much better discrimination for Pinus species. The pine oils showed promising inhibitory effects on Helicobacter pylori. Furthermore, in silico molecular modelling was carried out where the calculated free binding energies of phytochemicals identified ranged from −33.71 to −19.67 kcal/mol for urease and −41.18 to −16.57 kcal/mol for shikimate kinase. This suggests favourable binding of pine essential oil components to both enzymes, thus explaining their potential inhibitory activity on H. pylori. Conclusion GC–MS and ATR‐IR based metabolic analyses could discriminate between Pinus species. Pine essential oils can be used as promising therapeutic drugs to protect against H. pylori infection.

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“…The identification of compounds was performed based on their retention indices relative to a homologous series of n-alkanes (C8-C28) injected under the same conditions and matching their mass spectra with National Institute of Standards and Technology (NIST) and Wiley library database as well as literature [19][20][21][22][23]…”

Section: Compounds Identificationmentioning

confidence: 99%

The Effectiveness of Salavadora Persica (Siwak) Petroleum Ether Extract As An Intracanal Medicament Used in Endodontic Therapy: An In Vitro Study

Ayoub¹,

Badr²,

Alghamdi³

et al. 2021

Preprint

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Background: Salvadora persica L. (Siwak) of the family Salvadoraceae has been used for many centuries as oral hygiene tools, particularly in Saudi Arabia. The current study aimed at developing a new root canal medicament based on the extract of Salvadora persica (SP). The antibacterial activity against Enterococcus faecalis was determined compared with the gold standard intracanal medicament, Ca (OH)2. Materials and Methods: Freeze-dried Siwak sticks were extracted with Petroleum ether to yield an oily extract (SPE). GC-MS analysis was carried out to identify SPE components, whereas 32 compounds were identified (89.09%), with main components of benzyl isothiocyanate (BITC) (33.32%) and steroids (34%). Firstly, the consistency of the experimental medicament was accomplished according to ANSI/ADA Specification no 57. SPE assessment as intracanal medicament was conducted through an in vitro assay on 45 single-rooted mandibular premolars inoculated of 5 μL of E. faecalis. Colony-forming units (CFU) were counted before the application of experimental intracanal medicament (CFU-1) and then after seven days of its application (CFU-2). Group I: Siwak extract-based intracanal medicament, Group II positive control group received Ca(OH)2 paste, and Group III: negative control group received no medication. Results: CFU before and after using Siwak based medicament recorded statistically significant reduction (P=0.006) as well as those of Group II when Ca(OH)2 was applied (P=0.01). On comparing both medicaments with Group III, there were significant differences; (P=0.00) and (P=0.007), respectively. Siwak oil extract-based medication proved complete eradication of E. faecalis.Conclusion: SPE has a good potential as an intracanal medicament, besides the cleaning and shaping during endodontic therapy. This finding could be referred to as the high content of BITC bactericidal against pulpal and periodontal pathogens, in synergism with other antimicrobial components, representing 70.71% of SP oil extract.

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Phytochemical profiling and seasonal variation of essential oils of three Callistemon species cultivated in Egypt

Cited by 33 publications

References 28 publications

Production, Properties, and Applications of α-Terpineol

Production, Properties, and Applications of α-Terpineol

Phytochemical discrimination of Pinus species based on GC–MS and ATR‐IR analyses and their impact on Helicobacter pylori

The Effectiveness of Salavadora Persica (Siwak) Petroleum Ether Extract As An Intracanal Medicament Used in Endodontic Therapy: An In Vitro Study

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