Pigmented Tumors of the Central Nervous System

A Rare Case of Primary Intracerebral Malignant Melanoma

“…Primary intracranial malignant melanomas are rare entities. These aggressive primary melanomas account for 0.07% of all brain tumors [ 1 - 2 ].…”

Histological Studies of Malignant Melanoma

“…18,21,23,24) 1) diffuse melanosis 2) absence of extracranial melanoma elsewhere 3) associated skin pigmentation However, the author gives no importance to the third of the above criteria, but the former two, particularly the second, seem to have an important value for the diagnosis of primary meningeal melanoma.…”

Primary Melanoma of the Leptomeninges

“…Forbes goes further and suggests that all cases in which there is a history of previous operation on a skin or eye tumour should be rejected. Bakody et al (1950) go yet further:…”

“…Ray and Foot (1940) first drew attention to the resemblance between localized " melanomas " and meningiomas, and Bakody, Hazard, and Gardner (1950) report a case where a mass, localized to L2-L4, was excised and diagnosed as a melanoma. Six years after the operation, as the patient was still well, the slide of the previous operation specimen was reviewed and the tumour was found to be a meningioma.…”