Phytochemistry and Pharmacology of Iris kashmiriana

Abstract

Iris kashmiriana belonging to the family Iridaceae, is found commonly in graveyards in the Kashmir region of India, as well as in some areas of Pakistan. This plant is used as a traditional medicinal plant by different local communities. Ethnopharmacological studies have revealed the presence of isoflavones like isonigricin (1) which is a new isoflavone and isoirisolidone (2) and Irisolidone (3) which were isolated first time from a natural source. This emphasis of this review is to focus on traditional uses, pharmacological uses, as well as phytoconstituents present in this species. But as this species is critically endangered also. By exploring more about this species, it might help in getting this species in the least concern or prevent it from being extinct. Scientific investigation has found that this plant has a lot of pharmacological activities like antimicrobial, antitumor, anthelmintic, immunomodulatory, antiseptic, antioxidant, and also used in cold, flu, malaria, joint pain, anti-inflammation, toothache, etc. This plant contains several constituents, including isoflavones, with pharmacological activities some of them are still not been fully explored yet. In this review, an approach was made to study ethnopharmacology, phytochemistry, and pharmacological investigations, of Iris kashmiriana, which can be explored more, so that people could know more about this plant, and start growing this medicinal plant.