Pigment Cells in Eyes of People with Vitiligo

Ej, Moynahan

doi:10.1056/nejm197704072961429

Cited by 4 publications

(3 citation statements)

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“…AlGhamdi, & E. Osman (2016) [ 21 ] Mostafa W.Z., et al (2015) [ 18 ] Gass, J.D. (1981) [ 19 ] Iris Atrophy & Pigmentary Abnormalities Several studies reported findings of iris atrophy and/or pigmentary abnormalities [ 6 , 7 , 16 , 20 , 22 – 25 ]. While findings of iris atrophy were overall higher in vitiligo patients compared to healthy controls, the prevalence was variable, ranging from 0%-25.5% [ 6 , 23 , 24 ].…”

Section: Introductionmentioning

confidence: 99%

“…The iritis was associated with heterochromia [ 6 ]. Another study reported iritis in 12.5% of vitiligo patients [ 25 ]. There does not appear to be a significant difference in iris color between the vitiligo and control groups [ 7 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

“…& G. Olakunle (2005) [ 5 ] Karadag, R., et al (2016) [ 16 ] Cowan, C.L., Jr., et al(1986) [ 22 ] Fouad, Y.A., et al(2020) [ 20 ] Aydin, R., et al (2018) [ 29 ] El-Mofty, A.M. and A. El-Mofty (1979) [ 17 ] Khurrum, H., K.M. AlGhamdi, & E. Osman (2016) [ 21 ] Biswas, G., et al (2003) [ 23 ] Fleissig, E., et al (2018) [ 24 ] Wagoner, M.D., et al (1983) [ 30 ] Shoeibi, N., et al (2014) [ 33 ] Gopal, K.V.T., et al (2007) [ 7 ] Lerner, A.B., J.J Nordlund, & D.M Albert (1977) [ 25 ] Mehran, G., et al (2014) [ 34 ] Mostafa W.Z., et al (2015) [ 18 ] Perossini, M., et al (2010) [ 28 ] Shoeibi, N., et al (2016) [ 32 ] Gass, J.D. (1981) [ 19 ]…”

Section: Introductionmentioning

confidence: 99%

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Ocular manifestations of vitiligo: a systematic review

et al. 2023

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Vitiligo is a disorder characterized by loss of epidermal melanocytes, resulting in depigmented macules and patches. While the relationship between ocular pathology and vitiligo has been demonstrated in conditions such as Vogt-Koyanagi-Harada and Alezzandrini syndromes, the ocular associations of non-syndromic vitiligo are incompletely understood. We conducted a systematic review to comprehensively describe the structural and functional changes seen in the eyes of patients with vitiligo, to identify patients at heightened risk for ocular disease, and to provide an approach to management of ocular manifestations of vitiligo. Overall, the strongest link between vitiligo and ocular pathology seems to lie with dry eye disease and pigmentary abnormalities of various ocular structures, especially the retinal pigment epithelium. Normal-tension glaucoma may also be more prevalent in the vitiligo population. The available literature did not provide conclusive evidence for increased risk of cataracts or uveitis. Aside from the impact of symptomatic dry eye disease, it seems unlikely that there are significant functional consequences of these ocular manifestations such as impaired visual acuity or visual fields.

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