“…1,28,[32][33][34] Only 31 out of the 52 PVNS-TMJ cases (59%) included a possible differential diagnosis, but in 7 (13%) PVNS was included in the differential diagnosis, 24,[35][36][37][38][39][40] whereas 5 (9%) proposed the diagnosis of malignant or metastatic disease. 31,[40][41][42][43] The clinical and imaging features prompted us to propose the diagnostic hypothesis of malignant neoplasia or metastasis in the present case. Even though the TMJ region is an uncommon site for malignant neoplasias, preauricular swellings are more commonly malignant, including adenoid cystic carcinoma, mucoepidermoid carcinoma, malignant lymphoma, melanoma, squamous cell carcinoma, chondrosarcoma, synovial sarcoma, osteosarcoma, and fibrosarcoma.…”