Phytochemical Screening and Antioxidant Activity of some Egyptian Medicinal Plants

Sayed, Heba; issa, mohammady; Mahmoud, Magda E.; abdelkader, emad; Ismail, Hamadi A.

doi:10.21608/jmr.2021.83376.1075

Cited by 2 publications

(2 citation statements)

References 19 publications

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“…In another study, lemongrass ethyl acetate extract was found to contain terpenoids, steroids, tannins, saponins, glycosides, phenols, and flavonoids [28] . Lemongrass has the potential to be combined with various antibacterial compounds [29] .…”

Section: Samplementioning

confidence: 96%

Anticaries Potential of Temu Kunci-Serai Ethyl Acetate Extract Combination: In Vitro and Molecular Studies Approach

Priyadi,

Saputra

2023

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Dental caries is one of the problems in dental disorders suffered by many people. There have been many ways of handling such as using temu kunci and lemongrass plants. This study aims to determine the antibacterial activity of caries in vitro and predict the mechanism of action of the bacteria that cause caries Streptococcus mutans. Temu kunci and lemongrass were extracted using ethyl acetate solvent. antibacterial tests against Streptococcus mutans were carried out using diffusion tests with a combination treatment of temu kunci: serai extracts 5% b/v: 5% b/v, 5% b/v: 10% b/v, and 10% b/v: 5% b/v. The positive control used amoxicillin and DMSO as a negative control. Potency as an anticaries drug of drived compound from Temu Kunci and Serai were evaluated by molecular docking using glucosyltransferase (3AIC). The results showed that the combination of temu kunci and serai with concentration 10% b/v: 5% b/v has potential as anticaries against Streptococcus mutans. Molecular studies depicted that Panduratin A, Isopanduratin, and 1,3-O-di-p-coumaroylglycerol have great activity toward 3AIC, respectively. Especially for Panduratin A and Isopanduratin, those compound depicted great and similar binding affinity (-8.4 kcal mol-1) that lower than Acarbose as native ligand (-8.3 kcal mol-1). Furthermore, those compound binding similarity ilustrated activity mechanism similarly with native ligand toward receptor. Additionally, the profiling drug-target interaction suggested Temu Kunci’s derived compounds have great potential as anticaries treatment.

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Section: Samplementioning

confidence: 96%

Anticaries Potential of Temu Kunci-Serai Ethyl Acetate Extract Combination: In Vitro and Molecular Studies Approach

Priyadi,

Saputra

2023

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“…Phytochemical screening was done following standart test tube methods 8 . Extract of samples was used to screen some compounds like alkaloids, flavonoids, saponins, tannins, phenols, steroids, and terpenoids.…”

Section: Phytochemical Screeningmentioning

confidence: 99%

The Phytochemical Profile of Mangifera Rufocostata Kosterm and Its Antioxidant Activity

Sutomo,

Arnida,

Rizki

et al. 2023

Bulletin of Pharmaceutical Sciences. Assiut

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The tandui plant (Mangifera rufocostata Kosterm.) is one of the typical plants of South Kalimantan which belongs to the genus Mangifera. It has the potential as medicine. The local people use boiled water from bark of M. rufocostata to treat diabetes and minor stoke. This study aims to identify compounds and determine the antioxidant activity of leaves and bark ethanol extract M. rufocostata qualitatively and quantitatively. The results of the identification show that ethanol extract of M. rufocostata contains tannins, phenols, flavonoids and saponins. The result of the qualitative antioxidant activity test shows that the ethanol extract of M. rufocostata has an antioksidan activity. The result of quantitative antioxidant acivity test reveals that the leave and bark have IC50 value of 7,614 ppm and 8,254 ppm. Based on this research, it can be concluded that ethanol extract of M. rufocostata from Hulu Sungai Tengah District contains various secondary metabolites such as tannins, phenols, flavonoids, and saponins and have a very strong antioxidant activity.

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Phytochemical Screening and Antioxidant Activity of some Egyptian Medicinal Plants

Cited by 2 publications

References 19 publications

Anticaries Potential of Temu Kunci-Serai Ethyl Acetate Extract Combination: In Vitro and Molecular Studies Approach

Anticaries Potential of Temu Kunci-Serai Ethyl Acetate Extract Combination: In Vitro and Molecular Studies Approach

The Phytochemical Profile of Mangifera Rufocostata Kosterm and Its Antioxidant Activity

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