Pigmented adenomatoid odontogenic tumour

Abstract

A pigmented adenomatoid odontogenic tumour occurring in the mandible of a 12-year-old Japanese girl is reported. In addition to the characteristic histopathologic features, fine granules and coarse aggregates of melanin pigment were widely distributed in the spindle-shaped epithelial cells between duct-like structures, and dendritic cells containing melanin pigment were also distributed in tumour epithelium. The possible histogenesis of melanin pigment in the epithelial cells of the odontogenic lesions is discussed, although no firm conclusions could be drawn.

Adenomatoid odontogenic tumour: Tumour or a cyst, a histopathological support for the controversy

“…Further investigation is suggested if in an incisional biopsy, the presence of a thin cystic lining with lace like and nodular proliferation, juxtaepithelial hyalinization, calcification and lack of ghost cells are observed. Canines > maxillary incisor > premolars > molars Canine (n = 7), premolar/molar region (n = 5) [10,21,16,24,25], peripheral variant (n = 1) [27] Similar finding…”

Pattern of distribution of odontogenic tumours in sub-Saharan Africa

“…This can be gained by conducting comprehensive and large‐series epidemiological studies, in which aetiological factors implicated in their development can be identified from the population at risk. Review of the scientific literature shows that there are insufficient numbers of large‐series studies of OTs in sub‐Saharan Africa. A recent study of 3,641 cases of OT in sub‐Saharan Africa has been published.…”