Piezocatalytic strategy facilitates diabetic bone regeneration through high-performance anti-oxidative recycling

Sun, Jiwei; Zhang, Junyuan; Yang, Lina; Zhang, Cencen; Wang, Yifan; Lei, Haoqi; Wo, Keqi; Fan, Wenjie; Zhao, Baoying; Wang, Jinyu; Shi, Yunsong; Luo, Zhiqiang; Su, Bin; Song, Jinlin; Chu, Yingying; Chen, Lili

doi:10.1016/j.cej.2023.147931

“…Natural biophysical microenvironment comprised of temperature, light, topographic structure, electrical and mechanical cues, play crucial roles in homeostasis of normal tissue and regeneration of defects and wounds [ 5 – 8 ]. In particular, mechanical and electrical cues are of great importance and have been the focus of research during recent years [ 9 , 10 ]. Based on this theory, novel therapeutic strategies in tissue engineering have been developed to mimic extracellular characteristics for improved tissue regeneration [ 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Remote coupling of electrical and mechanical cues by diurnal photothermal irradiation synergistically promotes bone regeneration

Lei,

Sun,

Dai

et al. 2024

J Nanobiotechnol

0

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Recapitulating the natural extracellular physical microenvironment has emerged as a promising method for tissue regeneration, as multiple physical interventions, including ultrasound, thermal and electrical therapy, have shown great potential. However, simultaneous coupling of multiple physical cues to highly bio-mimick natural characteristics for improved tissue regeneration still remains formidable. Coupling of intrinsic electrical and mechanical cues has been regarded as an effective way to modulate tissue repair. Nevertheless, precise and convenient manipulation on coupling of mechano-electrical signals within extracellular environment to facilitate tissue regeneration remains challengeable. Herein, a photothermal-sensitive piezoelectric membrane was designed for simultaneous integration of electrical and mechanical signals in response to NIR irradiation. The high-performance mechano-electrical coupling under NIR exposure synergistically triggered the promotion of osteogenic differentiation of stem cells and enhances bone defect regeneration by increasing cellular mechanical sensing, attachment, spreading and cytoskeleton remodeling. This study highlights the coupling of mechanical signals and electrical cues for modulation of osteogenesis, and sheds light on alternative bone tissue engineering therapies with multiple integrated physical cues for tissue repair. Graphical Abstract

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Polydopamine‐Mediated Contact‐Electro‐Catalysis for Efficient Partial Oxidation of Methane

Jia,

Wang,

Zhang

et al. 2024

Angewandte Chemie

0

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The direct conversion and efficient utilization of methane pose a critical scientific challenge. Indirect activation via reactive oxygen species (ROS) offers a high probability of contact with methane and conversion efficiency under mild conditions. However, reported product yields are suboptimal due to challenges in activating oxygen and facilitating mass transfer in suspension systems. We propose the use of contact‐electro‐catalysis (CEC), employing polydopamine (PDA) as a catalyst that undergoes electron transfer with oxygen under ultrasound, generating ROS that drives the partial oxidation of methane (POM). Corresponding experimental results indicate that CH3OH and most HCHO are produced directly from CH4. Furthermore, through in situ characterizations, we have shown that light pretreatment of the catalysts in an oxygenated atmosphere facilitates the forming of more C=O functional groups with strong electron‐withdrawing properties, thereby significantly enhancing overall product yields, particularly for CH3OH. Within two hours, product yields reach 1.5 mmol·gcat−1 for HCHO and 0.9 mmol·gcat−1 for CH3OH. This work introduces a novel approach for efficient POM, while highlighting the distinctive catalytic properties of PDA.

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Polydopamine‐Mediated Contact‐Electro‐Catalysis for Efficient Partial Oxidation of Methane

Jia,

Wang,

Zhang

et al. 2024

Angew Chem Int Ed

0

View full text Add to dashboard Cite

The direct conversion and efficient utilization of methane pose a critical scientific challenge. Indirect activation via reactive oxygen species (ROS) offers a high probability of contact with methane and conversion efficiency under mild conditions. However, reported product yields are suboptimal due to challenges in activating oxygen and facilitating mass transfer in suspension systems. We propose the use of contact‐electro‐catalysis (CEC), employing polydopamine (PDA) as a catalyst that undergoes electron transfer with oxygen under ultrasound, generating ROS that drives the partial oxidation of methane (POM). Corresponding experimental results indicate that CH3OH and most HCHO are produced directly from CH4. Furthermore, through in situ characterizations, we have shown that light pretreatment of the catalysts in an oxygenated atmosphere facilitates the forming of more C=O functional groups with strong electron‐withdrawing properties, thereby significantly enhancing overall product yields, particularly for CH3OH. Within two hours, product yields reach 1.5 mmol·gcat−1 for HCHO and 0.9 mmol·gcat−1 for CH3OH. This work introduces a novel approach for efficient POM, while highlighting the distinctive catalytic properties of PDA.

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Piezocatalytic strategy facilitates diabetic bone regeneration through high-performance anti-oxidative recycling

Cited by 6 publications

References 26 publications

Remote coupling of electrical and mechanical cues by diurnal photothermal irradiation synergistically promotes bone regeneration

Remote coupling of electrical and mechanical cues by diurnal photothermal irradiation synergistically promotes bone regeneration

Polydopamine‐Mediated Contact‐Electro‐Catalysis for Efficient Partial Oxidation of Methane

Polydopamine‐Mediated Contact‐Electro‐Catalysis for Efficient Partial Oxidation of Methane

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