Pierre-Marie-Bamberger syndrome – A paraneoplastic syndrome of solitary fibrous tumour of the pleura

Abstract

The authors report a case of a 75-year-old woman who presented to the Emergency Department with dyspnoea, productive cough, vomiting and unquantified weight loss. She denied fever, night sweats or other symptoms. She had a past history of dementia, dyslipidaemia and right total hip replacement. No relevant family history was known. On physical examination, the patient was fully awake, relatively mobile and disoriented to place and time. Her vital signs were within normal limits with an oxygen saturation of 94% on room air. Lung examination revealed absence of breath sounds over the right hemithorax with increased dullness to percussion. Bilateral pitting oedema extending to the joints was seen in the lower extremities. She complained of pain while palpating both femurs. Digital clubbing was also notable (Figure 1A). Laboratory findings were as follows: haemoglobin 13.7 g/dL (normal, 12-15), mean corpuscular volume 82.6 fL (normal, 83-101), leucocytes 13.7x10 9 /L (normal, 4-10), platelets 310x10 9 /L (normal, 150-400), lactate dehydrogenase 442 U/L (normal, 125-220), C-reactive protein 4.97