Piezoelectric Peptide and Metabolite Materials

Yuan, Hui; Han, Peipei; Tao, Kai; Liu, Shuhai; Gazit, Ehud; Yang, Rusen

doi:10.34133/2019/9025939

Cited by 61 publications

(48 citation statements)

References 129 publications

(192 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The di‐phenylalanine (FF), the dipeptides of two phenylalanine (F), is one of the most notable piezoelectric biomolecules 77–88. The FF dipeptide can self‐assemble into well‐ordered nano‐microtubes by a hydrogen bonding and π–π stacking to form a non‐centrosymmetric hexagonal crystal structure (C 6 ) that can exhibit piezoelectricity ( Figure a) 89–94. In 2010 by Kholkin et al, FF nano‐microtubes were synthesized by a solution process and examined by piezoresponse force microscopy (PFM) technique for the first time 83.…”

Section: Piezoelectricity Of Peptidementioning

confidence: 99%

Biomolecular Piezoelectric Materials: From Amino Acids to Living Tissues

et al. 2020

View full text Add to dashboard Cite

Biomolecular piezoelectric materials are considered a strong candidate material for biomedical applications due to their robust piezoelectricity, biocompatibility, and low dielectric property. The electric field has been found to affect tissue development and regeneration, and the piezoelectric properties of biological materials in the human body are known to provide electric fields by pressure. Therefore, great attention has been paid to the understanding of piezoelectricity in biological tissues and its building blocks. The aim herein is to describe the principle of piezoelectricity in biological materials from the very basic building blocks (i.e., amino acids, peptides, proteins, etc.) to highly organized tissues (i.e., bones, skin, etc.). Research progress on the piezoelectricity within various biological materials is summarized, including amino acids, peptides, proteins, and tissues. The mechanisms and origin of piezoelectricity within various biological materials are also covered.

show abstract

Section: Piezoelectricity Of Peptidementioning

confidence: 99%

Biomolecular Piezoelectric Materials: From Amino Acids to Living Tissues

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Ferroelectricity and piezoelectricity have been found in FF nanostructures. [ 37 ] The inherent mechanical properties and ferroelectric behaviors of the aligned peptides enabled the development of versatile device applications [ 38,39 ] including nanogenerators, [ 12 ] energy‐storage devices, [ 28 ] and sensors. [ 33 ] On the other hand, for our FF‐HNs, it should be noted that the FF nanostructures are randomly oriented in each microfiber (Figure 1c).…”

Section: Resultsmentioning

confidence: 99%

Large‐Scale Assembly of Peptide‐Based Hierarchical Nanostructures and Their Antiferroelectric Properties

Lee

Kim

Duong

et al. 2020

Small

View full text Add to dashboard Cite

organized structures enable the expression of completely different physical properties, which are absent in the basic material, and endow many biological materials with remarkable mechanical strength, [4] flexibility, [5] super-hydrophobicity, [6] and optical properties, [7] such as structural color. Therefore, many researchers have made great efforts to develop novel materials with unique physical properties and improved performance over conventional materials by mimicking these natural hierarchical structures. Although various biomaterials, such as DNA, [8] bacteriophages, [9] proteins, [10] carbohydrates, [11] and peptides, [12] are being researched and developed for this purpose, self-assembled peptide nanostructures [13] are most actively studied among them owing to their versatile properties. Diphenylalanine (FF) molecules, especially those derived from the dipeptide motif (-F19-F20-), which is a major contributing factor in amyloid fibril formation that causes Alzheimer's disease, are widely used to form peptide hierarchical nanostructures through a self-assembly process that induces the aggregation of FF molecules in water. [14] This molecular self-assembly approach enables us to build diverse peptide nanostructures with functional physical and chemical properties, including piezoelectricity, [15] ferroelectricity, [16] and photoluminescence, [17] as well as robust An effective strategy is developed to create peptide-based hierarchical nanostructures through the meniscus-driven self-assembly in a large area and fabricate antiferroelectric devices based on these nanostructures for the first time. The diphenylalanine hierarchical nanostructures (FF-HNs) are self-assembled by vertically pulling a substrate from a diphenylalanine (FF) solution dissolved in a miscible solvent under precisely controlled conditions. Owing to the unique structural properties of FF nanostructures, including high crystallinity and α-helix structures, FF-HNs possess a net electrical dipole moment, which can be switched in an external electric field. The mass production of antiferroelectric devices based on FF-HNs can be successfully achieved by means of this biomimetic assembly technique. The devices show an evident antiferroelectric to ferroelectric transition under dark conditions, while the ferroelectricity is found to be tunable by light. Notably, it is discovered that the modulation of antiferroelectric behaviors of FF-HNs under glutaraldehyde exposure is due to the FF molecules that are transformed into cyclophenylalanine by glutaraldehyde. This work provides a stepping stone toward the mass production of self-assembled hierarchical nanostructures based on biomolecules as well as the mass fabrication of electronic devices based on biomolecular nanostructures for practical applications.

show abstract

“…It is widely used in transducers to converse the mechanical energy into electrical energy. Since the piezoelectric effect was discovered by the Curie brothers in 1880, a variety of piezoelectric materials have been invented, which can be separated into the following two categories: (1) inorganic materials, such as ZnO [44], lead zirconium titanate (PZT) [45], barium titanate (BT), modified lead zirconate titanate [46], lead metaniobate, lead niobate barium lithium (PBLN), and modified lead titanate (PT) [47,48]; (2) organic materials, such as polyvinyl chloride (PVC), polyvinylidene fluoride (PVDF) [49] and its derives [50], and some other materials [51][52][53]. All the materials have been studied in fabricating 3 Research PENGs, as shown in Table 1.…”

Section: Materials and Devicesmentioning

confidence: 99%

Nanogenerator-Based Self-Powered Sensors for Wearable and Implantable Electronics

et al. 2020

View full text Add to dashboard Cite

Wearable and implantable electronics (WIEs) are more and more important and attractive to the public, and they have had positive influences on all aspects of our lives. As a bridge between wearable electronics and their surrounding environment and users, sensors are core components of WIEs and determine the implementation of their many functions. Although the existing sensor technology has evolved to a very advanced level with the rapid progress of advanced materials and nanotechnology, most of them still need external power supply, like batteries, which could cause problems that are difficult to track, recycle, and miniaturize, as well as possible environmental pollution and health hazards. In the past decades, based upon piezoelectric, pyroelectric, and triboelectric effect, various kinds of nanogenerators (NGs) were proposed which are capable of responding to a variety of mechanical movements, such as breeze, body drive, muscle stretch, sound/ultrasound, noise, mechanical vibration, and blood flow, and they had been widely used as self-powered sensors and micro-nanoenergy and blue energy harvesters. This review focuses on the applications of self-powered generators as implantable and wearable sensors in health monitoring, biosensor, human-computer interaction, and other fields. The existing problems and future prospects are also discussed.

show abstract

Piezoelectric Peptide and Metabolite Materials

Cited by 61 publications

References 129 publications

Biomolecular Piezoelectric Materials: From Amino Acids to Living Tissues

Biomolecular Piezoelectric Materials: From Amino Acids to Living Tissues

Large‐Scale Assembly of Peptide‐Based Hierarchical Nanostructures and Their Antiferroelectric Properties

Nanogenerator-Based Self-Powered Sensors for Wearable and Implantable Electronics

Contact Info

Product

Resources

About