Phytotoxic and antifungal metabolites from Curvularia sp. FH01 isolated from the gut of Atractomorpha sinensis

Zhang, Yinglao; Kong, Lichun; Jiang, Donghua; Yin, Caiping; Cai, Qingsheng; Chen, Qiong; Zheng, Jiang-yan

doi:10.1016/j.biortech.2010.10.028

Cited by 32 publications

(29 citation statements)

References 15 publications

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“…Colonies of QTYC-1 on malt-extract agar (MEA) grew quickly at 28 °C, covering the whole plate (9 cm in diameter) in 10 days. The morphological features of the strain QTYC-1 were similar to those of Curvularia sp [ 2 ], which produced four-celled ellipsoidal conidia. Phylogenetic taxonomy with the sequence alignment of ITS (Internal Transcribed Spacer) rDNA of the fungus was achieved with MEGA 5.0 software ( ).…”

Section: Resultsmentioning

confidence: 75%

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Phytotoxic and Antifungal Metabolites from Curvularia crepinii QTYC-1 Isolated from the Gut of Pantala flavescens

et al. 2018

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Four metabolites (1–4), including a new macrolide, O-demethylated-zeaenol (2), and three known compounds, zeaenol (1), adenosine (3), and ergosta-5,7,22-trien-3b-ol (4) were isolated and purified from Curvularia crepinii QTYC-1, a fungus residing in the gut of Pantala flavescens. The structures of isolated compounds were identified on the basis of extensive spectroscopic analysis and by comparison of the corresponding data with those reported in the literature previously. The new compound 2 showed good phytotoxic activity against Echinochloa crusgalli with an IC50 value of less than 5 µg/mL, which was comparable to that of positive 2,4-dichlorophenoxyacetic acid (2,4-D). Compound 1 exhibited moderate herbicidal activity against E. crusgalli with an IC50 value of 28.8 μg/mL. Furthermore, the new metabolite 2 was found to possess moderate antifungal activity against Valsa mali at the concentration of 100 µg/mL, with the inhibition rate of 50%. These results suggest that the new macrolide 2 and the known compound 1 have potential to be used as biocontrol agents in agriculture.

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Section: Resultsmentioning

confidence: 75%

“…Both weeds and plant fungal diseases have always been thought as big agricultural and environmental problems [ 1 , 2 , 3 ]. Organic synthetic herbicides and fungicides are widely used to control these issues.…”

Section: Introductionmentioning

confidence: 99%

Phytotoxic and Antifungal Metabolites from Curvularia crepinii QTYC-1 Isolated from the Gut of Pantala flavescens

et al. 2018

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“…Antifungal assays were performed as described (Zhang et al 2011(Zhang et al , 2013) with a little modification. Purified compound 1 was dissolved in a volume of aqueous solution (composed of 1% DMSO and 4% Tween-80) to obtain the final concentration of 100 µg/mL.…”

Section: Antifungal Activity Of the Metabolitementioning

confidence: 99%

Diversity and antagonistic potential of Actinobacteria from the fungus-growing termite Odontotermes formosanus

Yin

Jin

et al. 2019

3 Biotech

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43 Actinobacteria were isolated from the nest of Odontotermes formosanus. A phylogenetic analysis of 23 Actinobacteria isolates with different morphotypes showed that they did not form a monophyletic group. Antifungal bioassays exhibited that many strains inhibit both the termite cultivar Termitomyces and the competitor Xylaria. However, Actinobacteria inhibited the competitor Xylaria more severely than the termite cultural fungus Termitomyces. Furthermore, two Actinobacteria (Streptomyces sp. T33 and S. bellus T37) had a selective antifungal effect on Xylaria, with the inhibition zone of 25.5 and 8.9 mm, respectively. An actinomycin D was isolated from the strain T33 and had potent antifungal activity against Xylaria with IC 50 value of less than 3.1 µg/mL. In addition, further bioassays showed that actinomycin D possessed potent antifungal activities against Magnaporthe grisea (IC 50 = 0.9 µg/mL), Fusarium oxysporum f. sp. cucumerinum (IC 50 = 2.2 µg/mL), Valsa mali (IC 50 = 1.7 µg/mL), Rhizoctonia solani (IC 50 = 10.3 µg/mL), Dothiorella gregaria (IC 50 = 12.5 µg/mL) and F. oxysporum f. sp. mornordicae (IC 50 = 14.3 µg/mL), which were comparable to those of referenced cycloheximide. The findings of the present study suggest that the termite-associated Actinobacteria have a potential to be used as microbial fungicide.

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“…[6] Daldinia eschscholzii, isolated from the gut of the mantis species Tenodera aridifolia, was reported to simultaneously generate four novel skeletons and seven structurally unique metabolites that have the potential to become immune inhibitors. [7,8] [11]…”

Section: Introductionmentioning

confidence: 99%

Isolation of Bioactive Metabolites Producing Fungal Strains From Milk Products and Milk Industries of Raipur District

Saraf¹

2017

WJPPS

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For the discovery of new therapeutic candidates, natural products continue to play an important role. Over the past 3 decades, natural products or their derivatives have been reported to produce about 60% of new anticancer agents and almost 75% of all new antimicrobial molecules which account for antibacterial, antifungal, antiprotozoal and antiviral molecules. More than a hundred natural products and natural product-derived substances were being evaluated in clinical trials or were being registered at the end of 2015. Bioactive or secondary metabolites have been isolated from a variety of terrestrial and marine organisms, including plants, marine invertebrates and microorganisms. Microorganisms (traditionally bacteria and filamentous fungi, but the recent advances include cyanobacteria, microalgae and myxobacteria) are one of the most prevalent sources for the production of bioactive molecules. Exploitation of their specialized (or secondary) metabolism has guaranteed for decades the discovery of novel antibiotics and other compounds with unprecedented chemical characteristics and biological properties not existing in screening. The current study is based on isolation and exploitation of the secondary metabolism of such fungal strains that prove potential source of such bioactive molecules and also for pharmaceutical drug discovery programs.

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Phytotoxic and antifungal metabolites from Curvularia sp. FH01 isolated from the gut of Atractomorpha sinensis

Cited by 32 publications

References 15 publications

Phytotoxic and Antifungal Metabolites from Curvularia crepinii QTYC-1 Isolated from the Gut of Pantala flavescens

Phytotoxic and Antifungal Metabolites from Curvularia crepinii QTYC-1 Isolated from the Gut of Pantala flavescens

Diversity and antagonistic potential of Actinobacteria from the fungus-growing termite Odontotermes formosanus

Isolation of Bioactive Metabolites Producing Fungal Strains From Milk Products and Milk Industries of Raipur District

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