1981
DOI: 10.2334/josnusd1959.23.1
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Pigmented squamous cell carcinoma of the oral mucosa - with special reference to the role of non-keratinocytes in tumors and tumorous conditions.

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Cited by 11 publications
(14 citation statements)
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“…In normal tissues, melanocytes act to protect keratinocytes from injuries (e.g. UV exposure) and to produce melanin pigments, representing about 3-5% of the cell population ( 9 ). Melanin accumulates in small granules called melanosomes, which can be present in varying numbers within melanocytes, Langerhans cells, macrophages and neoplastic squamous cells ( 11 ).…”
Section: Discussionmentioning
confidence: 99%
“…In normal tissues, melanocytes act to protect keratinocytes from injuries (e.g. UV exposure) and to produce melanin pigments, representing about 3-5% of the cell population ( 9 ). Melanin accumulates in small granules called melanosomes, which can be present in varying numbers within melanocytes, Langerhans cells, macrophages and neoplastic squamous cells ( 11 ).…”
Section: Discussionmentioning
confidence: 99%
“…Among malignant neoplasms of the oral mucosa, SCC is the most common histopathologic type and usually consists of a pure neoplastic keratinocytes without pigmentation (1). Although it has been stated that melanocyte colonization is a well‐recognized occurrence in a variety of tumors of the epidermis and the hair follicles, it is very rare in oral carcinomas (2, 3) We described here a case of pigmented SCC of the hard palate, and review the clinicopathological characteristics of the eight reported cases – including the present case of pigmented SCC in the oral mucosa (4–8). The mean age of patients was 71.8 years, with a range of 47–81 years.…”
Section: Commentsmentioning
confidence: 92%
“…This type of SCC may be difficult to distinguish from cutaneous melanoma. To our knowledge, only 13 cases of pigmented SCC have been reported in the English language literature, with most frequent development in the oral cavity or conjunctiva 1 –11 . However, no case of scrotal pigmented SCC has been reported.…”
mentioning
confidence: 99%