Picosecond alexandrite laser is superior to Q-switched Nd:YAG laser in treatment of minocycline-induced hyperpigmentation: A case study and review of the literature

Barrett, Tom; Zwaan, Sally de

doi:10.1080/14764172.2017.1418514

Cited by 18 publications

(16 citation statements)

References 16 publications

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“…Although these reports cast an optimistic outlook on the expanded use of picosecond lasers, further evidence is required in order to draw reliable conclusions. That being said, it is worthwhile noting that some traditionally difficult conditions to treat, such as minocycline-induced hyperpigmentation and chronic venous stasis hyperpigmentation have shown promising response and the use of picosecond laser in these settings should be considered an alternative treatment option when other modalities have proven unsatisfactory [30][31][32][33][34][35][36][37][38][39][41][42][43][44][45]94].…”

Section: Other Non-melasma Pigmented Conditionsmentioning

confidence: 99%

A Systematic Review of Picosecond Laser in Dermatology: Evidence and Recommendations

et al. 2020

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Background and Objectives The use of picosecond laser in dermatology was originally focused on optimizing the removal of unwanted tattoos. Subsequent advances in this technology have broadened its clinical indications to include treatment of benign pigmented lesions, photodamage, melasma, and scar revision. In this systematic review, evidence‐based recommendations are developed for the use of picosecond laser in dermatology. Study Design/Materials and Methods A comprehensive search of the English language literature was performed up to and including November 2019. Relevant citations were individually evaluated, synthesized, and categorized based on the Level of Evidence. With the addition of the authors’ combined clinical experience, clinical recommendations were developed. Results After application of inclusion and exclusion criteria, a total of 77 unique studies were evaluated. Treatment of benign pigmented lesions was associated with level I–IV evidence; rejuvenation was associated with level II evidence; melasma was associated with level II evidence; scar revision was associated with level II–III evidence; tattoo removal was associated with level I evidence. Conclusion Picosecond laser is a safe and effective treatment modality for an increasing range of dermatologic indications. Further development of this technology is warranted. Lasers Surg. Med. © 2020 Wiley Periodicals, Inc.

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Section: Other Non-melasma Pigmented Conditionsmentioning

confidence: 99%

A Systematic Review of Picosecond Laser in Dermatology: Evidence and Recommendations

et al. 2020

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“…After three treatments with a 755-nm alexandrite picosecond laser and a 2.5-year follow-up, pigmentation completely disappeared, which was verified by dermoscopy. Barrett et al 14 reported the case of an 81-year-old white woman with PIH caused by oral minocycline for rosacea. Five treatments with a 1064-nm nanosecond laser and 532nm Q-switched laser produced poor results, but four subsequent treatments with a 755-nm alexandrite picosecond laser produced complete disappearance of the pigmentation.…”

Section: Discussionmentioning

confidence: 99%

755-nm Alexandrite Picosecond Laser with a Diffractive Lens Array or Zoom Handpiece for Post-Inflammatory Hyperpigmentation: Two Case Reports with a Three-Year Follow-Up

Ren

Bao

Qian

et al. 2021

CCID

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Objective: Post-inflammatory hyperpigmentation (PIH) is a reactive hypermelanosis of various skin types, which occurs as a sequela of cutaneous inflammation or injury. Despite generally a self-limited and temporary condition, PIH is still a frustrating problem that can have significant psychosocial effects on patients, especially those with darker skin types. Laser therapy is one of the effective treatments for PIH, and various wavelength lasers and light devices have been utilized in PIH therapy. Nonetheless, data on the long-term efficacy of the 755-nm alexandrite picosecond laser are limited. Methods: This study analyzed two cases of PIH treated with a combination of a 755-nm alexandrite picosecond laser and a diffractive lens array or zoom handpiece. Efficacy of the treatment was determined by the images of skin lesions under a fixed light source before and after each treatment, which were independently reviewed by two plastic-surgery specialists blinded to the clinical data. Improvement was classified as complete (>75%), significant (50-75%), mild (25-50%), and inefficient (<25% or no obvious change). Skin imaging analysis was carried out using the VISIA system (Canfield, USA), and dermoscopy was performed at the same time. Results: After two to three courses of treatment, all cases showed significant or complete improvement, and no recurrence was observed during the three years of follow-up. Conclusion: A 755-nm alexandrite picosecond laser in combination with a diffractive lens array or zoom handpiece had significant and long-term efficacy for the treatment of PIH caused by trauma. However, attention should be paid to the problem of transient deepening of pigmentation during treatment.

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“…In this meta‐analysis from Asian patients treated with a PS laser, the proportions of patients achieving excellent outcomes were higher for nevus of Ota and solar lentigines, consistent with the literature. On the other hand, the treatment of other nonmelasma pigmentary lesions with PS laser was satisfactory 44‐58 . Based on a systematic review, the level of evidence for the use of the PS laser for other pigmentary lesions was 4, 15 highlighting the need for high‐quality research on the subject.…”

Section: Discussionmentioning

confidence: 99%

Treatment of pigmentary disorders using picosecond laser in Asian patients: A meta‐analysis and systematic review

Dong

Wang

Yuan

et al. 2021

Dermatologic Therapy

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There were many studies evaluating the effect of picosecond (PS) lasers, but no meta‐analysis examined the effects of PS laser in the treatment of pigmentary disorders in Asians. The aim of this article was to review the before‐after effect of PS laser in Asians for the treatment of pigmentary disorders. PubMed, Embase, and Cochrane library were searched for articles published up to May 2020. The evaluations were summarized into a 4‐point scale that ranged from <25% (poor), 25%‐50% (fair), 50%‐75% (good), and 75%‐100% (excellent). Effect sizes (ESs) were calculated according to laser wavelengths and lesion types. There were two randomized controlled trials, three single‐arm trials, and three case series, with 200 patients. At 3 months after treatment, of all included patients, 3% (95%CI: 1%‐6%) were evaluated as poor or worse, 9% (95%CI: 2%‐21%) as fair, 29% (95%CI: 12%‐50%) as good, and 56% (95%CI: 28%‐83%) as excellent. The 532 and 1064, and 755 nm PS lasers had similar ESs across all four response groups. This meta‐analysis suggested that 56% of Asian patients who underwent PS laser for the treatment of pigmentary disorders were evaluated as “excellent” about the pigment clearance by a dermatologist at least 3 months after treatment.

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Picosecond alexandrite laser is superior to Q-switched Nd:YAG laser in treatment of minocycline-induced hyperpigmentation: A case study and review of the literature

Cited by 18 publications

References 16 publications

A Systematic Review of Picosecond Laser in Dermatology: Evidence and Recommendations

A Systematic Review of Picosecond Laser in Dermatology: Evidence and Recommendations

755-nm Alexandrite Picosecond Laser with a Diffractive Lens Array or Zoom Handpiece for Post-Inflammatory Hyperpigmentation: Two Case Reports with a Three-Year Follow-Up

Treatment of pigmentary disorders using picosecond laser in Asian patients: A meta‐analysis and systematic review

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