Phytochemicals content, antioxidant and hypoglycaemic activities of commercial nutmeg mace (<i>Myristica fragrans</i> L.) and pimento (<i>Pimenta dioica</i> (L.) Merr.)

Loizzo, Monica Rosa; Sicari, Vincenzo; Tenuta, Maria Concetta; Leporini, Maria Rosaria; Falco, Tiziana; Pellicanò, Teresa Maria; Menichini, Francesco; Tundis, Rosa

doi:10.1111/ijfs.13178

Cited by 24 publications

(11 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The FRAP assay was utilized as previously described . The FRAP value represents the ratio between the slope of the linear plot for the reduction of the Fe 3+ ‐TPTZ reagent by different extracts compared to the slope of the plot for FeSO 4 .…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Comparative Chemical Composition and Bioactivity of Opuntia ficus‐indica Sanguigna and Surfarina Seed Oils Obtained by Traditional and Ultrasound‐Assisted Extraction Procedures

Loizzo

Bruno²,

Balzano

et al. 2018

Euro J Lipid Sci & Tech

Self Cite

View full text Add to dashboard Cite

This study investigates the seed oils obtained from two different varieties of Opuntia ficus‐indica (Sanguigna and Surfarina) growing in Sicily, Italy. Soxhlet and ultrasound‐assisted extraction procedures are used to obtain the seed oils. The fatty acid profile, γ‐tocopherols, carotenoid content, and the bioactivity in terms of the antioxidant effects (using ABTS, DPPH, FRAP, and β‐carotene bleaching tests), and carbohydrate‐hydrolysing enzyme inhibitory activity (α‐amylase and α‐glucosidase) are determined. The extraction procedure does not significantly affect the fatty acid composition of the oil, but it does affect the tocopherol and carotenoid contents, as well as the antioxidant and inhibitory activities. All the oil samples are rich in polyunsaturated fatty acids, especially linoleic, and oleic acids. Soxhlet extraction proves to be the best extraction procedure to enrich the oils in γ‐tocopherol. Relative antioxidant capacity index (RACI) and global antioxidant score (GAS) analyses are applied to evaluate the antioxidant potential of the Sanguigna variety oil extracted with the Soxhlet apparatus that is shown to be the most active. The same oil also shows the highest α‐amylase inhibitory activity (IC50 value of 40.9 μg mL−1), which is better than that reported for acarbose used as a positive control. Practical Applications: This study is the first to evaluate the effect of oil extraction technologies on the bioactive compound levels and antioxidant and hypoglycaemic activities of cactus pear seed oil, which is a by‐product of fruit processing. The findings will contribute to the valorization of food by‐products. The results provide useful information to select the most valuable technological conditions for oil extraction to preserve the bioactive compounds and the biological activity of the vegetable by‐product extracts, such as seed oil. Cactus pear seed oil obtained by the traditional extraction procedure (Soxhlet) represents a promising source of healthy compounds, particularly of carotenoids and γ‐tocopherol, used not only as antioxidants to preserve lipid components in food preparation but also as functional ingredients due to their hypoglycaemic effect. Effect of extraction procedure on chemical composition, antioxidant potential, and hypoglycaemic activity of cactus pear seed oils.

show abstract

Section: Methodsmentioning

confidence: 99%

“…The α‐glucosidase inhibition was measured as previously described . Both control and samples (at concentrations in the range of 0.01–1 mg mL −1 ) were added to the maltose solution and left to equilibrate at 37 °C.…”

Section: Methodsmentioning

confidence: 99%

Comparative Chemical Composition and Bioactivity of Opuntia ficus‐indica Sanguigna and Surfarina Seed Oils Obtained by Traditional and Ultrasound‐Assisted Extraction Procedures

Loizzo

Bruno²,

Balzano

et al. 2018

Euro J Lipid Sci & Tech

Self Cite

View full text Add to dashboard Cite

show abstract

“…Previous study has reported a lower activity of ME (75.7 µg/ml) when using mace commercial dried powder. 25 The ME was observed to have stronger inhibition than EAE (t = 7.96, p < 0.05). The strong relationship between α-glucosidase inhibitory activity (IC 50 ) and the total phenolic content was previously demonstrated in the literature 26 and gallic acidtype compounds may be responsible for the α-glucosidase inhibitory activity as reported previously.…”

