Mental health concerns in eating disorders stem from the high suicide rate in the adolescent population. People at risk of developing eating disorders are more likely to have associated psychological problems, such as anxiety, depression and insomnia, and the risk of suicide is significantly increased. The suicidal behavior of the conditions is not well understood, and much uncertainty remains regarding pathophysiology, prevention, and treatment. Consideration of issues that need to be resolved, the prospects for the development of new methods of treatment in solving the problems of the problem seems to be very relevant. The aim of the review is to summarize the risk factors for suicidal tendencies associated with eating disorders and the protective mechanisms of suicide prevention. Results. A review of domestic and foreign literature describing the risk factors for suicidality was carried out. Attention is drawn to the interpersonal and psychological factors of suicide, in particular to the perceived burdensomeness of the disorder, low interoceptive awareness. The role of the family and genetic risks, comorbid and gender features of the development of the disease were revealed. A significant proportion of adolescents with eating disorders are characterized by the completion of suicidal intentions. The development of preventive programs aimed at developing and increasing confidence in one's body helps to reduce the risk of suicidal thoughts in young people who are dissatisfied with their physique. It is recommended to pay attention not only to nutritional support (enteral or parenteral), but also to the prevention of a high risk of suicidal intentions. The analysis made it possible to identify new directions for suicide prevention against the background of basic therapy and correction of eating disorders. Overcoming low mental literacy about getting help, identifying and managing people with manifestations of depression, combined with eating disorders, will reduce the risk of suicide. Prevention of brain-derived neurotrophic factor dysfunction, development and inclusion of methods to increase its concentration can play a significant role in preventing both the pathophysiology of eating behavior and suicidal intentions. Further research is needed to identify comorbid conditions and predictors of suicide in patients with anorexia nervosa, bulimia nervosa, and other eating disorders.