Phytoconstituents of Leaves and Roots Ethanolic Extract of Talinum paniculatum and Their Biological Activities

Abstract

Javanese ginseng (Talinum paniculatum) is known to the people of Indonesia to have properties in medicine and food. People's culture generally uses leaves and roots that, until now, constituent information has yet to bereported. Therefore, variations of phytoconstituents in the leaves and roots of T. paniculatum were investigated using Gas Chromatography-Mass Spectrometry (GC-MS). The roots of T. paniculatum contain 17 active compounds dominated by N,N'-Dibutyl-N,N'-dimethylurea. The leaf has only 16 active compounds, but Python compounds from the diterpenoids class dominate it. In general, T. paniculatum contains a variety of steroid class compounds, namely Stigmasterol; Stigmast-5-en-3-ol; and 9,19-Cycloergost-24(28)-en-3-ol, 4,14-dimethyl-, acetate, (3,β., 4.α., 5.α.) - in the leaves, and stigmasterol and .γ.Sitosterol in the root. Python is known to have high efficacy as an antimicrobial, antifungal, antibacterial, antiparasitic, antimutagenic, and antioxidant. At the same time, steroid compounds are anti-cancer, antioxidant, anti-tumor, antidiabetic, and anti-inflammatory agents. The results of identifying compounds in T. paniculatum can be used as a reference in optimizing the use of T. paniculatumin the future.