Phytoperspective of Moringa oleifera for oral health care: An innovative ethnomedicinal approach

Abstract

The present era accentuate the use of alternative medicines as drugs extracted from several plant parts. These herbal medicines otherwise called ethnomedicines are now the source of many imperative drugs in this contemporary world. Furthermore with ever rising oral problems by luxurious lifestyle in this modern society, there is a soaring need for use of potent medicinal plants like horse radish (Moringa oleifera Lam.) against various oral ailments. Therefore, use of herbal medicines in reducing the adverse effects of various conventional allopathic medicines and harmful side effects of conventional antibiotics has emerged as an evolved technique in pharmaceutical science. The present review emphasizes the antipathogenic potentiality of M. oleifera along with their known therapeutic properties through biologically active compounds (phytoconstituents) and ethnomedicinal uses. Various ethno‐pharmacological studies of the plant parts with their nutritional value and multifarious medicinal uses including oral health care are being quoted in present review. This review will foster future research on phytoconstituent analysis, bioefficacy assessment for oral micro flora and ethno‐pharmaceutical importance of M. oleifera in the field of medical science with special reference to dentistry. Consequently, this innovative ethnomedicinal approach for oral health care may supplement the modern medicine through its potent phytoconstituents.

Molecular docking of bioactive compounds derived from Moringa oleifera with p53 protein in the apoptosis pathway of oral squamous cell carcinoma

“…Eight bioactive compounds from M. oleifera were selected which possess anti-cancer property based on literature review [4,20,21]. The 3D structures of those compounds were downloaded with help of PubChem database in SDF file format, which then was converted to .pdb file format using the BIOVIA Discovery Studio 2021 Client [18] (Fig.…”

Evaluation of Anti-Inflammatory Effect of Moringa oleifera Lam. and Cyanthillium cinereum (Less) H. Rob. Lozenges in Volunteer Smokers

“…This was supported by a previous report from Egypt where MO leaf extract significantly decreased periodontal inflammation by reducing leptin and IL-6 serum levels in a male albino rat periodontal model [ 59 ], while MO leaf extract also reduced production of TNF-α and IL-1β in the gum tissue in a male Wistar rat periodontal model ( p ≤ 0.001) [ 60 ]. Moreover, a variety of products from MO leaf are available for cleaning the teeth and gums, and treatment of oral ailments such as MO tooth powder, MO solution, mouthwash, and toothpaste [ 61 ]. However, this present study, the percentage decrease of oral inflammation in the placebo group was possibly caused from the activity of peppermint essential oil and menthol essential oil, which displayed antioxidant and anti-inflammation activities [ 62 , 63 ].…”

Moringa oleifera Seed at the Interface of Food and Medicine: Effect of Extracts on Some Reproductive Parameters, Hepatic and Renal Histology

“…However, until now, there are currently no reported scientific findings on the potential effects of MOSE on fertility and pregnancy outcome. Yet the application of lipid-rich Moringa whole seed as well as the aqueous extracts of MOSE (containing suspended lipids) as an anti-infective and restorative nutraceutical ( Xiong et al, 2020 ; Mohanty et al, 2021 ; Oyeleye et al, 2021 ; Reyes-Becerril et al, 2021 ; Santos et al, 2021 ; Xiong et al, 2021 ), as food additive ( Milla et al, 2021 ; Okereke et al, 2021 ; Oyeleye et al, 2021 ) as well as for polluted water treatment in deprived rural settings ( Lea, 2010 ; Palada, 2019 ; Aboagye et al, 2021 ; Ueda Yamaguchi et al, 2021 ) has continued to gain momentum across different regions of the world without any attention to its potential toxicities. Here, the effects of the lipid-containing MOSE aqueous-methanol extracts on fertility and pregnancy outcome have been elaborately investigated in vivo using rodents for their potential effects on reproductive parameters, ovary, uterus, renal and hepatic histology.…”