Section: α-Glucosidase Inhibitory Activitymentioning

confidence: 90%

Bioactivities of Methanol and Ethyl Acetate Mace Extracts of Myristica fragrans Houtt

Simamora¹,

Santoso²,

Timotius³

2018

View full text Add to dashboard Cite

Introduction: Myristica fragrans Houtt is used as a spice in Indonesia. This study aimed to scientifically validate the traditional use of mace from M. fragrans. Methods: The mace was extracted with methanol and ethyl acetate, and the chemical composition was analysed by GC-MS. The extracts were evaluated for their antibacterial activities against seven different bacteria based on a well diffusion method, their antioxidant activities based on DPPH radical scavenging assay, and their α-glucosidase inhibitory activities in vitro. Results: Four major components were identified from both extracts: sabinene, methoxyeugenol, myristicin, and elemicin. The methanol extract (ME) had higher methoxyeugenol, myristicin and elimisin levels, whereas sabinene was dominant in ethyl acetate extract (EAE). Both extracts showed good antibacterial activity against S. aureus only. Both extracts showed good antioxidant activities, in which EAE showed stronger activity than ME (IC 50 94 μg GAE/ml and IC 50 162 μg GAE/ml, respectively). Further more, both extracts inhibited α-glucosidase more strongly than the standard acarbose, in which ME (IC 50 7.50 μg GAE/ml) exhibited stronger α-glucosidase inhibitory capacity than EAE (IC 50 10.65 μg GAE/ml). Conclusion:The results suggest that ME and EAE of M. fragrans have biological activities with high potential for pharmacological uses.

show abstract

“…The research on ATR mainly focuses on its antioxidant activity. Some reports suggested that antioxidants can scavenge free radicals and reduce lipid peroxidation, protein peroxidation, and DNA damage of free radicals [ 10 , 11 ]. The studies on the antioxidants in food, plant materials, and TCMs recently attracted increasing attention [ 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

GC-MS Fingerprinting Combined with Chemometric Methods Reveals Key Bioactive Components in Acori Tatarinowii Rhizoma

Liu

Zhang

Xin

et al. 2017

IJMS

View full text Add to dashboard Cite

This present study aims to identify the key bioactive components in acorus tatarinowii rhizoma (ATR), a traditional Chinese medicine (TCM) with various bioactivities. Partial least squares regression (PLSR) was employed to describe the relationship between the radical scavenging activity and the volatile components. The PLSR model was improved by outlier elimination and variable selection and was evaluated by 10-fold cross-validation and external validation in this study. Based on the PLSR model, eleven chemical components were identified as the key bioactive components by variable importance in projection. The final PLS regression model with these components has good predictive ability. The Q2 was 0.8284, and the root mean square error for prediction was 2.9641. The results indicated that the eleven components could be a pattern to predict the radical scavenging activity of ATR. In addition, we did not find any specific relationship between the radical scavenging ability and the habitat of the ATRs. This study proposed an efficient strategy to predict bioactive components using the combination of quantitative chromatography fingerprints and PLS regression, and has potential perspective for screening bioactive components in complex analytical systems, such as TCM.

show abstract

Phytochemicals content, antioxidant and hypoglycaemic activities of commercial nutmeg mace (Myristica fragrans L.) and pimento (Pimenta dioica (L.) Merr.)

Cited by 24 publications

References 30 publications

Comparative Chemical Composition and Bioactivity of Opuntia ficus‐indica Sanguigna and Surfarina Seed Oils Obtained by Traditional and Ultrasound‐Assisted Extraction Procedures

Comparative Chemical Composition and Bioactivity of Opuntia ficus‐indica Sanguigna and Surfarina Seed Oils Obtained by Traditional and Ultrasound‐Assisted Extraction Procedures

Bioactivities of Methanol and Ethyl Acetate Mace Extracts of Myristica fragrans Houtt

GC-MS Fingerprinting Combined with Chemometric Methods Reveals Key Bioactive Components in Acori Tatarinowii Rhizoma

Contact Info

Product

Resources

About