Phytochemical Screening and Hypoglycemic Effect of Aqueous Blighia sapida Root Bark Extract on Normoglycemic Albino Rats

Saidu, Abubakar Ndaman; Mann, A.; Onuegbu, C. D.

doi:10.9734/bjpr/2012/1056

Cited by 25 publications

(8 citation statements)

References 37 publications

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“…The roots, bark, leaves, capsules and seeds were identified in the treatment of 22 diseases in Benin [2]. Consumption of ackee roots bark extract exerted significant hypoglycemic effect on the normoglycemic albino rats [5]. However, limited information exists on the health beneficial components of the arils.…”

Section: Introductionmentioning

confidence: 99%

Ackee (Blighia sapida) Fruit Arils: Nutritional, Phytochemicals and Antioxidant Properties

Dossou¹

2014

IJNFS

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The limited information on the health and nutritional benefits of edible arils of the ackee (Blighia sapida) tree makes it underutilized in West Africa. This study was to investigate the nutrient content, total phenols, antioxidant activity and phytochemical constituents of freeze and oven dried ackee arils. Phytochemical analysis was done using standard protocol whereas antioxidant activity and total phenol content was determined using the DPPH and Folin-Ciocalteau methods, respectively. The minerals content was determined by means of atomic absorption spectrophotometry. The moisture, crude fat, crude protein, crude fibre, ash, carbohydrate and energy content were in the range of 4.83-5.20%, 51.60-56.66%, 10.94-11.67%, 3.63-3.88%, 8.01-8.56%, 14.41-20.62% and 590.67-614.26 kcal/100g, respectively. The ackee arils also contained appreciable minerals (Ca, P, Mg, Na, K and Zn) with K (425.10-475.71 mg/100g) being the highest while Zn (1.95-2.08 mg/100g) was the least mineral. Phytochemical screening revealed the presence of tannins, saponins and glycosides in the arils. The total phenolic content was 5235.04±103.9 and 5175.38±178.46 mg GAE/100g in oven-dried and freeze-dried samples, respectively. The vitamin C content was 29.6 and 35.7 mg/100 g whereas antioxidant activity was 66.0 and 29.4 % DPPH inhibition (with trolox equivalence of 91.0±9.4 and 40.6±0.6 µM TE/g) in the oven and freeze dried ackee arils, respectively. Drying method had effect on the phytochemicals and antioxidant activity of the ackee flour sample. The findings suggest that ackee aril had considerable total phenols content and antioxidant activity, which implies that the fruit aril has the potential for application in food systems to maintain food quality.

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Section: Introductionmentioning

confidence: 99%

Ackee (Blighia sapida) Fruit Arils: Nutritional, Phytochemicals and Antioxidant Properties

Dossou¹

2014

IJNFS

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“…Tannins hasten the healing of wounds and inflamed mucuous membrane (Okwu et al 2006). The presence of these phytochemicals support the medicinal use of Blighia sapida (Saidu 2012).…”

Section: Discussionmentioning

confidence: 93%

Phytochemical Screening and in vitro Antioxidant Activity of Hydro-Ethanolic Extract of Blighia sapida Stem Bark

Amira¹,

Daramola²,

Oyelade³

2019

JBAH

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Blighia sapida is a plant belonging to the family of Sapindaceae. In this study we aimed to carry out the phytochemical screening of hydro-ethanolic (15%) extract of Blighia sapida stem bark and evaluate its in vitro antioxidant activity. It was found that the hydro-ethanolic extract of Blighia sapida stem bark showed the presence of saponin, flavonoid, alkaloid, phenols and ascorbic acid. It also contains trace elements zinc and selenium. Furthermore it showed some scavenging activity but not as such could be compared with the various standards used except for nitric oxide scavenging activity.

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“…The inhibitory effects of the B. sapida stem bark extract on the α -amylase and α -glucosidase actions may be a result of its phytochemical contents such as polyphenols, tannins, and saponins [ 52 ]. The root extract of B. sapida has been shown to have a hypoglycaemic effect in normoglycemic rats and ameliorate pancreatic β -cell dysfunction [ 53 ]. The phytochemical constituents of the stem bark include cardiac glycosides, saponins, anthraquinones, flavonoids, alkaloids, phlobatannins, and terpenes [ 54 ].…”

Section: Resultsmentioning

confidence: 99%

Medicinal Plants with Prospective Benefits in the Management of Peptic Ulcer Diseases in Ghana

Boakye-Yiadom

Kumadoh

Adase

et al. 2021

BioMed Research International

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Background. The growth or multiplication of harmful microorganisms in addition to harmful human activities has led to many disorders in humans. Consequently, there is a search for medications to treat these disorders. Interestingly, medicines of plant origin are known to be among the most attractive sources of new drugs and have shown promising results in the treatment of various diseases including peptic ulcers. This review, therefore, is aimed at obtaining knowledge on some Ghanaian ethnomedicinal plants used to treat peptic ulcers, their folkloric uses, their phytochemicals, and their antiulcer and related pharmacological activities as well as finding areas for prospective studies.Methods. Published peer-reviewed articles on ethnomedicinal plants used for the management of peptic ulcers in Ghana from 1967 to 2020 were sourced and used for the study. Results. In this review, 13 plants were identified which belong to 10 different families including Sapindaceae, Apocynaceae, and Bignoniaceae. The parts most often used for most preparations were the leaves (53%), followed by stem bark and roots (both having the same percentage of use of 17.6%), the whole plant (5.9%), and the rhizomes (5.9%). Azadirachta indica was the only plant that had undergone some patient studies in addition to animal studies. Conclusion. A discussion of various antiulcer activity studies using ulcer models carried out on selected medicinal plants used for the management of peptic ulcer disease in addition to brief information on their folkloric uses and their phytochemical and other pharmacological properties is presented. These medicinal plants may be used in developing herbal products for the management of peptic ulcer disease.

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Phytochemical Screening and Hypoglycemic Effect of Aqueous Blighia sapida Root Bark Extract on Normoglycemic Albino Rats

Abstract: Aims:To carry out phytochemical screening and investigate hypoglycemic effect of aqueous Blighia sapida root bark extract (ABRE) on normoglycemic Albino rats. Study Design: Extraction and administration of bioactive extract.

Cited by 25 publications

References 37 publications

Ackee (Blighia sapida) Fruit Arils: Nutritional, Phytochemicals and Antioxidant Properties

Ackee (Blighia sapida) Fruit Arils: Nutritional, Phytochemicals and Antioxidant Properties

Phytochemical Screening and in vitro Antioxidant Activity of Hydro-Ethanolic Extract of Blighia sapida Stem Bark

Medicinal Plants with Prospective Benefits in the Management of Peptic Ulcer Diseases in Ghana

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