“…In order to maintain the effectiveness of antibiotic, the reduction of resistance is thought to be more valuable than to select newer and stronger antibiotics. As well as the numerous synthetic compounds, many natural products were found to possess antibiotic activities (Yashphe, et al, 1979;Sharma, et aL, 1980;Janssen, et al, 1984;Onawunmi, et al, 1984;Paster, et aL, 1990;Garg, et al, 1992;Soliman, et aL, 1994;Marotti, et al, 1994;Gundidza, et aL, 1994;Shin, 1996).…”