Pigmented villonodular synovitis of joints

Mankin, Henry J.; Trahan, Carol; Hornicek, Francis J.

doi:10.1002/jso.21835

Cited by 75 publications

(65 citation statements)

References 33 publications

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“…Progression of arthritis to the point of arthroplasty is an important outcome measure and represents the ultimate failure point in joint preservation. Our rate of conversion to arthroplasty (8%) is similar to the reported rates of 5% to 10% [4,11,14].…”

Section: Discussionsupporting

confidence: 88%

Does Combined Open and Arthroscopic Synovectomy for Diffuse PVNS of the Knee Improve Recurrence Rates?

Colman

Weiß

et al. 2013

Clinical Orthopaedics &Amp; Related Research

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Background Diffuse-type pigmented villonodular synovitis (PVNS) has a high local recurrence rate and as such can lead to erosive destruction of the involved joint. Multiple surgical modalities exist, but it is unknown which technique best minimizes local recurrence and surgical morbidity. Questions/purposes We compared recurrence rates, arthritis progression, and complications between arthroscopic and open modalities for diffuse PVNS of the knee.

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Section: Discussionsupporting

confidence: 88%

Does Combined Open and Arthroscopic Synovectomy for Diffuse PVNS of the Knee Improve Recurrence Rates?

Colman

Weiß

et al. 2013

Clinical Orthopaedics &Amp; Related Research

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“…PVNS is a benign proliferative growth of the synovium (1). As in our case, MRI provides specific findings of PVNS, which exhibits predominant hypointensity on all pulse sequences (2).…”

supporting

confidence: 60%

Pigmented Villonodular Synovitis of the Ankle

Lin

Cheng

et al. 2013

Intern. Med.

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A 24-year-old woman presented with painful swelling of the left ankle lasting for several months. She denied any history of prior trauma or surgery. Her level of C-reactive protein was 2.4 mg/L (normal reference <6 mg/L). Plain radiographs showed an area of soft tissue density in the anteromedial aspect of the left ankle joint. Magnetic resonance imaging (MRI) revealed a 3.4×2.3×3.7-cm soft tissue lesion in the anterior aspect of the ankle with compression and displacement of the extensor digitorum longus and the extensor hallucis longus. The lesion exhibited dark T1 and T2 signals (Pictures 1, 2), intermediate to low signals on fat-saturated proton density-weighted images and heterogeneous enhancement following gadolinium administration. Under suspicion of a diagnosis of pigmented villonodular synovitis (PVNS) of the intertarsal joint, the patient underwent extensive excision of the tumor. Pathologic examinations confirmed the diagnosis of PVNS. The histopathology (Picture 3) demonstrated a diffuse-type giant cell tumor with a nodular appearance and an infiltrative border into the adipose tissue (red

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“…This includes the entity that used to be called pigmented villonodular synovitis (PVNS). The lesion can either present as a single nodule (localised form), or as multiple nodules (diffuse form) along a synovial layer or tendon sheath [1][2][3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

“…Surgery is the mainstay of treatment, but local failure is frequent, with local relapse rates up to 50% [2,7,8]. Furthermore, repetitive surgical treatment can lead to substantial morbidity to the joints and quality of life impairment.…”

Section: Introductionmentioning

confidence: 99%

Tenosynovial giant cell tumour/pigmented villonodular synovitis: Outcome of 294 patients before the era of kinase inhibitors

Palmerini¹,

Staals²,

Maki³

et al. 2015

European Journal of Cancer

108

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Pigmented villonodular synovitis of joints

Abstract: Pigmented villonodular disease of joints is a rare entity, mostly occurring in the knee and foot. The principal treatment is surgical excision which is most often successful in these sites but leads to problems at other locations, especially the hip.

Cited by 75 publications

References 33 publications

Does Combined Open and Arthroscopic Synovectomy for Diffuse PVNS of the Knee Improve Recurrence Rates?

Does Combined Open and Arthroscopic Synovectomy for Diffuse PVNS of the Knee Improve Recurrence Rates?

Pigmented Villonodular Synovitis of the Ankle

Tenosynovial giant cell tumour/pigmented villonodular synovitis: Outcome of 294 patients before the era of kinase inhibitors

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