Phytochemistry, bioactivities and future prospects of mulberry leaves: A review

Ma, Guang-Qun; Chai, Xin‐Sheng; Hou, Gui‐Ge; Zhao, Fenglan; Meng, Qingguo

doi:10.1016/j.foodchem.2021.131335

Cited by 97 publications

(50 citation statements)

References 100 publications

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“…The phenols contents of mulberry leaves vary with variety, cultivation, maturation, and processing. The fresh mulberry leaf vegetable had high total polyphenol content of about 4.66 mg GAE/g just after harvest, which was higher than that reported by Ma et al 22 . As expected, the total polyphenol content changes in mulberry leaf vegetable during storage were different between MP20 packaging and CK (Fig.…”

Section: Resultscontrasting

confidence: 64%

Effects of modified atmosphere packaging on the postharvest quality of mulberry leaf vegetable

Yang

Chen

Zeng

et al. 2022

Sci Rep

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Fresh mulberry leaf vegetable is nutritive and becoming popular. However, available preservation technologies are deficient. In present work, the effects of two kinds of modified atmosphere packaging on postharvest quality of fresh mulberry leaf vegetable stored at 4 °C were evaluated. The respiration rate of samples in the modified polyethylene packages (MP20) was 12.88–22.65% lower than that in normal polyethylene packaging (CK). The content of total soluble solids, soluble protein, and total polyphenol in MP20 was less changed than that in CK, and the vitamin C retention was higher as well. Moreover, the lignin content in MP20 was lower than that in CK during storage (19.79% vs 13.38% at day 8), and that was significantly positively related to the polyphenol oxidase and peroxidase activities inhibition. Taken together, a packaging with moderate gas permeability (MP20) is suitable for nutrition maintenance and lignification inhibition of fresh mulberry leaf vegetable during cold storage.

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Section: Resultscontrasting

confidence: 64%

Effects of modified atmosphere packaging on the postharvest quality of mulberry leaf vegetable

Yang

Chen

Zeng

et al. 2022

Sci Rep

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“…These compounds restrict the free radicals, holes, and superoxides, and their concentration is 1 mmol/L. [22]. The photocatalytic activity is improved by the crystallinity of the nanoparticles, as evidenced by a strong peak.…”

Section: Antibacterial Activitymentioning

confidence: 99%

Synthesis and Applications of Green Synthesized TiO₂ Nanoparticles for Photocatalytic Dye Degradation and Antibacterial Activity

Shimi

Ahmed

Wahab

et al. 2022

Journal of Nanomaterials

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Metal oxide photocatalyst is one of the promising photocatalysts in the water remediation process. The present work is aimed at synthesizing the green production of TiO2 (G-TiO2) nanoparticles from mulberry plant extract. Plant phytochemicals serve a different role to produce the nanophase particles. The bioreductant is safer and noxious free compound for synthesizing the G-TiO2 nanoparticles. The synthesized G-TiO2 nanoparticles in anatase phase and their crystallite size of 24 nm were characterized from X-ray diffraction analysis. The Ti-O bonding and plant derivatives and their reduction were confined from FTIR analysis. The wide bandgap of G-TiO2 nanoparticles (3.16 eV) and their optical characterization were captured from UV-DRS analysis. The spherical surface morphology and their Ti and O elemental configurations were characterized from FESEM with EDX technique. The photocatalytic dye degradation was examined against methylene blue dye, and their pseudo-first-order kinetics were evaluated. The cyclic experiments declared their catalytic potential. The bacterial resistance of G-TiO2 nanoparticles was examined against gram-positive and gram-negative bacteria. Hence, the catalytic potential and bacterial stability of G-TiO2 nanoparticles are the powerful candidate for water remediation and biomedical applications.

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“…The different parts of mulberry are rich in flavonoids and exert anti-inflammatory and antioxidative activities, including the root bark, fruits, and leaves [ 14 , 15 ]. Mulberry leaves are a food source for silkworms and used for medicine, human food, and animal husbandry, which have been attributed to its abundant active ingredients and nutritional value [ 16 ]. Their leaves and leaf-derived extracts are also rich in flavonoids that possess anti-inflammatory and antioxidative activities [ 17 , 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

“…Owing to the wide variety of mulberry species, the composition and efficacy of mulberry leaf flavonoids (MLFs) may vary across varieties. Thus, it is necessary to further study its components and pharmacological properties [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

Anti-Inflammatory Activity of Mulberry Leaf Flavonoids In Vitro and In Vivo

Lin

Gan

Huang

et al. 2022

IJMS

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Mulberry (Morus alba L.) is a flowering tree traditionally used in Chinese herbal medicine. Mulberry leaf flavonoids (MLFs) have been reported to exert important anti-inflammatory and antioxidant properties. The purpose of this study was to select the MLF with the best anti-inflammatory and antioxidative activities from MLFs eluted by different ethanol concentrations (30%, 50%, and 75%) and explore its pharmacological properties. Three types of MLFs inhibited the production of nitric oxide (NO), prostaglandin E2 (PGE2), inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and inflammatory cytokines in lipopolysaccharide (LPS)-induced RAW 264.7 cells. All MLFs boosted the antioxidative capacity by decreasing the reactive oxygen species (ROS) production and the scavenging of 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radicals and improving the metal ion chelating activity and reducing power. The results revealed that the MLFs eluted by 30% ethanol exhibited the best anti-inflammatory and antioxidative activities. A nontargeted metabolomic analysis was used to analyze 24 types of differential flavonoids between the MLFs. Quercetin, kaempferol, and their derivatives in 30%MLF were more abundant than the other two MLFs. Furthermore, we evaluated the pharmacological activities of 30%MLF in dextran sodium sulfate (DSS)-induced ulcerative colitis (UC) mice. The 30%MLF could alleviate the clinical symptoms, reduce the secretion of inflammatory cytokines, and inhibit the activation of the inflammatory pathway in DSS-induced colitis mice. This study will provide valuable information for the development of MLFs eluted by 30% ethanol as a functional food.

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Phytochemistry, bioactivities and future prospects of mulberry leaves: A review

Cited by 97 publications

References 100 publications

Effects of modified atmosphere packaging on the postharvest quality of mulberry leaf vegetable

Effects of modified atmosphere packaging on the postharvest quality of mulberry leaf vegetable

Synthesis and Applications of Green Synthesized TiO₂ Nanoparticles for Photocatalytic Dye Degradation and Antibacterial Activity

Anti-Inflammatory Activity of Mulberry Leaf Flavonoids In Vitro and In Vivo

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Phytochemistry, bioactivities and future prospects of mulberry leaves: A review

Cited by 97 publications

References 100 publications

Effects of modified atmosphere packaging on the postharvest quality of mulberry leaf vegetable

Effects of modified atmosphere packaging on the postharvest quality of mulberry leaf vegetable

Synthesis and Applications of Green Synthesized TiO2 Nanoparticles for Photocatalytic Dye Degradation and Antibacterial Activity

Anti-Inflammatory Activity of Mulberry Leaf Flavonoids In Vitro and In Vivo

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Product

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Synthesis and Applications of Green Synthesized TiO₂ Nanoparticles for Photocatalytic Dye Degradation and Antibacterial Activity